HitPredict

Interactor 1: DJC10 (Q8IXB1)
DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr)
Gene: DNAJC10

Interactor 2: CALR3 (Q96L12)
Calreticulin-3 (Calreticulin-2) (Calsperin)
Gene: CALR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0036503 - ERAD pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 793 Hs			1 384
+	Hs
		653650 DJC10_HUMAN (1-793): 0: 609: 100.00		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Hs
		654519 DJC10_HUMAN (1-793): 0: 609: 100.00		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73
+	Hs
		1067796 PDIA6_HUMAN (135-451): 3.77e-40: 155: 16.62		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		531950 PDIA4_HUMAN (153-643): 4.32e-35: 143: 13.67		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		671897 PDIA3_HUMAN (235-674): 4.71e-27: 118: 13.24		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		1296660 DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		1240407 TXND5_HUMAN (687-793): 2.4e-20: 96.6: 25.00		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		653597 PDIA6_HUMAN (135-451): 3.77e-40: 155: 16.62		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Hs
		654915 DJC16_HUMAN (18-249): 6.4e-64: 230: 30.83		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73
+	Hs
		531728 PDIA4_HUMAN (153-643): 4.32e-35: 143: 13.67		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Hs
		653491 PDIA3_HUMAN (235-674): 4.71e-27: 118: 13.24		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Dm
		667040 PDIA6_DROME (123-353): 1.68e-36: 144: 21.40		CALR_DROME (8-365): 2.58e-144: 417: 41.56
+	Hs
		653761 DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Dm
		667013 PDI_DROME (243-661): 1.15e-22: 104: 12.44		CALR_DROME (8-365): 2.58e-144: 417: 41.56
+	Hs
		531729 PDIA4_HUMAN (153-643): 4.32e-35: 143: 13.67		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73
+	Dm
		667020 Q3YMU0_DROME (229-644): 3.21e-18: 90.4: 12.39		CALR_DROME (8-365): 2.58e-144: 417: 41.56
+	Dm
		1359553 PDIA6_DROME (123-353): 1.68e-36: 144: 21.40		Q9VAL7_DROME (22-355): 4.6e-120: 362: 26.51
+	Hs
		654099 PDIA3_HUMAN (235-674): 4.71e-27: 118: 13.24		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73
+	Rn
		514119 PDIA3_RAT (236-674): 2.15e-25: 112: 12.92		CALX_RAT (16-357): 1.96e-122: 367: 26.97
+	Hs
		654870 DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73