Protein: ARPC2
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)

Gene: ARPC2
Organism: Homo sapiens
Interactions: 153
UniProt ID: O15144

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005768 - endosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

168910

ARP2
Actin-related protein 2

8

6

High-throughput

0.966

High

168909

ARP3
Actin-related protein 3

7

6

Small-scale

0.962

High

168982

ARP3B
Actin-related protein 3B

6

6

High-throughput

0.950

High

168906

ARPC4
Actin-related protein 2/3 complex subunit 4

5

3

Small-scale

0.928

High

168914

ACTG
Actin, cytoplasmic 2

2

2

High-throughput

0.789

High

168681

ARC1B
Actin-related protein 2/3 complex subunit 1B

10

4

Small-scale

0.758

High

168961

ARC1A
Actin-related protein 2/3 complex subunit 1A

8

4

Small-scale

0.753

High

168851

ARPC3
Actin-related protein 2/3 complex subunit 3

8

2

Small-scale

0.749

High

168852

ARPC5
Actin-related protein 2/3 complex subunit 5

4

3

Small-scale

0.696

High

168907

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.691

High

168965

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

3

3

Small-scale

0.660

High

168977

ANLN
Anillin

3

1

High-throughput

0.656

High

168880

CFTR
Cystic fibrosis transmembrane conductance regulator

3

0

High-throughput

0.622

High

168924

SRC8
Src substrate cortactin

2

2

Small-scale

0.611

High

168931

NF2L2
Nuclear factor erythroid 2-related factor 2

1

0

Small-scale

0.577

High

168878

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.576

High

168935

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

1

Small-scale

0.571

High

168857

DOK2
Docking protein 2

2

0

High-throughput

0.547

High

168860

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.547

High

168960

ESR2
Estrogen receptor beta

2

0

High-throughput

0.547

High

168969

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

1

High-throughput

0.541

High

168899

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

168900

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.536

High

168917

CALD1
Caldesmon

1

2

High-throughput

0.536

High

168932

DREB
Drebrin

1

1

High-throughput

0.536

High

168937

CYTSA
Cytospin-A

1

2

High-throughput

0.536

High

168963

MYO19
Unconventional myosin-XIX

1

2

High-throughput

0.536

High

168966

COR1B
Coronin-1B

1

1

Small-scale

0.536

High

168978

MYO5C
Unconventional myosin-Vc

1

1

High-throughput

0.536

High

168986

DBNL
Drebrin-like protein

1

3

High-throughput

0.536

High

168854

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.513

High

168888

1433B
14-3-3 protein beta/alpha

1

0

High-throughput

0.513

High

168892

MYH9
Myosin-9

1

0

High-throughput

0.513

High

168893

ARL3
ADP-ribosylation factor-like protein 3

1

0

High-throughput

0.513

High

168898

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.513

High

168902

DAPK1
Death-associated protein kinase 1

1

0

High-throughput

0.513

High

168911

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

0

High-throughput

0.513

High

168922

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

168923

BOP1
Ribosome biogenesis protein BOP1

1

0

High-throughput

0.513

High

168925

FA50A
Protein FAM50A

1

0

High-throughput

0.513

High

168929

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

168933

CL16A
Protein CLEC16A

1

0

High-throughput

0.513

High

168948

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

168950

AL14E
ARL14 effector protein

1

0

High-throughput

0.513

High

168964

ZN830
Zinc finger protein 830

1

0

High-throughput

0.513

High

168967

KIFC1
Kinesin-like protein KIFC1

1

0

High-throughput

0.513

High

168979

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.513

High

168980

ARL8B
ADP-ribosylation factor-like protein 8B

1

0

High-throughput

0.513

High

168983

STK26
Serine/threonine-protein kinase 26

1

0

High-throughput

0.513

High

168987

DP13A
DCC-interacting protein 13-alpha

1

0

High-throughput

0.513

High

168989

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

High-throughput

0.513

High

168995

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.513

High

160256

AURKA
Aurora kinase A

1

1

Small-scale

0.501

High

168896

WASP
Actin nucleation-promoting factor WAS

1

6

Small-scale

0.501

High

168944

ARPIN
Arpin

1

0

Small-scale

0.493

High

168991

SIK3
Serine/threonine-protein kinase SIK3

1

1

High-throughput

0.489

High

120210

RHOD
Rho-related GTP-binding protein RhoD

1

2

High-throughput

0.479

High

126881

WASL
Actin nucleation-promoting factor WASL

1

5

Small-scale

0.479

High

128943

PLK4
Serine/threonine-protein kinase PLK4

1

1

Small-scale

0.479

High

168863

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.479

High

168864

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.479

High

168876

TPC2B
Trafficking protein particle complex subunit 2B

1

1

High-throughput

0.479

High

168889

RYK
Tyrosine-protein kinase RYK

1

1

High-throughput

0.479

High

168894

PPARG
Peroxisome proliferator-activated receptor gamma

1

1

Small-scale

0.479

High

168903

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

168908

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.479

High

168927

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

168941

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

1

High-throughput

0.479

High

168943

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.479

High

168947

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.479

High

168952

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

168956

RN138
E3 ubiquitin-protein ligase RNF138

1

1

High-throughput

0.479

High

168974

SIK2
Serine/threonine-protein kinase SIK2

1

1

Small-scale

0.479

High

168976

MYO10
Unconventional myosin-X

1

1

Small-scale

0.479

High

168993

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

162201

XPO1
Exportin-1

1

0

High-throughput

0.458

High

167765

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

168853

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

Small-scale

0.458

High

168855

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

168856

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

168859

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

168862

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

168865

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

168866

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

168867

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

168870

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

168871

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

168873

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

168874

GLI1
Zinc finger protein GLI1

1

0

Small-scale

0.458

High

168879

CADH1
Cadherin-1

1

0

Small-scale

0.458

High

168881

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

168882

VINC
Vinculin

1

0

Small-scale

0.458

High

168883

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

168884

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

168886

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

0

High-throughput

0.458

High

168887

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

168891

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

168895

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

168897

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

168901

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

168904

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

168905

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

168912

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

168918

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

168920

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

168926

CUL7
Cullin-7

1

0

High-throughput

0.458

High

168928

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

168930

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

168939

ANO7
Anoctamin-7

1

0

Small-scale

0.458

High

168940

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

0

High-throughput

0.458

High

168946

CEP97
Centrosomal protein of 97 kDa

1

0

Small-scale

0.458

High

168951

DTX3
Probable E3 ubiquitin-protein ligase DTX3

1

0

Small-scale

0.458

High

168953

PARD3
Partitioning defective 3 homolog

1

0

Small-scale

0.458

High

168957

UB2Q2
Ubiquitin-conjugating enzyme E2 Q2

1

0

Small-scale

0.458

High

168968

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

168970

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

168972

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

Small-scale

0.458

High

168973

SHRPN
Sharpin

1

0

Small-scale

0.458

High

168975

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

168984

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.458

High

168985

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

168990

RNF6
E3 ubiquitin-protein ligase RNF6

1

0

High-throughput

0.458

High

168992

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

46278

A0A1W2PNV4
Actin-related protein 2/3 complex subunit 1A

1

4

High-throughput

0.445

High

168869

PAK4
Serine/threonine-protein kinase PAK 4

1

1

High-throughput

0.445

High

168875

TPC2A
Trafficking protein particle complex subunit 2

1

1

High-throughput

0.445

High

168877

CALM3
Calmodulin-3

1

1

High-throughput

0.445

High

168890

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

168916

RHOG
Rho-related GTP-binding protein RhoG

1

1

Small-scale

0.445

High

168921

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.445

High

168958

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

168971

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.437

High

168988

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.437

High

168858

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

168885

CXCR2
C-X-C chemokine receptor type 2

1

0

Small-scale

0.426

High

168913

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.426

High

168919

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

168938

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

168959

SSH1
Protein phosphatase Slingshot homolog 1

1

0

Small-scale

0.426

High

168861

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.279

Low

168915

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

168949

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.279

Low

168955

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

0

High-throughput

0.279

Low

168962

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.279

Low

168994

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.279

Low

168868

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.269

Low

168872

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

168934

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

168942

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

168945

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low

168954

CHUR
Protein Churchill

1

0

High-throughput

0.249

Low

168981

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

168936

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024