Interactor 1: TSC1 (Q09778)
Tuberous sclerosis 1 protein homolog
Gene: TSC1

Interactor 2: TSC2 (Q9UUG9)
Tuberous sclerosis 2 protein homolog
Gene: TSC2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 12136010
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0032007 - negative regulation of TOR signaling
GO:0033596 - TSC1-TSC2 complex
GO:1904262 - negative regulation of TORC1 signaling
and 3 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 899
Sp

1 1339
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024