HitPredict

Interactor 1: MZT1 (Q08AG7)
Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1)
Gene: MZT1

Interactor 2: GCP3 (Q96CW5)
Gamma-tubulin complex component 3 (GCP-3) (hGCP3) (Gamma-ring complex protein 104 kDa) (h104p) (hGrip104) (Spindle pole body protein Spc98 homolog) (hSpc98)
Gene: TUBGCP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	26496610, 28514442, 33961781, 23443559, 20360068
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000930 - gamma-tubulin complex GO:0005813 - centrosome GO:0005819 - spindle GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 82 Hs			1 907
+	At
		1322824 MZT1B_ARATH (20-71): 8.36e-20: 76.7: 48.08		GACP3_ARATH (1-892): 0: 706: 30.45
+	At
		1321296 MZT1A_ARATH (20-71): 5.94e-17: 69.4: 46.15		GACP3_ARATH (1-892): 0: 706: 30.45
+	Hs
		997304 MZT1_HUMAN (17-82): 7.89e-25: 89.8: 100.00		GCP2_HUMAN (38-895): 0: 582: 22.21
+	Sp
		474424 MZT1_SCHPO (20-72): 3.3e-18: 72.5: 47.17		ALP6_SCHPO (225-900): 9.74e-156: 480: 31.06
+	Hs
		997312 MZT1_HUMAN (17-82): 7.89e-25: 89.8: 100.00		GCP4_HUMAN (250-888): 4.32e-149: 457: 16.83
+	At
		1340728 MZT1B_ARATH (20-71): 8.36e-20: 76.7: 48.08		GACP4_ARATH (278-888): 1.08e-121: 388: 16.49
+	Hs
		997305 MZT1_HUMAN (17-82): 7.89e-25: 89.8: 100.00		Q9BVR6_HUMAN (382-659): 2.99e-68: 232: 17.06
+	Hs
		70861 MZT1_HUMAN (17-82): 7.89e-25: 89.8: 100.00		B2RWN4_HUMAN (245-560): 6.96e-59: 222: 17.77
+	Hs
		997301 MZT1_HUMAN (17-82): 7.89e-25: 89.8: 100.00		GCP6_HUMAN (245-560): 7.43e-59: 222: 17.77
+	Hs
		997302 MZT1_HUMAN (17-82): 7.89e-25: 89.8: 100.00		GCP5_HUMAN (205-577): 2.92e-11: 69.5: 14.29