HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27634302
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 746
+	Hs
		996877 SSRP1_HUMAN (1-709): 0: 805: 100.00		SETD2_HUMAN (190-732): 2.07e-89: 310: 16.64
+	Hs
		1080371 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		1149777 TOX4_MOUSE (496-618): 8.38e-31: 130: 29.03		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		643350 HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		567706 UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		975232 SSRP1_HUMAN (1-709): 0: 805: 100.00		KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54
+	Sc
		810359 POB3_YEAST (4-504): 0: 541: 29.66		SET2_YEAST (470-733): 1.22e-59: 216: 25.56
+	Hs
		1300928 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		SETD2_HUMAN (190-732): 2.07e-89: 310: 16.64
+	Hs
		297441 TOX4_HUMAN (484-678): 7.24e-32: 133: 23.86		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		818361 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Hs
		818438 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		SETD2_HUMAN (190-732): 2.07e-89: 310: 16.64
+	Hs
		1300945 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27
+	Hs
		1296398 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		331701 HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03
+	Hs
		225789 SOX15_HUMAN (513-702): 2.03e-33: 130: 15.10		EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27
+	Hs
		1296420 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		225772 SOX15_HUMAN (513-702): 2.03e-33: 130: 15.10		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		818475 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27
+	Hs
		818358 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		817951 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54