Protein: SPCS2
Signal peptidase complex subunit 2 (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit)

Gene: SPCS2, Spase25
Organism: Drosophila melanogaster
Interactions: 31
UniProt ID: Q9VYY2

Gene Ontology (top 5):
GO:0005787 - signal peptidase complex
GO:0006465 - signal peptide processing
GO:0012505 - endomembrane system
GO:0045047 - protein targeting to ER

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1487157

Q9VV76
Syntaxin 8

2

1

High-throughput

0.594

High

1191638

Q3YMT4
Signal peptidase complex catalytic subunit SEC11

1

3

High-throughput

0.575

High

1261810

Q7JRF1
RE48509p

2

0

High-throughput

0.569

High

1483380

Q9VPM9
AT02829p

2

0

High-throughput

0.569

High

1473971

Q9VFM3
IP10175p

2

2

High-throughput

0.542

High

1269394

Q7KTP4
Reticulon-like protein

1

2

High-throughput

0.494

High

1482152

Q9VMW2
Reticulon-like protein

1

2

High-throughput

0.481

High

50171

A1A6N7
IP16809p

1

1

High-throughput

0.451

High

75076

B3DND5
IP20181p

1

1

High-throughput

0.451

High

1230968

Q6AWN6
GEO12823p1

1

1

High-throughput

0.451

High

1346250

Q8T8W2
AT21555p

1

2

High-throughput

0.451

High

1470166

SPCS3
Signal peptidase complex subunit 3

1

1

High-throughput

0.445

High

68473

A8DZ13
GEO11020p1

1

1

High-throughput

0.439

High

1230975

Q6AWP0
Lifeguard, isoform A

1

2

High-throughput

0.439

High

1262079

Q7JV09
GH28348p

1

1

High-throughput

0.439

High

1488873

Q9VZR1
Phosphatidylinositol glycan anchor biosynthesis class C, isoform B

1

1

High-throughput

0.439

High

61284

A2VER2
IP18228p

2

0

High-throughput

0.310

High

357004

U729
UPF0729 protein CG18508

2

0

High-throughput

0.310

High

1069895

Q0E985
RH74701p

2

0

High-throughput

0.310

High

1263434

Q7JYX3
GEO08273p1

2

0

High-throughput

0.310

High

1305172

TMM11
Transmembrane protein 11 homolog, mitochondrial

2

0

High-throughput

0.310

High

1480896

Q9VLL8
Peritrophin-15a

2

0

High-throughput

0.310

High

1481222

Q9VLS8
LD29807p

2

0

High-throughput

0.310

High

1482876

Q9VNR8
LD47277p

2

0

High-throughput

0.310

High

1483218

Q9VPD6
BNIP3, isoform A

2

0

High-throughput

0.310

High

1484649

Q9VR57
RE18169p

2

0

High-throughput

0.310

High

1484944

Q9VRK1
GEO09627p1

2

0

High-throughput

0.310

High

1487272

Q9VVF4
FI08815p

2

0

High-throughput

0.310

High

1488872

Q9VZB5
MIP31077p

2

0

High-throughput

0.310

High

1483967

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.249

Low

1273714

Q7PLL3
Eukaryotic initiation factor 4B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025