HitPredict

Interactor 1: DMWD (Q09019)
Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9)
Gene: DMWD

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25011449
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 674 Hs			1 768
+	Hs
		929445 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042101 POC1B_HUMAN (313-621): 8.19e-42: 160: 13.33		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		197016 PRP4_HUMAN (62-311): 1.14e-28: 122: 14.40		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041647 TAF5_HUMAN (69-312): 5.57e-22: 103: 13.93		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		903207 WDR5_HUMAN (402-646): 6.73e-18: 87.6: 7.97		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		792982 LIS1_HUMAN (61-356): 1.01e-54: 194: 12.09		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		929446 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043114 POC1B_HUMAN (313-621): 8.19e-42: 160: 13.33		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043469 POC1B_HUMAN (313-621): 8.19e-42: 160: 13.33		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		245601 TBL1X_HUMAN (321-629): 1.44e-32: 134: 13.07		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043562 TBL1R_HUMAN (321-629): 1.93e-32: 133: 12.84		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043085 WDR5B_HUMAN (360-666): 3.59e-27: 114: 12.46		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043499 FBXW7_HUMAN (75-349): 3.2e-27: 119: 7.77		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043441 WDR5B_HUMAN (360-666): 3.59e-27: 114: 12.46		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		929443 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		929444 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Mm
		1257398 FBXW7_MOUSE (75-349): 1.62e-27: 120: 7.77		CUL1_MOUSE (17-768): 0: 709: 30.53
+	Hs
		1041133 FBXW7_HUMAN (75-349): 3.2e-27: 119: 7.77		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		903206 WDR5_HUMAN (402-646): 6.73e-18: 87.6: 7.97		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Sc
		743044 GBLP_YEAST (246-527): 9.07e-48: 172: 18.71		CDC53_YEAST (30-768): 0: 573: 22.08