HitPredict

Interactor 1: SF3B4 (Q09442)
Splicing factor 3B subunit 4 (Spliceosome-associated protein 49)
Gene: sap-49

Interactor 2: Q9U2T9 (Q9U2T9)
Intersectin-1
Gene: itsn-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.50	0.543

Property	Details
Experiments	18298590, 23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 388 Ce			1 1085
+	Hs
		557702 SF3B4_HUMAN (1-383): 2.89e-56: 191: 57.18		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Hs
		209057 SF3B4_HUMAN (1-383): 2.89e-56: 191: 57.18		NCK2_HUMAN (660-960): 3.34e-25: 110: 18.69
+	Hs
		1073578 SF3B4_HUMAN (1-383): 2.89e-56: 191: 57.18		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Ce
		998580 SF3B4_CAEEL (1-383): 1.02e-60: 202: 100.00		Q95PW9_CAEEL (670-843): 3.79e-09: 62: 26.55
+	Hs
		924591 SF3B4_HUMAN (1-383): 2.89e-56: 191: 57.18		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		516450 PABP1_HUMAN (5-206): 2.21e-38: 147: 32.02		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Sc
		376714 PABP_YEAST (90-189): 8.92e-17: 84: 31.00		EDE1_YEAST (171-297): 9.84e-10: 65: 22.05
+	Dm
		53017 Q9W424_DROME (89-323): 3.38e-10: 62.9: 17.45		A1Z866_DROME (514-837): 1.83e-15: 83.3: 15.59
+	Dm
		1197449 Q9W424_DROME (89-323): 3.38e-10: 62.9: 17.45		Q86P80_DROME (514-837): 2.58e-15: 82.5: 15.59