Interactor 1: SPCS3 (Q9VCA9)
Signal peptidase complex subunit 3 (Microsomal signal peptidase 22 kDa subunit) (SPC22) (SPase 22 kDa subunit)
Gene: Spase22-23

Interactor 2: SPCS2 (Q9VYY2)
Signal peptidase complex subunit 2 (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit)
Gene: Spase25

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 38944040
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005787 - signal peptidase complex
GO:0006465 - signal peptide processing
GO:0045047 - protein targeting to ER
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 179
Dm

1 199
+ Hs

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Last updated: 11Aug2025