HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: CPSF7 (Q8N684)
Cleavage and polyadenylation specificity factor subunit 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Cleavage factor Im complex 59 kDa subunit) (CFIm59) (Pre-mRNA cleavage factor Im 59 kDa subunit)
Gene: CPSF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 471
+	Hs
		998775 EP300_HUMAN (1-2414): 0: 1113: 100.00		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		998651 EP300_HUMAN (1-2414): 0: 1113: 100.00		PABP4_HUMAN (73-165): 2.96e-11: 67.6: 18.28
+	Hs
		516480 EP300_HUMAN (1-2414): 0: 1113: 100.00		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36
+	Hs
		1084666 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		1056844 MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		1084554 CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25		CPSF6_HUMAN (1-451): 1.98e-76: 250: 39.51
+	Hs
		516745 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36
+	Hs
		516595 KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13		PABP1_HUMAN (73-165): 7.95e-10: 63: 19.36