Protein: Q9XYZ4
Double-strand break repair protein

Gene: Q9XYZ4, mre11
Organism: Drosophila melanogaster
Interactions: 50
UniProt ID: Q9XYZ4

Gene Ontology (top 5):
GO:0000014 - single-stranded DNA endodeoxyribonuclease activity
GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0007095 - mitotic G2 DNA damage checkpoint signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1489711

RAD50
DNA repair protein RAD50

4

6

Small-scale

0.892

High

1470135

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.625

High

120241

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

2

High-throughput

0.528

High

1475331

Q9VGW7
type I protein arginine methyltransferase

1

1

Small-scale

0.512

High

609168

CRN
Protein crooked neck

1

1

High-throughput

0.494

High

1343211

BICDR
Bicaudal D-related protein homolog

1

1

High-throughput

0.494

High

1472825

Q9VEH3
Uncharacterized protein, isoform A

1

2

High-throughput

0.494

High

1204144

ATM
Serine/threonine-protein kinase ATM

1

6

Small-scale

0.479

High

1475173

TCTP
Translationally-controlled tumor protein homolog

1

1

Small-scale

0.479

High

426876

HP1
Heterochromatin protein 1

1

0

Small-scale

0.458

High

1485950

Q9VT40
Nibrin

1

2

Small-scale

0.445

High

62811

A4UZL3
Eps15 homology domain containing protein-binding protein 1, isoform F

1

1

High-throughput

0.439

High

68229

A8DYA3
Toutatis, isoform E

1

7

High-throughput

0.439

High

121064

M9PEP8
Muscle-specific protein 300 kDa, isoform M

1

1

High-throughput

0.439

High

121636

M9PFR8
Artemis, isoform B

1

1

High-throughput

0.439

High

1207942

Q5KTT4
Eukaryotic translation initiation factor 4 gamma 2

1

1

High-throughput

0.439

High

1269279

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

1

High-throughput

0.439

High

1469838

Q9VC05
Oxysterol-binding protein

1

1

High-throughput

0.439

High

1474083

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

1

1

High-throughput

0.439

High

197676

O18397
Oxysterol-binding protein

1

1

High-throughput

0.417

High

1069950

Q0E996
Eukaryotic translation initiation factor 4 gamma 2

1

1

High-throughput

0.417

High

1321057

Q8MR93
SD05215p

1

1

High-throughput

0.417

High

1321483

Q8MSW1
LD26904p

1

1

High-throughput

0.417

High

1343668

Q8SXA8
GH18470p

1

1

High-throughput

0.417

High

1409476

Q9BMQ0
Toutatis

1

7

High-throughput

0.417

High

1479186

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

1

High-throughput

0.417

High

1487172

Q9VV82
Artemis, isoform A

1

1

High-throughput

0.417

High

1489154

Q9VZU6
BTB-VII protein domain

1

1

High-throughput

0.417

High

53086

A1Z7K2
FI03455p

1

1

High-throughput

0.407

High

1473001

FLNA
Filamin-A

1

1

High-throughput

0.407

High

653068

HMOC
Homeotic protein ocelliless

1

0

High-throughput

0.282

High

1032737

GCL
Protein germ cell-less

1

0

High-throughput

0.282

High

1171640

SNAP
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.282

High

1457845

SPIR
Protein spire

1

0

High-throughput

0.282

High

1463232

Q9V3B8
LD18634p

1

0

High-throughput

0.282

High

1485426

AKIRN
Akirin

1

0

High-throughput

0.282

High

1485981

CANB
Calpain-B

1

0

High-throughput

0.282

High

1488612

Q9VY91
Programmed cell death protein 4

1

0

High-throughput

0.282

High

1273629

Q7PL26
Repressor of RNA polymerase III transcription MAF1

1

0

High-throughput

0.251

Low

1466439

Q9V7W9
Nuclear inhibitor of protein phosphatase 1

1

0

High-throughput

0.251

Low

1489665

Q9W1Z4
Uncharacterized protein, isoform D

1

0

High-throughput

0.251

Low

1377589

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low

1469762

DANR
Protein distal antenna-related

1

0

High-throughput

0.238

Low

1264018

Q7K0D3
CG12909 protein

1

0

High-throughput

0.232

Low

1480573

Q9VL93
GEO07195p1

1

0

High-throughput

0.232

Low

1481571

Q9VM72
RNA polymerase I subunit F

1

0

High-throughput

0.232

Low

1484929

Q9VRJ4
Dehydrogenase/reductase 4

1

0

High-throughput

0.232

Low

1487548

Q9VW10
LD21924p

1

0

High-throughput

0.232

Low

1487771

Y4230
Probable RNA-binding protein CG14230

1

0

High-throughput

0.232

Low

1489401

Q9W0L7
ubiquitinyl hydrolase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025