Interactor 1: RAD50 (Q9W252)
DNA repair protein RAD50 (EC 3.6.-.-)
Gene: RAD50
Interactor 2: Q9XYZ4 (Q9XYZ4)
Double-strand break repair protein
Gene: mre11
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 1.00 | 0.892 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19520832, 25588834, 15710747, 38944040 |
| Identification Methods | affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, two hybrid fragment pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA_23~Metallophos, AAA_23~Mre11_DNA_bind, Metallophos~SbcC_Walker_B |
| Common GO terms | GO:0000723 - telomere maintenance GO:0030870 - Mre11 complex GO:0051276 - chromosome organization |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
