HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: ARI5B (Q14865)
AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (MRF1-like protein) (Modulator recognition factor 2) (MRF-2)
Gene: ARID5B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 1188
+	Hs
		997944 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		KDM5B_HUMAN (243-535): 7.32e-62: 234: 17.82
+	Hs
		1083421 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		KDM5B_HUMAN (243-535): 7.32e-62: 234: 17.82
+	Hs
		666528 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		KDM5A_HUMAN (240-509): 9.16e-51: 199: 18.15
+	Hs
		666534 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		KDM5A_HUMAN (240-509): 9.16e-51: 199: 18.15
+	Mm
		1141932 RBBP4_MOUSE (1-425): 4.3e-124: 367: 100.00		JARD2_MOUSE (257-462): 1.57e-37: 155: 13.24
+	Hs
		997748 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		ARI4B_HUMAN (323-536): 9.31e-37: 153: 24.89
+	Hs
		997840 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		JARD2_HUMAN (257-462): 9.34e-37: 153: 14.16
+	Hs
		666481 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		ARI4A_HUMAN (321-537): 2.26e-32: 139: 19.82
+	Hs
		1083269 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		ARI4B_HUMAN (323-536): 9.31e-37: 153: 24.89
+	Hs
		1083338 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		JARD2_HUMAN (257-462): 9.34e-37: 153: 14.16
+	Hs
		666486 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		ARI4A_HUMAN (321-537): 2.26e-32: 139: 19.82
+	Dm
		1213324 EBI_DROME (2-259): 3.6e-48: 176: 14.02		OSA_DROME (232-530): 2.49e-43: 175: 17.46
+	Dm
		1099176 CAF1_DROME (226-419): 3.68e-29: 119: 18.36		Q9VT00_DROME (247-406): 1.01e-32: 140: 16.57
+	Hs
		1147485 NLE1_HUMAN (8-106): 1.77e-21: 98.3: 10.58		ARID2_HUMAN (312-425): 1.91e-29: 129: 27.12