HitPredict - High confidence protein-protein interactions

Protein: SPIKE
Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']

Gene: SPIKE, S
Organism: Severe acute respiratory syndrome coronavirus 2
Interactions: 8
UniProt ID: P0DTC2

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0019031 - viral envelope
GO:0019062 - virion attachment to host cell
GO:0019064 - fusion of virus membrane with host plasma membrane

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
517147	SPIKE Spike glycoprotein	285	1	Small-scale	0.999	High
517150	VME1 Membrane protein	4	1	Small-scale	0.680	High
517152	NCAP Nucleoprotein	4	0	Small-scale	0.663	High
517153	R1AB Replicase polyprotein 1ab	4	0	Small-scale	0.658	High
517148	AP3A ORF3a protein	2	1	Small-scale	0.595	High
517149	VEMP Envelope small membrane protein	1	1	Small-scale	0.479	High
517151	NS8 ORF8 protein	4	0	Small-scale	0.353	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025