HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: SPT6H (Q7KZ85)
Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)
Gene: SUPT6H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0031491 - nucleosome binding GO:0042393 - histone binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 709 Hs			1 1726
+	Hs
		449757 HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04		SPT6H_HUMAN (1-1726): 0: 1802: 100.00
+	Ce
		136654 SSP1B_CAEEL (1-695): 0: 648: 36.25		SPT6H_CAEEL (3-1538): 0: 1171: 34.73
+	Sc
		619169 POB3_YEAST (4-504): 0: 541: 29.66		SPT6_YEAST (15-1512): 0: 812: 22.21
+	Hs
		996790 SSRP1_HUMAN (1-709): 0: 805: 100.00		LEO1_HUMAN (1-345): 1.27e-13: 78.1: 13.68
+	Hs
		1234304 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		SRBD1_HUMAN (218-1212): 0: 597: 16.76
+	Hs
		818506 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		MDN1_HUMAN (6-680): 7.05e-92: 335: 12.40
+	Hs
		818296 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		LEO1_HUMAN (1-345): 1.27e-13: 78.1: 13.68
+	Hs
		817913 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		MAP1A_HUMAN (7-416): 6.64e-11: 70: 13.08