HitPredict

Interactor 1: PTPRJ (Q12913)
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)
Gene: PTPRJ

Interactor 2: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19167335
Identification Methods	phosphatase assay
Interaction Type	dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1337 Hs			1 1484
+	Hs
		617106 PTPRG_HUMAN (757-1329): 3.11e-55: 213: 17.43		NMDE2_HUMAN (1-1484): 0: 1846: 100.00
+	Hs
		616915 PTPRB_HUMAN (463-930): 1.38e-23: 111: 16.63		NMDE2_HUMAN (1-1484): 0: 1846: 100.00
+	Hs
		441195 PTPRC_HUMAN (47-298): 3.49e-10: 67: 9.89		NMDE2_HUMAN (1-1484): 0: 1846: 100.00
+	Rn
		723631 Q66HJ7_RAT (862-1334): 3.43e-115: 382: 28.45		NMDZ1_RAT (14-940): 0: 673: 23.62
+	Hs
		616949 PTPRD_HUMAN (194-1091): 2.82e-80: 294: 12.49		GRIK1_HUMAN (13-851): 0: 719: 20.33
+	Rn
		585176 PTPRF_RAT (191-971): 2.27e-85: 310: 14.99		GRIA2_RAT (16-871): 0: 665: 20.94
+	Hs
		1060436 PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10		NMDE3_HUMAN (10-929): 0: 770: 54.01
+	Mm
		620945 PTN2_MOUSE (1033-1326): 1.44e-54: 198: 34.34		GRIA2_MOUSE (16-871): 0: 665: 20.94
+	Hs
		984265 PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10		NMDZ1_HUMAN (13-940): 0: 668: 23.60