HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23870121, 33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0043627 - response to estrogen GO:0045815 - transcription initiation-coupled chromatin remodeling
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 538
+	Hs
		998802 EP300_HUMAN (1-2414): 0: 1113: 100.00		WDR44_HUMAN (53-281): 4.14e-54: 198: 24.46
+	Hs
		998787 EP300_HUMAN (1-2414): 0: 1113: 100.00		SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79
+	Hs
		903172 EP300_HUMAN (1-2414): 0: 1113: 100.00		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		1070796 CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02		RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00
+	Hs
		1070746 KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13		RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00
+	Hs
		1070752 CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25		RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00
+	Hs
		1281528 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		1164185 BRWD1_HUMAN (1007-1168): 2.52e-44: 180: 32.93		BRWD3_HUMAN (228-450): 4.8e-15: 80.8: 12.86
+	Hs
		164439 TRI66_HUMAN (268-1197): 1.08e-40: 168: 12.26		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		631541 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		631525 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		1067068 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		1056932 MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82		SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59
+	Hs
		1056974 MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82		WDR33_HUMAN (198-342): 2.09e-17: 88.1: 10.67
+	Hs
		297832 K0754_HUMAN (66-444): 1.97e-12: 75.5: 10.28		BRWD3_HUMAN (228-450): 4.8e-15: 80.8: 12.86
+	Hs
		1164179 PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86		BRWD3_HUMAN (228-450): 4.8e-15: 80.8: 12.86
+	Hs
		1199169 PB1_HUMAN (1081-1145): 9.68e-11: 69.8: 36.92		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		903374 KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		903405 CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41