Protein: AKTS1
Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate)

Gene: AKTS1, AKT1S1
Organism: Homo sapiens
Interactions: 35
UniProt ID: Q96B36

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006469 - negative regulation of protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1322615

RPTOR
Regulatory-associated protein of mTOR

14

1

Small-scale

0.761

High

839337

MTOR
Serine/threonine-protein kinase mTOR

10

1

Small-scale

0.760

High

730128

1433B
14-3-3 protein beta/alpha

6

6

Small-scale

0.729

High

1049648

1433F
14-3-3 protein eta

6

6

Small-scale

0.729

High

966718

1433G
14-3-3 protein gamma

5

6

High-throughput

0.718

High

728372

AKT1
RAC-alpha serine/threonine-protein kinase

4

4

Small-scale

0.686

High

691316

1433T
14-3-3 protein theta

4

6

Small-scale

0.686

High

990585

1433Z
14-3-3 protein zeta/delta

3

6

Small-scale

0.656

High

1384059

AKTS1
Proline-rich AKT1 substrate 1

2

0

Small-scale

0.592

High

279448

TULP3
Tubby-related protein 3

2

0

High-throughput

0.585

High

1150149

TCEA2
Transcription elongation factor A protein 2

1

0

High-throughput

0.518

High

480258

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

625546

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

971858

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.513

High

287721

KS6A5
Ribosomal protein S6 kinase alpha-5

1

4

High-throughput

0.508

High

1384061

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.480

High

122968

SGK1
Serine/threonine-protein kinase Sgk1

1

4

Small-scale

0.479

High

173190

XPO1
Exportin-1

1

1

High-throughput

0.479

High

941230

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.460

High

558999

LYL1
Protein lyl-1

1

0

High-throughput

0.458

High

692114

MARK3
MAP/microtubule affinity-regulating kinase 3

1

0

Small-scale

0.458

High

994329

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

Small-scale

0.458

High

1108012

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

1121296

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

1366976

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1384060

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.458

High

1384062

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

541047

PIM1
Serine/threonine-protein kinase pim-1

1

5

Small-scale

0.445

High

1103015

CENPR
Centromere protein R

1

0

High-throughput

0.438

High

347231

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.426

High

537669

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.426

High

1007753

RAE1L
mRNA export factor RAE1

1

0

High-throughput

0.426

High

1246919

RICTR
Rapamycin-insensitive companion of mTOR

1

0

Small-scale

0.426

High

1258534

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025