Protein: KU70
ATP-dependent DNA helicase 2 subunit 1 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit dp70) (ATP-dependent helicase Irbp) (Inverted repeat-binding protein) (Yolk protein factor 1 subunit beta)

Gene: KU70, Irbp
Organism: Drosophila melanogaster
Interactions: 56
UniProt ID: Q23976

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0003684 - damaged DNA binding
GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

773360

RFC1
Replication factor C subunit 1

2

13

High-throughput

0.737

High

777353

PARP
Poly [ADP-ribose] polymerase

2

9

High-throughput

0.737

High

1171486

Q9I7M8
ATP-dependent DNA helicase II subunit 2

2

8

High-throughput

0.737

High

1171506

Q9VYA5
DNA ligase 4

2

6

High-throughput

0.737

High

916489

RFC2
Replication factor C subunit 2

2

7

High-throughput

0.571

High

1171495

Q9VIH1
CG9273 protein

2

5

High-throughput

0.571

High

1171497

Q9VKW3
Activator 1 subunit 5

2

7

High-throughput

0.571

High

1171504

Q9VX15
Replication factor C subunit 2

2

7

High-throughput

0.571

High

1171507

Q9VYW3
GEO08380p1

2

1

High-throughput

0.571

High

1171509

Q9W140
Regulatory protein zeste

2

1

High-throughput

0.571

High

559131

ELF1
Protein grainyhead

1

4

High-throughput

0.541

High

1171512

CXXC1
CXXC-type zinc finger protein 1

1

4

High-throughput

0.541

High

355760

O96378
RE17884p

2

4

High-throughput

0.521

High

1055197

AL
Homeobox protein aristaless

2

6

High-throughput

0.521

High

1171485

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

3

High-throughput

0.481

High

838587

TTKA
Protein tramtrack, alpha isoform

1

7

High-throughput

0.479

High

942039

OTP
Homeobox protein orthopedia

1

6

High-throughput

0.479

High

1171473

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

1171490

Q9U9Q1
Replication factor C subunit 3

1

7

High-throughput

0.479

High

1171513

Q9XTL2
Jak pathway signal transduction adaptor molecule

1

1

High-throughput

0.464

High

1171488

Q9I7T8
PAN2-PAN3 deadenylation complex subunit PAN3

1

1

High-throughput

0.457

High

1171475

XPC
DNA repair protein complementing XP-C cells homolog

1

7

High-throughput

0.445

High

1171477

Q7JNE1
Regulatory protein zeste

1

1

High-throughput

0.445

High

1171481

Q8IRL9
DNA replication ATP-dependent helicase/nuclease

1

1

High-throughput

0.445

High

1171494

INO80
Chromatin-remodeling ATPase INO80

1

7

High-throughput

0.445

High

1171498

Q9VMS4
GH23983p

1

6

High-throughput

0.445

High

1171501

Q9VSZ2
RE59279p

1

1

High-throughput

0.445

High

118378

M9NE09
Uncharacterized protein, isoform E

1

3

High-throughput

0.439

High

1070152

Q0E9N3
Lethal

1

1

High-throughput

0.439

High

1171505

RG190
Rho GTPase-activating protein 190

1

4

High-throughput

0.439

High

1171478

Q7YZ91
RT01013p

1

1

High-throughput

0.437

High

1171479

Q86BR8
Mitochondrial transcription factor A, isoform B

1

8

High-throughput

0.437

High

1171503

Q9VWS7
MIP23504p

1

1

High-throughput

0.437

High

1171511

Q9W2P8
Homeobrain

1

6

High-throughput

0.437

High

1171482

Q8MT69
LP10790p

1

1

High-throughput

0.417

High

1171491

Q9V9A9
L(2)01289 long form

1

1

High-throughput

0.417

High

1171508

Q9VZU6
BTB-VII protein domain

1

6

High-throughput

0.417

High

55224

A1Z995
Sequoia, isoform A

1

2

High-throughput

0.407

High

118094

M9MSJ7
Uncharacterized protein, isoform C

1

1

High-throughput

0.407

High

627200

DLL
Homeotic protein distal-less

1

8

High-throughput

0.407

High

1171474

NETB
Netrin-B

1

1

High-throughput

0.407

High

1171483

Q8SZT1
GH27708p

1

8

High-throughput

0.407

High

1171493

Q9VDL2
LD40493p

1

8

High-throughput

0.407

High

1171496

Q9VJC1
GH17679p

1

2

High-throughput

0.407

High

1171499

Q9VQJ7
LD40940p

1

1

High-throughput

0.407

High

1171500

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.407

High

756773

FAS2
Fasciclin-2

2

0

High-throughput

0.328

High

1171480

Q8IQD8
Phospholipid scramblase

1

0

High-throughput

0.282

High

1171489

Q9NCC3
Sorting nexin

1

0

High-throughput

0.282

High

1171492

Q9VDB7
Argus, isoform A

1

0

High-throughput

0.282

High

1171487

Q9I7P3
BBSome complex member BBS5

1

0

High-throughput

0.265

Low

1171502

FRY
Protein furry

1

0

High-throughput

0.265

Low

1171476

Q4QPP9
GH02096p

1

0

High-throughput

0.249

Low

1171484

Q8T3N5
GM05133p

1

0

High-throughput

0.238

Low

1069608

Q0E8V7
Mitochondrial import inner membrane translocase subunit

1

0

High-throughput

0.232

Low

1171510

Q9W258
Babos, isoform A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025