HitPredict

Interactor 1: F5H1N7 (F5H1N7)
Capping protein inhibiting regulator of actin dynamics
Gene: CRACD

Interactor 2: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1226 Hs			1 2647
+	Hs
		598189 CRACD_HUMAN (12-1226): 2.65e-178: 560: 98.27		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598338 MYO5C_HUMAN (108-536): 2.12e-25: 116: 15.22		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		597987 MYH11_HUMAN (1-470): 1.06e-13: 78.5: 9.28		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		148392 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598129 PLEC_HUMAN (132-702): 3.4e-11: 70.4: 9.78		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		148205 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		FLNB_HUMAN (28-2647): 0: 2710: 69.63
+	Hs
		148807 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		FLNC_HUMAN (32-2647): 0: 1432: 35.96
+	Hs
		963324 DCTN1_HUMAN (76-532): 5.26e-38: 157: 20.25		SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62
+	Hs
		963431 MYO5C_HUMAN (108-536): 2.12e-25: 116: 15.22		SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62
+	Hs
		963335 ITSN1_HUMAN (110-452): 5.95e-15: 82.7: 15.73		SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62
+	Hs
		211671 MYO5C_HUMAN (108-536): 2.12e-25: 116: 15.22		ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01
+	Hs
		148690 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62
+	Hs
		148330 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		SPTB1_HUMAN (2-460): 2.89e-117: 419: 23.57
+	Hs
		148463 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62
+	Hs
		148339 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53
+	Hs
		148722 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		ACTN3_HUMAN (30-460): 2.85e-118: 401: 25.28
+	Hs
		148171 CTRO_HUMAN (312-773): 2.22e-11: 70.8: 12.08		ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01
+	Dm
		90591 MYSN_DROME (15-751): 1.36e-21: 104: 11.22		E1JGS7_DROME (500-1263): 5.3e-88: 323: 23.04
+	Hs
		957543 KIF7_HUMAN (150-742): 9.52e-29: 127: 14.38		PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81
+	Dm
		1303393 MYSN_DROME (15-751): 1.36e-21: 104: 11.22		FLNA_DROME (2539-2646): 9.6e-12: 73.5: 28.57