Protein: BRK1
Protein BRICK1 (BRK1)

Gene: BRK1
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q8WUW1

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0007015 - actin filament organization
GO:0008064 - regulation of actin polymerization or depolymerization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1260596

NDEL1
Nuclear distribution protein nudE-like 1

5

1

High-throughput

0.715

High

1260577

WASF1
Actin-binding protein WASF1

4

11

Small-scale

0.694

High

1260581

DTBP1
Dysbindin

4

0

High-throughput

0.675

High

209128

NCK2
Cytoplasmic protein NCK2

3

1

High-throughput

0.667

High

267303

HSBP1
Heat shock factor-binding protein 1

3

1

High-throughput

0.665

High

1260607

ABI2
Abl interactor 2

3

3

Small-scale

0.662

High

1260620

NCKP1
Nck-associated protein 1

3

2

Small-scale

0.662

High

1224621

ABI1
Abl interactor 1

2

3

High-throughput

0.628

High

1260618

WASF3
Actin-binding protein WASF3

2

11

High-throughput

0.628

High

1260628

WASF2
Actin-binding protein WASF2

2

11

High-throughput

0.628

High

1260589

AKAP9
A-kinase anchor protein 9

2

2

High-throughput

0.621

High

1255627

RBCC1
RB1-inducible coiled-coil protein 1

2

2

High-throughput

0.611

High

1260619

BAIP2
BAR/IMD domain-containing adapter protein 2

2

0

High-throughput

0.602

High

1184636

CYFP1
Cytoplasmic FMR1-interacting protein 1

2

3

Small-scale

0.601

High

925471

RAC1
Ras-related C3 botulinum toxin substrate 1

2

5

Small-scale

0.594

High

1138201

BRE1A
E3 ubiquitin-protein ligase BRE1A

2

2

High-throughput

0.567

High

1260578

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

0

High-throughput

0.551

High

1260585

SCLT1
Sodium channel and clathrin linker 1

2

0

High-throughput

0.547

High

255253

LIPA3
Liprin-alpha-3

1

2

High-throughput

0.536

High

259653

LIPA2
Liprin-alpha-2

1

2

High-throughput

0.536

High

317311

PCNT
Pericentrin

1

2

High-throughput

0.536

High

475117

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

1

High-throughput

0.536

High

557749

NCK1
SH2/SH3 adapter protein NCK1

1

1

High-throughput

0.536

High

702950

KINH
Kinesin-1 heavy chain

1

3

High-throughput

0.536

High

828605

CENPF
Centromere protein F

1

2

High-throughput

0.536

High

876302

NCKPL
Nck-associated protein 1-like

1

2

High-throughput

0.536

High

1017544

KIF5A
Kinesin heavy chain isoform 5A

1

3

High-throughput

0.536

High

1025324

LIPA1
Liprin-alpha-1

1

2

High-throughput

0.536

High

1063983

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.536

High

1164570

NHS
Actin remodeling regulator NHS

1

1

High-throughput

0.536

High

1218748

GCC2
GRIP and coiled-coil domain-containing protein 2

1

1

High-throughput

0.536

High

1255823

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

1

2

High-throughput

0.536

High

1260582

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

3

High-throughput

0.536

High

1260593

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

1

High-throughput

0.536

High

1260597

KLC2
Kinesin light chain 2

1

1

High-throughput

0.536

High

1260605

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit 4

1

1

High-throughput

0.536

High

1260606

NDE1
Nuclear distribution protein nudE homolog 1

1

1

High-throughput

0.536

High

228175

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.515

High

535493

GFAP
Glial fibrillary acidic protein

1

1

High-throughput

0.515

High

781947

PERI
Peripherin

1

1

High-throughput

0.515

High

1191489

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

255178

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

262294

ULK1
Serine/threonine-protein kinase ULK1

1

0

High-throughput

0.513

High

310985

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.513

High

430280

PROF1
Profilin-1

1

0

High-throughput

0.513

High

872917

ARSF
Arylsulfatase F

1

0

High-throughput

0.513

High

929943

ACTG
Actin, cytoplasmic 2

1

0

High-throughput

0.513

High

944553

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

0

High-throughput

0.513

High

1067449

EEA1
Early endosome antigen 1

1

0

High-throughput

0.513

High

1075492

DIXC1
Dixin

1

0

High-throughput

0.513

High

1075856

TRIPB
Thyroid receptor-interacting protein 11

1

0

High-throughput

0.513

High

1118327

GRAP1
GRIP1-associated protein 1

1

0

High-throughput

0.513

High

1163360

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

1

0

High-throughput

0.513

High

1205712

HOME1
Homer protein homolog 1

1

0

High-throughput

0.513

High

1217369

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.513

High

1219666

RHG12
Rho GTPase-activating protein 12

1

0

High-throughput

0.513

High

1237857

AL14E
ARL14 effector protein

1

0

High-throughput

0.513

High

1260584

SPTCS
Spatacsin

1

0

High-throughput

0.513

High

1260587

CEP89
Centrosomal protein of 89 kDa

1

0

High-throughput

0.513

High

1260591

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.513

High

1260601

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.513

High

1260602

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.513

High

1260603

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.513

High

1260612

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

1

0

High-throughput

0.513

High

1260614

PKHH1
Pleckstrin homology domain-containing family H member 1

1

0

High-throughput

0.513

High

1260617

TBD2B
TBC1 domain family member 2B

1

0

High-throughput

0.513

High

1260626

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

1

0

High-throughput

0.513

High

153739

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.493

High

157975

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

182366

PER1
Period circadian protein homolog 1

1

0

High-throughput

0.493

High

344531

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.493

High

456614

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

High-throughput

0.493

High

644104

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.493

High

660641

GRN
Progranulin

1

0

High-throughput

0.493

High

742426

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

770956

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.493

High

791800

HD
Huntingtin

1

0

High-throughput

0.493

High

803667

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.493

High

840771

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

848091

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.493

High

896342

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

0

High-throughput

0.493

High

1051381

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.493

High

1184509

CD37L
Hsp90 co-chaperone Cdc37-like 1

1

0

High-throughput

0.493

High

1198526

DPP9
Dipeptidyl peptidase 9

1

0

High-throughput

0.493

High

1260583

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.493

High

1260588

ATX2
Ataxin-2

1

0

High-throughput

0.493

High

1260592

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.493

High

1260623

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

229879

KIF5C
Kinesin heavy chain isoform 5C

1

3

High-throughput

0.489

High

256313

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

2

High-throughput

0.489

High

1121534

EIPR1
EARP and GARP complex-interacting protein 1

1

1

High-throughput

0.489

High

1132217

NHSL1
NHS-like protein 1

1

1

High-throughput

0.489

High

1260604

KLC4
Kinesin light chain 4

1

1

High-throughput

0.489

High

1190814

BRAP
BRCA1-associated protein

1

0

Small-scale

0.486

High

338750

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

348824

RASN
GTPase NRas

1

2

High-throughput

0.479

High

349523

RASH
GTPase HRas

1

2

High-throughput

0.479

High

350393

RASK
GTPase KRas

1

2

High-throughput

0.479

High

436430

RHOC
Rho-related GTP-binding protein RhoC

1

5

High-throughput

0.479

High

545524

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

665634

EPHB2
Ephrin type-B receptor 2

1

3

High-throughput

0.479

High

892508

RAC3
Ras-related C3 botulinum toxin substrate 3

1

5

High-throughput

0.479

High

894253

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

900735

RHOA
Transforming protein RhoA

1

5

High-throughput

0.479

High

103808

G5E9A7
DM1 locus, WD repeat containing

1

1

High-throughput

0.470

High

231650

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

155413

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

882459

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

1260611

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1260609

PCD10
Protocadherin-10

1

4

Small-scale

0.457

High

872466

EPHA5
Ephrin type-A receptor 5

1

3

High-throughput

0.437

High

872682

EPHA4
Ephrin type-A receptor 4

1

3

High-throughput

0.437

High

1072562

EPHA7
Ephrin type-A receptor 7

1

3

High-throughput

0.437

High

497344

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1260586

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.426

High

158334

PCD17
Protocadherin-17

1

5

Small-scale

0.407

High

307485

PCDH8
Protocadherin-8

1

6

Small-scale

0.407

High

1166658

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

1

Small-scale

0.407

High

1192314

Q7Z738
PCDH12 protein

1

6

Small-scale

0.407

High

1229693

NLGNX
Neuroligin-4, X-linked

1

1

Small-scale

0.407

High

1231764

NLGN1
Neuroligin-1

1

1

Small-scale

0.407

High

1250852

PCD19
Protocadherin-19

1

6

Small-scale

0.407

High

1260600

PCD18
Protocadherin-18

1

6

Small-scale

0.407

High

1260616

PCDA6
Protocadherin alpha-6

1

1

Small-scale

0.407

High

1260627

ROBO1
Roundabout homolog 1

1

1

Small-scale

0.407

High

1260625

MOFA1
MORF4 family-associated protein 1

3

0

High-throughput

0.344

High

269455

STX11
Syntaxin-11

2

0

High-throughput

0.328

High

1114445

AMZ1
Archaemetzincin-1

2

0

High-throughput

0.328

High

1260615

CBLC
E3 ubiquitin-protein ligase CBL-C

2

0

High-throughput

0.328

High

1260622

WASC3
WASH complex subunit 3

2

0

High-throughput

0.328

High

57892

CCD78
Coiled-coil domain-containing protein 78

1

0

High-throughput

0.279

Low

473146

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

740221

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.279

Low

1065665

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.279

Low

1114320

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.279

Low

1116810

CCD40
Coiled-coil domain-containing protein 40

1

0

High-throughput

0.279

Low

1120270

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.279

Low

1123257

SDK2
Protein sidekick-2

1

0

High-throughput

0.279

Low

1127278

TGO1
Transport and Golgi organization protein 1 homolog

1

0

High-throughput

0.279

Low

1130989

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.279

Low

1219795

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

0

High-throughput

0.279

Low

1238470

BANP
Protein BANP

1

0

High-throughput

0.279

Low

1240444

POC1A
POC1 centriolar protein homolog A

1

0

High-throughput

0.279

Low

1243664

NAV1
Neuron navigator 1

1

0

High-throughput

0.279

Low

1255019

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

1

0

High-throughput

0.279

Low

1260576

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1260579

BORC5
BLOC-1-related complex subunit 5

1

0

High-throughput

0.279

Low

1260580

BORC7
BLOC-1-related complex subunit 7

1

0

High-throughput

0.279

Low

1260594

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.279

Low

1260595

SRCN1
SRC kinase signaling inhibitor 1

1

0

High-throughput

0.279

Low

1260599

CCSE2
Serine-rich coiled-coil domain-containing protein 2

1

0

High-throughput

0.279

Low

1260608

NHSL3
NHS-like protein 3

1

0

High-throughput

0.279

Low

1260610

GHRL
Appetite-regulating hormone

1

0

High-throughput

0.279

Low

1260613

ODF2L
Protein BCAP

1

0

High-throughput

0.279

Low

1260621

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.279

Low

1260624

DTNA
Dystrobrevin alpha

1

0

High-throughput

0.279

Low

47274

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

135655

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.268

Low

157358

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.268

Low

199203

ZNHI1
Zinc finger HIT domain-containing protein 1

1

0

High-throughput

0.268

Low

224633

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

0

High-throughput

0.268

Low

309255

SPDEF
SAM pointed domain-containing Ets transcription factor

1

0

High-throughput

0.268

Low

316441

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.268

Low

448133

DOPO
Dopamine beta-hydroxylase

1

0

High-throughput

0.268

Low

584028

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

782446

P2RY2
P2Y purinoceptor 2

1

0

High-throughput

0.268

Low

800042

VDAC2
Voltage-dependent anion-selective channel protein 2

1

0

High-throughput

0.268

Low

933291

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.268

Low

1012460

BRME1
Break repair meiotic recombinase recruitment factor 1

1

0

High-throughput

0.268

Low

1062943

LAP4A
Lysosomal-associated transmembrane protein 4A

1

0

High-throughput

0.268

Low

1108496

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.268

Low

1134175

PHF19
PHD finger protein 19

1

0

High-throughput

0.268

Low

1200879

Q86V28
AP-1 complex subunit gamma

1

0

High-throughput

0.268

Low

1221965

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.268

Low

1229621

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

0

High-throughput

0.268

Low

1233124

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.268

Low

1237294

MAGB6
Melanoma-associated antigen B6

1

0

High-throughput

0.268

Low

1251679

Q8TAS3
PRRG2 protein

1

0

High-throughput

0.268

Low

1253845

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.268

Low

1254039

WFDC5
WAP four-disulfide core domain protein 5

1

0

High-throughput

0.268

Low

1260575

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1260590

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.268

Low

1260598

CFA68
Cilia- and flagella-associated protein 68

1

0

High-throughput

0.268

Low

246013

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.265

Low

966316

CAC1D
Voltage-dependent L-type calcium channel subunit alpha-1D

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024