Protein: T2EB
Transcription initiation factor IIE subunit beta (TFIIE-beta) (General transcription factor IIE subunit 2)

Gene: T2EB, GTF2E2
Organism: Homo sapiens
Interactions: 153
UniProt ID: P29084

Gene Ontology (top 5):
GO:0001097 - TFIIH-class transcription factor complex binding
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

663996

T2EA
General transcription factor IIE subunit 1

11

6

Small-scale

0.981

High

534067

T2FB
General transcription factor IIF subunit 2

1

1

Small-scale

0.647

High

664066

VIGLN
Vigilin

3

0

High-throughput

0.638

High

664047

FEN1
Flap endonuclease 1

2

1

High-throughput

0.628

High

664136

RBM12
RNA-binding protein 12

2

1

High-throughput

0.628

High

664142

DBNL
Drebrin-like protein

2

1

High-throughput

0.628

High

664041

T2EB
Transcription initiation factor IIE subunit beta

1

0

Small-scale

0.614

High

664046

T2FA
General transcription factor IIF subunit 1

2

1

Small-scale

0.602

High

204296

MS18B
Protein Mis18-beta

2

0

High-throughput

0.602

High

213802

SYNC
Asparagine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.602

High

274329

WDHD1
WD repeat and HMG-box DNA-binding protein 1

2

0

High-throughput

0.602

High

275984

EIF3J
Eukaryotic translation initiation factor 3 subunit J

2

0

High-throughput

0.602

High

447733

THIK
3-ketoacyl-CoA thiolase, peroxisomal

2

0

High-throughput

0.602

High

664042

TPP2
Tripeptidyl-peptidase 2

2

0

High-throughput

0.602

High

664044

BLVRB
Flavin reductase

2

0

High-throughput

0.602

High

664048

EFTS
Elongation factor Ts, mitochondrial

2

0

High-throughput

0.602

High

664052

GUAA
GMP synthase [glutamine-hydrolyzing]

2

0

High-throughput

0.602

High

664058

SYYC
Tyrosine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.602

High

664060

ERF1
Eukaryotic peptide chain release factor subunit 1

2

0

High-throughput

0.602

High

664065

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

2

0

High-throughput

0.602

High

664072

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

0

High-throughput

0.602

High

664075

PP1R8
Nuclear inhibitor of protein phosphatase 1

2

0

High-throughput

0.602

High

664076

CSTF3
Cleavage stimulation factor subunit 3

2

0

High-throughput

0.602

High

664081

MDC1
Mediator of DNA damage checkpoint protein 1

2

0

High-throughput

0.602

High

664082

PSF1
DNA replication complex GINS protein PSF1

2

0

High-throughput

0.602

High

664086

PMVK
Phosphomevalonate kinase

2

0

High-throughput

0.602

High

664089

TOM34
Mitochondrial import receptor subunit TOM34

2

0

High-throughput

0.602

High

664094

CAF17
Putative transferase CAF17, mitochondrial

2

0

High-throughput

0.602

High

664095

BRE1A
E3 ubiquitin-protein ligase BRE1A

2

0

High-throughput

0.602

High

664107

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

2

0

High-throughput

0.602

High

664117

DNJC2
DnaJ homolog subfamily C member 2

2

0

High-throughput

0.602

High

664118

VRK1
Serine/threonine-protein kinase VRK1

2

0

High-throughput

0.602

High

664119

PYM1
Partner of Y14 and mago

2

0

High-throughput

0.602

High

664122

PDC10
Programmed cell death protein 10

2

0

High-throughput

0.602

High

664124

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

2

0

High-throughput

0.602

High

664127

SLK
STE20-like serine/threonine-protein kinase

2

0

High-throughput

0.602

High

664130

UBE2T
Ubiquitin-conjugating enzyme E2 T

2

0

High-throughput

0.602

High

664134

PHP14
14 kDa phosphohistidine phosphatase

2

0

High-throughput

0.602

High

664135

SYFB
Phenylalanine--tRNA ligase beta subunit

2

0

High-throughput

0.602

High

664139

MS18A
Protein Mis18-alpha

2

0

High-throughput

0.602

High

664143

MCTS1
Malignant T-cell-amplified sequence 1

2

0

High-throughput

0.602

High

664147

SBDS
Ribosome maturation protein SBDS

2

0

High-throughput

0.602

High

664149

TLN1
Talin-1

2

0

High-throughput

0.602

High

664150

PPME1
Protein phosphatase methylesterase 1

2

0

High-throughput

0.602

High

664151

SNX5
Sorting nexin-5

2

0

High-throughput

0.602

High

664055

CDK7
Cyclin-dependent kinase 7

2

1

Small-scale

0.595

High

664067

TF2B
Transcription initiation factor IIB

2

1

Small-scale

0.595

High

664104

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.580

High

664110

KAT5
Histone acetyltransferase KAT5

2

0

High-throughput

0.580

High

664133

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

394168

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.577

High

589789

TBP
TATA-box-binding protein

2

0

Small-scale

0.577

High

664057

TF2AA
Transcription initiation factor IIA subunit 1

2

0

Small-scale

0.577

High

646369

KAD4
Adenylate kinase 4, mitochondrial

2

1

High-throughput

0.574

High

664071

EF1A2
Elongation factor 1-alpha 2

2

1

High-throughput

0.574

High

664091

ACTBL
Beta-actin-like protein 2

2

1

High-throughput

0.574

High

664126

EIF2A
Eukaryotic translation initiation factor 2A

2

1

High-throughput

0.574

High

617437

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.558

High

369039

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

340791

KAD1
Adenylate kinase isoenzyme 1

1

1

High-throughput

0.536

High

545763

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

1

High-throughput

0.536

High

664070

CSTF1
Cleavage stimulation factor subunit 1

1

1

High-throughput

0.536

High

664152

TACC3
Transforming acidic coiled-coil-containing protein 3

1

1

High-throughput

0.536

High

48095

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

0

High-throughput

0.513

High

242671

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.513

High

271471

LYPA1
Acyl-protein thioesterase 1

1

0

High-throughput

0.513

High

274064

XRP2
Protein XRP2

1

0

High-throughput

0.513

High

307770

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

1

0

High-throughput

0.513

High

508353

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

566297

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.513

High

664045

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.513

High

664056

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.513

High

664078

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.513

High

664087

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

664090

UGPA
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.513

High

664105

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.513

High

664111

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.513

High

664115

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.513

High

664120

SLD5
DNA replication complex GINS protein SLD5

1

0

High-throughput

0.513

High

664121

PSF3
DNA replication complex GINS protein PSF3

1

0

High-throughput

0.513

High

664125

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

664132

LZTL1
Leucine zipper transcription factor-like protein 1

1

0

High-throughput

0.513

High

664144

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

0

High-throughput

0.513

High

664145

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.513

High

664146

CAB39
Calcium-binding protein 39

1

0

High-throughput

0.513

High

345342

FOS
Protein c-Fos

1

1

Small-scale

0.501

High

584553

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

1

Small-scale

0.501

High

559566

H12
Histone H1.2

1

0

High-throughput

0.493

High

664074

GRSF1
G-rich sequence factor 1

1

1

Small-scale

0.481

High

401475

JUN
Transcription factor Jun

1

0

Small-scale

0.480

High

612463

XPA
DNA repair protein complementing XP-A cells

1

0

Small-scale

0.480

High

664068

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.480

High

664079

KLF5
Krueppel-like factor 5

1

0

Small-scale

0.480

High

664099

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

Small-scale

0.480

High

437916

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

624780

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.479

High

664043

PML
Protein PML

1

1

High-throughput

0.479

High

664050

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

664062

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

664097

MCAF1
Activating transcription factor 7-interacting protein 1

1

2

Small-scale

0.479

High

124772

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

Small-scale

0.458

High

243982

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

295944

MTA2
Metastasis-associated protein MTA2

1

0

High-throughput

0.458

High

304038

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.458

High

373734

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

453169

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

518824

TPR
Nucleoprotein TPR

1

0

High-throughput

0.458

High

523540

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

664049

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

664054

DYN2
Dynamin-2

1

0

High-throughput

0.458

High

664059

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

0

High-throughput

0.458

High

664061

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

664063

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

664064

H31
Histone H3.1

1

0

High-throughput

0.458

High

664077

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

664085

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

664101

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

664103

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

664109

DNJC9
DnaJ homolog subfamily C member 9

1

0

High-throughput

0.458

High

664112

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

664113

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.458

High

664116

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

664123

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

664131

BRD7
Bromodomain-containing protein 7

1

0

High-throughput

0.458

High

664138

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

664140

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

664148

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

664092

HS904
Putative heat shock protein HSP 90-alpha A4

1

2

High-throughput

0.445

High

664102

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

664084

CASP8
Caspase-8

1

0

High-throughput

0.426

High

2137

GAL3B
Putative glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial

1

1

High-throughput

0.407

High

484547

GAL3A
Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial

1

1

High-throughput

0.407

High

178405

STX7
Syntaxin-7

2

0

High-throughput

0.328

High

664083

MESD
LRP chaperone MESD

2

0

High-throughput

0.328

High

664096

HIBCH
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

2

0

High-throughput

0.328

High

664100

HDGR2
Hepatoma-derived growth factor-related protein 2

2

0

High-throughput

0.328

High

664114

EFHD2
EF-hand domain-containing protein D2

2

0

High-throughput

0.328

High

664128

LRC40
Leucine-rich repeat-containing protein 40

2

0

High-throughput

0.328

High

664137

CYRIB
CYFIP-related Rac1 interactor B

2

0

High-throughput

0.328

High

664141

CHRD1
Cysteine and histidine-rich domain-containing protein 1

2

0

High-throughput

0.328

High

276426

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.279

Low

664053

GBG10

1

0

High-throughput

0.279

Low

664073

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.279

Low

664088

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

0

High-throughput

0.279

Low

664093

MTX3
Metaxin-3

1

0

High-throughput

0.279

Low

664108

SPRY4
SPRY domain-containing protein 4

1

0

High-throughput

0.279

Low

664129

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

664051

ARL4D
ADP-ribosylation factor-like protein 4D

1

0

High-throughput

0.249

Low

664098

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

664106

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.249

Low

664069

TAGL
Transgelin

1

0

High-throughput

0.232

Low

664080

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024