Protein: CENPE
Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-7) (Kinesin-related protein CENPE)

Gene: CENPE
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q02224

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
GO:0003777 - microtubule motor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

969580

CENPE
Centromere-associated protein E

2

15

Small-scale

0.743

High

236914

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

3

2

Small-scale

0.660

High

969615

NUF2
Kinetochore protein Nuf2

2

4

Small-scale

0.642

High

254580

CLAP2
CLIP-associating protein 2

2

2

High-throughput

0.628

High

209903

PRC1
Protein regulator of cytokinesis 1

2

5

Small-scale

0.624

High

308624

KI20A
Kinesin-like protein KIF20A

1

17

High-throughput

0.618

High

969587

PCM1
Pericentriolar material 1 protein

2

2

High-throughput

0.611

High

50423

SYCE3
Synaptonemal complex central element protein 3

2

0

High-throughput

0.602

High

969581

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

2

3

High-throughput

0.584

High

969605

NIN
Ninein

2

9

High-throughput

0.584

High

969582

BFSP2
Phakinin

2

2

High-throughput

0.574

High

969622

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

1

2

Small-scale

0.569

High

928879

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.561

High

176585

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.549

High

658894

MK01
Mitogen-activated protein kinase 1

1

0

Small-scale

0.537

High

127248

IPO5
Importin-5

1

2

High-throughput

0.536

High

272539

OFD1
Centriole and centriolar satellite protein OFD1

1

6

High-throughput

0.536

High

313806

SVIL
Supervillin

1

2

High-throughput

0.536

High

638494

RBTN1
Rhombotin-1

1

4

High-throughput

0.536

High

683277

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

789755

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.536

High

969584

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

4

High-throughput

0.536

High

969586

CBX2
Chromobox protein homolog 2

1

2

High-throughput

0.536

High

969588

RABE1
Rab GTPase-binding effector protein 1

1

2

High-throughput

0.536

High

969589

MARE1
Microtubule-associated protein RP/EB family member 1

1

10

High-throughput

0.536

High

969599

CLAP1
CLIP-associating protein 1

1

2

High-throughput

0.536

High

969616

P63
Tumor protein 63

1

2

Small-scale

0.536

High

969617

MED4
Mediator of RNA polymerase II transcription subunit 4

1

2

High-throughput

0.536

High

969620

CP131
Centrosomal protein of 131 kDa

1

3

High-throughput

0.536

High

147508

SOCS6
Suppressor of cytokine signaling 6

1

3

High-throughput

0.515

High

806288

RL21
Large ribosomal subunit protein eL21

1

1

High-throughput

0.515

High

969600

KTN1
Kinectin

1

3

High-throughput

0.515

High

969602

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.513

High

969604

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

475644

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

833712

CLK1
Dual specificity protein kinase CLK1

1

9

High-throughput

0.501

High

905840

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

Small-scale

0.501

High

969609

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

High-throughput

0.501

High

969618

RED2
Double-stranded RNA-specific editase B2

1

4

High-throughput

0.489

High

969583

CUL1
Cullin-1

1

5

Small-scale

0.481

High

969590

SEPT7
Septin-7

1

1

Small-scale

0.481

High

969613

DUX5
Double homeobox protein 5

1

2

High-throughput

0.481

High

969614

TRAF4
TNF receptor-associated factor 4

1

6

Small-scale

0.481

High

123238

CBX4
E3 SUMO-protein ligase CBX4

1

2

High-throughput

0.479

High

154949

NDC80
Kinetochore protein NDC80 homolog

1

5

High-throughput

0.479

High

160521

AURKA
Aurora kinase A

1

3

High-throughput

0.479

High

241506

H2B1K
Histone H2B type 1-K

1

9

High-throughput

0.479

High

386559

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

533216

PLSL
Plastin-2

1

1

High-throughput

0.479

High

640092

MOES
Moesin

1

7

High-throughput

0.479

High

792973

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

3

High-throughput

0.479

High

918300

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

High-throughput

0.479

High

969585

DCTN1
Dynactin subunit 1

1

10

High-throughput

0.479

High

969591

RBBP7
Histone-binding protein RBBP7

1

4

High-throughput

0.479

High

969594

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

969597

SYNE3
Nesprin-3

1

6

High-throughput

0.479

High

969603

MIRO2
Mitochondrial Rho GTPase 2

1

6

High-throughput

0.479

High

969607

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

969608

BICD2
Protein bicaudal D homolog 2

1

4

High-throughput

0.479

High

969611

BICD1
Protein bicaudal D homolog 1

1

4

High-throughput

0.479

High

969621

NINL
Ninein-like protein

1

6

High-throughput

0.479

High

636312

DNJB1
DnaJ homolog subfamily B member 1

1

0

Small-scale

0.460

High

130851

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

969598

DET1
DET1 homolog

1

0

High-throughput

0.458

High

969601

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

969606

NKAP
NF-kappa-B-activating protein

1

0

Small-scale

0.458

High

215075

DUX1
Double homeobox protein 1

1

2

High-throughput

0.457

High

828575

CENPF
Centromere protein F

1

7

Small-scale

0.457

High

717720

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.445

High

850004

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

7

Small-scale

0.445

High

943814

RAE1L
mRNA export factor RAE1

1

3

Small-scale

0.445

High

969593

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.445

High

969595

FBX42
F-box only protein 42

1

3

High-throughput

0.437

High

969596

SAS6
Spindle assembly abnormal protein 6 homolog

1

3

High-throughput

0.437

High

969619

HECD1
E3 ubiquitin-protein ligase HECTD1

1

5

High-throughput

0.437

High

969592

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

2

High-throughput

0.407

High

969612

NEUL4
Neuralized-like protein 4

1

1

High-throughput

0.407

High

969610

RM24
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024