HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: CR3L3 (Q68CJ9)
Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3) (Transcription factor CREB-H) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 3]
Gene: CREB3L3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	26108621
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 461
+	Hs
		891617 GSK3B_HUMAN (39-389): 1.85e-112: 336: 29.12		CR3L3_HUMAN (1-461): 2.3e-133: 394: 100.00
+	Hs
		429706 CSK21_HUMAN (1-391): 2e-136: 396: 100.00		JUN_HUMAN (10-312): 2.99e-34: 132: 16.72
+	Hs
		593079 CSK21_HUMAN (1-391): 2e-136: 396: 100.00		CREB1_HUMAN (89-314): 6.77e-29: 117: 18.46
+	Hs
		583528 CSK21_HUMAN (1-391): 2e-136: 396: 100.00		ATF2_HUMAN (38-319): 2.29e-26: 113: 14.53
+	Hs
		617093 CSK21_HUMAN (1-391): 2e-136: 396: 100.00		ATF1_HUMAN (71-294): 2.39e-26: 109: 18.30
+	Hs
		429285 CSK22_HUMAN (1-334): 1.12e-119: 352: 85.08		JUN_HUMAN (10-312): 2.99e-34: 132: 16.72
+	At
		1183881 MPK5_ARATH (22-364): 3.08e-118: 349: 25.92		Q9SL54_ARATH (93-307): 3.04e-31: 122: 19.82
+	At
		1045013 MPK6_ARATH (2-364): 2.05e-118: 351: 23.94		POF21_ARATH (53-357): 4.12e-28: 117: 12.34
+	Hs
		429530 GSK3B_HUMAN (39-389): 1.85e-112: 336: 29.12		JUN_HUMAN (10-312): 2.99e-34: 132: 16.72
+	Hs
		593057 GSK3B_HUMAN (39-389): 1.85e-112: 336: 29.12		CREB1_HUMAN (89-314): 6.77e-29: 117: 18.46