Interactor 1: RBL2 (Q08999)
Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)
Gene: RBL2

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 15077161
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0005654 - nucleoplasm
GO:0006325 - chromatin organization
GO:1990841 - promoter-specific chromatin binding
GO:2000134 - negative regulation of G1/S transition of mitotic cell cycle
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1139
Hs

1 746
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024