HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 582
+	Hs
		403203 EP300_HUMAN (1-2414): 0: 1113: 100.00		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		998651 EP300_HUMAN (1-2414): 0: 1113: 100.00		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516480 EP300_HUMAN (1-2414): 0: 1113: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		998832 EP300_HUMAN (1-2414): 0: 1113: 100.00		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		999142 EP300_HUMAN (1-2414): 0: 1113: 100.00		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		998821 EP300_HUMAN (1-2414): 0: 1113: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		998750 EP300_HUMAN (1-2414): 0: 1113: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		631451 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1066985 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116598 CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		403371 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		1174875 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		516745 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		631575 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		1067122 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		516595 KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		1262793 PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02