Protein: CDK2
Cyclin-dependent kinase 2 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 cognate)

Gene: CDK2
Organism: Drosophila melanogaster
Interactions: 95
UniProt ID: P23573

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

618432

CCNE
G1/S-specific cyclin-E

6

20

Small-scale

0.932

High

618439

Q24159
Cyclin J

5

20

Small-scale

0.891

High

618463

Q961D1
Cyclin K, isoform A

3

20

High-throughput

0.839

High

618429

ERKA
Mitogen-activated protein kinase ERK-A

2

13

High-throughput

0.775

High

618460

CYCG
Cyclin G

2

20

Small-scale

0.775

High

618471

Q9VHN1
Cyclin-dependent kinases regulatory subunit

2

20

Small-scale

0.775

High

618446

Q7JNL9
Dacapo

2

2

Small-scale

0.757

High

618433

P91654
Cdi4

2

2

Small-scale

0.754

High

540473

CCNA
G2/mitotic-specific cyclin-A

2

20

Small-scale

0.704

High

532270

KPC3
Protein kinase C

1

6

High-throughput

0.656

High

582590

SXL
Protein sex-lethal

1

5

High-throughput

0.656

High

618425

CCNC
Cyclin-C

1

20

High-throughput

0.656

High

618450

Q7K306
Cyclin-dependent kinase 4, isoform A

1

15

High-throughput

0.656

High

618487

Q9VZP3
Cyclin J, isoform A

1

20

High-throughput

0.656

High

618449

Q7K1V0
LD39136p

1

0

High-throughput

0.622

High

283943

O76513
Cyclin-H

1

20

High-throughput

0.621

High

184388

O17144
Cyclin-H

1

20

High-throughput

0.590

High

437057

CSK2A
Casein kinase II subunit alpha

1

19

High-throughput

0.590

High

618434

P91668
Cyclin-dependent kinase inhibitor Dacapo

1

2

High-throughput

0.590

High

618437

CKS1
Cyclin-dependent kinases regulatory subunit

1

20

Small-scale

0.590

High

618438

Q24158
Cyclin D

1

20

Small-scale

0.590

High

618456

HIPPO
Serine/threonine-protein kinase hippo

1

13

High-throughput

0.590

High

618458

PUF68
Poly(U)-binding-splicing factor half pint

1

5

High-throughput

0.590

High

618486

Q9VXM1
LD22957p

1

20

High-throughput

0.590

High

618448

GLIS2
Zinc finger protein GLIS2 homolog

1

3

High-throughput

0.587

High

618472

Q9VJ42
Uncharacterized protein, isoform A

2

3

High-throughput

0.565

High

437111

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.560

High

618451

Q7K4M9
LD31969p

1

0

High-throughput

0.560

High

618457

Q8T3L3
SD01232p

1

0

High-throughput

0.560

High

54139

A1Z9G1
FI19824p1

1

6

High-throughput

0.555

High

618430

RALA
Ras-related protein Ral-a

1

7

High-throughput

0.528

High

618488

Q9W0M9
GEO12020p1

1

9

High-throughput

0.528

High

51263

GUS
Protein gustavus

1

7

High-throughput

0.508

High

80867

DIMM
Protein dimmed

1

1

High-throughput

0.508

High

428854

DFD
Homeotic protein deformed

1

8

High-throughput

0.508

High

524602

PP12
Serine/threonine-protein phosphatase alpha-2 isoform

1

13

High-throughput

0.508

High

618428

ECR
Ecdysone receptor

1

8

High-throughput

0.508

High

618442

RAD51
DNA repair protein Rad51 homolog

1

2

High-throughput

0.508

High

618461

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.508

High

618466

Q9VB23
Serine/threonine protein phosphatase 2A regulatory subunit

1

3

High-throughput

0.508

High

618476

Q9VL21
LD11652p

1

3

High-throughput

0.508

High

618477

Q9VL27
Alpha-galactosidase

1

1

High-throughput

0.508

High

618483

Q9VTX7
Eyegone, isoform A

1

9

High-throughput

0.508

High

618493

MED15
Mediator of RNA polymerase II transcription subunit 15

1

4

High-throughput

0.508

High

184161

ORC1
Origin recognition complex subunit 1

1

13

Small-scale

0.501

High

618440

ORC2
Origin recognition complex subunit 2

1

6

Small-scale

0.501

High

618459

Q8T965
Prefoldin subunit 3

1

0

High-throughput

0.486

High

618468

Q9VED4
MIP30824p1

1

0

High-throughput

0.486

High

618481

FRY
Protein furry

1

0

High-throughput

0.486

High

81176

B7YZX6
Uncharacterized protein, isoform B

1

5

High-throughput

0.481

High

111967

L0MPR7
Twin of eyeless, isoform C

1

9

High-throughput

0.481

High

618489

Q9W1H7
Putative homeodomain protein

1

5

High-throughput

0.481

High

618494

X2JLM6
Ubiquitin carboxyl-terminal hydrolase

1

6

High-throughput

0.481

High

618447

Q7JVY2
Double parked, isoform A

1

4

Small-scale

0.479

High

220894

PGAM5
Serine/threonine-protein phosphatase Pgam5, mitochondrial

1

1

High-throughput

0.464

High

618462

HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.464

High

618467

Q9VC60
BUD13 homolog

1

4

High-throughput

0.464

High

618478

POLZ2
DNA polymerase zeta subunit 2

1

1

High-throughput

0.464

High

618436

STAT
Signal transducer and transcription activator

1

0

Small-scale

0.458

High

186188

GBLP
Small ribosomal subunit protein RACK1

1

13

High-throughput

0.457

High

283686

O76136
Homeodomain protein

1

9

High-throughput

0.457

High

283906

RAD54
DNA repair and recombination protein RAD54-like

1

2

High-throughput

0.457

High

612559

DDX6
ATP-dependent RNA helicase me31b

1

8

High-throughput

0.457

High

618427

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.457

High

618431

PRS4
26S proteasome regulatory subunit 4

1

6

High-throughput

0.457

High

618443

NLP
Nucleoplasmin-like protein

1

3

High-throughput

0.457

High

618454

UBP2
Ubiquitin carboxyl-terminal hydrolase Usp2

1

5

High-throughput

0.457

High

618465

Q9V490
GH14454p

1

10

High-throughput

0.457

High

618469

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.457

High

618473

Q9VJZ6
LD40224p

1

6

High-throughput

0.457

High

618479

Q9VRS0
Importin subunit alpha

1

5

High-throughput

0.457

High

618482

ULA1
Nedd8-activating enzyme E1 regulatory subunit

1

2

High-throughput

0.457

High

618491

MYC
Myc protein

1

5

High-throughput

0.457

High

91172

E3CTS2
MIP27658p

1

3

High-throughput

0.439

High

115555

M9PFH3
Uncharacterized protein, isoform D

1

1

High-throughput

0.439

High

618426

XPA
DNA repair protein complementing XP-A cells homolog

1

0

High-throughput

0.438

High

618435

Q24036
Failed axon connections protein

1

0

High-throughput

0.438

High

618445

Y1411
WD repeat-containing protein CG11141

1

0

High-throughput

0.438

High

618464

FADD
Fas-associated death domain protein

1

0

High-throughput

0.438

High

618490

Q9W1L8
GH11818p

1

0

High-throughput

0.438

High

618452

Q7YZ95
S-phase kinase-associated protein 2, isoform A

1

6

Small-scale

0.437

High

283992

O76523
Mitotic checkpoint control protein

1

14

High-throughput

0.417

High

618444

Q5U0Z2
LD30448p

1

1

High-throughput

0.417

High

618453

Q8IGS9
U6 snRNA-associated Sm-like protein LSm4

1

3

High-throughput

0.417

High

618455

Q8SYU4
RE33778p

1

3

High-throughput

0.417

High

618475

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

3

High-throughput

0.417

High

618484

Q9VU23
Uncharacterized protein, isoform E

1

1

High-throughput

0.417

High

618492

Q9Y138
BcDNA.GH06193

1

6

High-throughput

0.417

High

618441

RBF
Retinoblastoma family protein

1

11

High-throughput

0.381

High

526585

VTU2
Vitelline membrane protein Vm26Ab

1

0

High-throughput

0.265

Low

618470

Q9VH02
LD30822p

1

0

High-throughput

0.265

Low

618474

Q9VKF2
RE59904p

1

0

High-throughput

0.265

Low

618485

Q9VWT7
GEO07745p1

1

0

High-throughput

0.265

Low

220990

O46100
EG:8D8.3 protein

1

0

High-throughput

0.238

Low

618480

Q9VSF5
GH02649p

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024