HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: H2A3 (Q7L7L0)
Histone H2A type 3 (H2A-clustered histone 25)
Gene: H2AC25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	24352239
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106, Histone_H2A_C~Rtt106
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006337 - nucleosome disassembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 130
+	Hs
		391670 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2A1B_HUMAN (1-130): 7.3e-68: 202: 99.23
+	Hs
		470362 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2A1_HUMAN (1-130): 5.87e-68: 202: 97.69
+	Hs
		996711 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2A2A_HUMAN (1-130): 4.18e-68: 202: 97.69
+	Hs
		996856 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2A1J_HUMAN (1-128): 2.34e-67: 201: 96.88
+	Hs
		996754 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2A2B_HUMAN (1-130): 1.66e-66: 199: 94.62
+	Hs
		996693 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2A2C_HUMAN (1-130): 2.58e-65: 195: 96.15
+	Hs
		996868 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2AJ_HUMAN (1-126): 3.83e-65: 195: 95.24
+	Hs
		555429 SSRP1_HUMAN (1-709): 0: 805: 100.00		H2AX_HUMAN (1-130): 5.7e-64: 192: 88.81
+	Ce
		136713 SSP1B_CAEEL (1-695): 0: 648: 36.25		Q27485_CAEEL (17-121): 3.24e-54: 167: 90.48
+	Sc
		392564 POB3_YEAST (4-504): 0: 541: 29.66		H2A2_YEAST (16-128): 1.62e-59: 181: 80.53
+	Sc
		392198 POB3_YEAST (4-504): 0: 541: 29.66		H2A1_YEAST (16-127): 4.87e-53: 164: 81.25
+	Hs
		1151386 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2A2A_HUMAN (1-130): 4.18e-68: 202: 97.69
+	Hs
		391917 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2A1B_HUMAN (1-130): 7.3e-68: 202: 99.23
+	Hs
		470568 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2A1_HUMAN (1-130): 5.87e-68: 202: 97.69
+	Hs
		1087107 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2A2C_HUMAN (1-130): 2.58e-65: 195: 96.15
+	Hs
		555655 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		H2AX_HUMAN (1-130): 5.7e-64: 192: 88.81
+	Hs
		594829 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		H2A1D_HUMAN (1-130): 6.69e-68: 202: 98.46
+	Sc
		392450 RT106_YEAST (337-544): 3.23e-31: 129: 17.37		H2A2_YEAST (16-128): 1.62e-59: 181: 80.53
+	Sc
		392264 NHP6B_YEAST (520-619): 7.39e-28: 109: 34.00		H2A2_YEAST (16-128): 1.62e-59: 181: 80.53
+	Sc
		392031 NHP6B_YEAST (520-619): 7.39e-28: 109: 34.00		H2A1_YEAST (16-127): 4.87e-53: 164: 81.25