Interactor 1: VAC14 (Q08AM6)
Protein VAC14 homolog (Tax1-binding protein 2)
Gene: VAC14

Interactor 2: FYV1 (Q9Y2I7)
1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1)
Gene: PIKFYVE

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.725

The method score is based on:

Property Details
Experiments 25416956, 28514442, 29892012, 33961781, 19037259
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0005829 - cytosol
GO:0006661 - phosphatidylinositol biosynthetic process
GO:0010008 - endosome membrane
GO:0031901 - early endosome membrane
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 782
Hs

1 2098
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024