HitPredict

Interactor 1: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0000380 - alternative mRNA splicing, via spliceosome GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 790 Hs			1 344
+	Hs
		992738 NCBP1_HUMAN (1-790): 0: 1180: 100.00		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		998172 NCBP1_HUMAN (1-790): 0: 1180: 100.00		RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05
+	Hs
		998032 NCBP1_HUMAN (1-790): 0: 1180: 100.00		SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22
+	Hs
		998033 NCBP1_HUMAN (1-790): 0: 1180: 100.00		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		998037 NCBP1_HUMAN (1-790): 0: 1180: 100.00		PABP4_HUMAN (101-191): 1.26e-12: 70.7: 21.88
+	Hs
		516479 NCBP1_HUMAN (1-790): 0: 1180: 100.00		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Sc
		633935 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		GBP2_YEAST (4-203): 4.8e-23: 100: 19.05
+	Sc
		710199 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94
+	Sc
		376713 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		PABP_YEAST (99-194): 1.33e-11: 67.6: 19.80