Protein: LST8
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)

Gene: LST8, MLST8
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q9BVC4

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

787556

MTOR
Serine/threonine-protein kinase mTOR

32

14

Small-scale

0.993

High

1230035

RPTOR
Regulatory-associated protein of mTOR

16

20

Small-scale

0.982

High

1308716

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

4

3

Small-scale

0.873

High

1163832

RICTR
Rapamycin-insensitive companion of mTOR

17

5

Small-scale

0.763

High

1252041

DPTOR
DEP domain-containing mTOR-interacting protein

2

1

Small-scale

0.737

High

1313715

CLMP
CXADR-like membrane protein

2

2

High-throughput

0.726

High

943452

TCPB
T-complex protein 1 subunit beta

4

20

High-throughput

0.699

High

725542

COPB2
Coatomer subunit beta'

1

17

High-throughput

0.691

High

1313712

PDCL3
Phosducin-like protein 3

1

7

High-throughput

0.691

High

1243513

DP13B
DCC-interacting protein 13-beta

2

12

High-throughput

0.686

High

1266410

TCPW
T-complex protein 1 subunit zeta-2

3

20

High-throughput

0.667

High

1306656

TCPH
T-complex protein 1 subunit eta

3

20

High-throughput

0.667

High

1063597

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.665

High

599007

FPR1
fMet-Leu-Phe receptor

1

0

High-throughput

0.656

High

1072661

RHEB
GTP-binding protein Rheb

3

3

Small-scale

0.640

High

826860

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.628

High

172205

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.618

High

246385

SCN2B
Sodium channel subunit beta-2

1

2

High-throughput

0.618

High

311109

MPZL1
Myelin protein zero-like protein 1

1

2

High-throughput

0.618

High

903482

WDR5
WD repeat-containing protein 5

1

17

Small-scale

0.618

High

1171517

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.618

High

1281358

FBXW7
F-box/WD repeat-containing protein 7

1

18

Small-scale

0.618

High

1313714

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.618

High

781219

ETV3
ETS translocation variant 3

2

9

High-throughput

0.611

High

943753

PRAME
Melanoma antigen preferentially expressed in tumors

2

3

High-throughput

0.611

High

1021085

FOXF2
Forkhead box protein F2

2

6

High-throughput

0.611

High

1057197

MELK
Maternal embryonic leucine zipper kinase

2

2

High-throughput

0.611

High

1175151

TBA1A
Tubulin alpha-1A chain

2

16

High-throughput

0.611

High

1313709

THIC
Acetyl-CoA acetyltransferase, cytosolic

2

4

High-throughput

0.611

High

312135

LYPA2
Acyl-protein thioesterase 2

2

0

High-throughput

0.585

High

789179

HELZ
Probable helicase with zinc finger domain

1

4

High-throughput

0.575

High

1313708

LST8
Target of rapamycin complex subunit LST8

1

16

High-throughput

0.575

High

952940

PRR5
Proline-rich protein 5

1

2

Small-scale

0.554

High

793448

MUC18
Cell surface glycoprotein MUC18

1

2

Small-scale

0.553

High

1174098

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

8

High-throughput

0.553

High

868717

ATX1
Ataxin-1

1

3

High-throughput

0.541

High

415049

CDK1
Cyclin-dependent kinase 1

1

7

Small-scale

0.536

High

157137

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.536

High

164265

ZN609
Zinc finger protein 609

1

7

High-throughput

0.536

High

324596

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.536

High

504681

HSP7C
Heat shock cognate 71 kDa protein

1

9

High-throughput

0.536

High

564170

HSP76
Heat shock 70 kDa protein 6

1

10

High-throughput

0.536

High

573457

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.536

High

771020

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.536

High

821393

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.536

High

843026

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.536

High

843364

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.536

High

855723

KIF11
Kinesin-like protein KIF11

1

4

High-throughput

0.536

High

871762

HSP72
Heat shock-related 70 kDa protein 2

1

10

High-throughput

0.536

High

933591

TBA4A
Tubulin alpha-4A chain

1

16

High-throughput

0.536

High

943693

KRT85
Keratin, type II cuticular Hb5

1

5

High-throughput

0.536

High

1040950

MTMR3
Myotubularin-related protein 3

1

3

Small-scale

0.536

High

1313713

SAV1
Protein salvador homolog 1

1

4

High-throughput

0.536

High

1313717

TF7L2
Transcription factor 7-like 2

1

18

High-throughput

0.536

High

1313720

BAG5
BAG family molecular chaperone regulator 5

1

3

High-throughput

0.536

High

1313722

CHIP
E3 ubiquitin-protein ligase CHIP

1

12

High-throughput

0.536

High

1313723

RUVB1
RuvB-like 1

1

8

High-throughput

0.536

High

1295473

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

1053162

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

13

Small-scale

0.515

High

1224070

TRM2A
tRNA

1

0

High-throughput

0.513

High

1284597

VOPP1
WW domain binding protein VOPP1

1

0

High-throughput

0.513

High

1313721

TPC2L
Trafficking protein particle complex subunit 2-like protein

1

0

High-throughput

0.513

High

1306948

ANM1
Protein arginine N-methyltransferase 1

1

5

High-throughput

0.508

High

625588

CDK2
Cyclin-dependent kinase 2

1

8

Small-scale

0.501

High

850707

KS6A3
Ribosomal protein S6 kinase alpha-3

1

3

Small-scale

0.501

High

1038226

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

1

Small-scale

0.501

High

1154443

PRR5L
Proline-rich protein 5-like

1

2

Small-scale

0.500

High

50232

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.489

High

196861

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.489

High

1261542

ANR49
Ankyrin repeat domain-containing protein 49

1

4

High-throughput

0.489

High

1313725

PKHM1
Pleckstrin homology domain-containing family M member 1

1

1

Small-scale

0.489

High

1313727

NPTN
Neuroplastin

1

2

High-throughput

0.489

High

158539

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

10

Small-scale

0.479

High

163214

XPO1
Exportin-1

1

11

High-throughput

0.479

High

167609

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

9

Small-scale

0.479

High

262311

ULK1
Serine/threonine-protein kinase ULK1

1

5

Small-scale

0.479

High

833648

NUMB
Protein numb homolog

1

3

Small-scale

0.479

High

835105

TSC2
Tuberin

1

1

Small-scale

0.479

High

882535

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

8

High-throughput

0.479

High

999046

EP300
Histone acetyltransferase p300

1

12

High-throughput

0.479

High

1036862

SQSTM
Sequestosome-1

1

2

Small-scale

0.479

High

1049315

KEAP1
Kelch-like ECH-associated protein 1

1

2

High-throughput

0.479

High

1151630

OTU7B
OTU domain-containing protein 7B

1

4

Small-scale

0.479

High

1162668

LARP1
La-related protein 1

1

8

High-throughput

0.479

High

1188056

SETX
Probable helicase senataxin

1

4

High-throughput

0.479

High

1245512

ZNRF2
E3 ubiquitin-protein ligase ZNRF2

1

1

Small-scale

0.479

High

1261762

DC2I1
Cytoplasmic dynein 2 intermediate chain 1

1

14

High-throughput

0.479

High

1267537

TSC1
Hamartin

1

18

Small-scale

0.479

High

1304000

PFD5
Prefoldin subunit 5

1

8

High-throughput

0.479

High

1313710

XPO4
Exportin-4

1

12

High-throughput

0.479

High

1313716

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1313724

NUDC
Nuclear migration protein nudC

1

11

High-throughput

0.479

High

1313726

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

17

Small-scale

0.479

High

344559

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.464

High

1056119

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1168079

THADA
tRNA

1

0

High-throughput

0.458

High

1284381

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

1300636

XPO6
Exportin-6

1

0

High-throughput

0.458

High

1313711

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

Small-scale

0.458

High

1313718

S38A7
Sodium-coupled neutral amino acid transporter 7

1

0

Small-scale

0.458

High

483803

HS71B
Heat shock 70 kDa protein 1B

1

9

High-throughput

0.445

High

806994

RS9
Small ribosomal subunit protein uS4

1

4

Small-scale

0.445

High

63528

ARGFX
Arginine-fifty homeobox

1

2

High-throughput

0.437

High

639639

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.279

Low

708250

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

1236304

SERP2
Stress-associated endoplasmic reticulum protein 2

1

0

High-throughput

0.279

Low

1239821

XXLT1
Xyloside xylosyltransferase 1

1

0

High-throughput

0.279

Low

1313719

CC167
Coiled-coil domain-containing protein 167

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024