HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: ZN827 (Q17R98)
Zinc finger protein 827
Gene: ZNF827

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.681

Property	Details
Experiments	25150861, 30045876, 37689310
Identification Methods	affinity chromatography technology, pull down, x-ray crystallography, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0000785 - chromatin GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 1081
+	Hs
		1083264 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		ZN827_HUMAN (1011-1069): 7.37e-10: 65.6: 33.90
+	Hs
		312070 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		ZBT7A_HUMAN (362-455): 1.1e-09: 64.3: 36.84
+	Hs
		245549 TBL1X_HUMAN (207-424): 3.72e-35: 138: 17.63		PRDM1_HUMAN (372-455): 1.8e-09: 63.9: 33.33
+	Dm
		1099175 CAF1_DROME (226-419): 3.68e-29: 119: 18.36		Q9VS55_DROME (372-457): 9.3e-11: 68.2: 40.70