HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: DDX42 (Q86XP3)
ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125)
Gene: DDX42

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 709 Hs			1 938
+	Hs
		996809 SSRP1_HUMAN (1-709): 0: 805: 100.00		DDX17_HUMAN (189-774): 3.85e-154: 473: 34.33
+	Hs
		571415 SSRP1_HUMAN (1-709): 0: 805: 100.00		DDX5_HUMAN (197-734): 2.1e-147: 452: 35.37
+	Hs
		297518 TOX4_HUMAN (484-678): 7.24e-32: 133: 23.86		DDX42_HUMAN (1-938): 0: 739: 100.00
+	Hs
		617326 SP100_HUMAN (486-629): 1.52e-24: 111: 28.86		DDX42_HUMAN (1-938): 0: 739: 100.00
+	Hs
		1271630 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		DDX17_HUMAN (189-774): 3.85e-154: 473: 34.33
+	Hs
		571557 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		DDX5_HUMAN (197-734): 2.1e-147: 452: 35.37
+	Hs
		818320 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		DDX17_HUMAN (189-774): 3.85e-154: 473: 34.33
+	Hs
		134175 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		DDX3X_HUMAN (123-662): 1.87e-134: 420: 29.84
+	Hs
		571352 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		DDX5_HUMAN (197-734): 2.1e-147: 452: 35.37
+	Hs
		133924 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		DDX3X_HUMAN (123-662): 1.87e-134: 420: 29.84
+	Dm
		580724 HMG2_DROME (542-706): 4.32e-17: 86: 20.71		DDX17_DROME (35-638): 1.84e-136: 427: 32.24