Protein: Q9I7M8
ATP-dependent DNA helicase II subunit 2 (EC 3.6.4.12)

Gene: Q9I7M8, Ku80
Organism: Drosophila melanogaster
Interactions: 39
UniProt ID: Q9I7M8

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0003684 - damaged DNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0006303 - double-strand break repair via nonhomologous end joining

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

773381

RFC1
Replication factor C subunit 1

2

13

High-throughput

0.737

High

1171486

KU70
ATP-dependent DNA helicase 2 subunit 1

2

8

High-throughput

0.737

High

1440478

Q9VYA5
DNA ligase 4

2

6

High-throughput

0.737

High

777357

PARP
Poly [ADP-ribose] polymerase

2

9

High-throughput

0.659

High

916497

RFC2
Replication factor C subunit 2

2

7

High-throughput

0.571

High

1175679

XPC
DNA repair protein complementing XP-C cells homolog

2

7

High-throughput

0.571

High

1440469

Q9U9Q1
Replication factor C subunit 3

2

7

High-throughput

0.571

High

1440471

Q9VIH1
CG9273 protein

2

5

High-throughput

0.571

High

1440473

Q9VKW3
Activator 1 subunit 5

2

7

High-throughput

0.571

High

1440477

Q9VX15
Replication factor C subunit 2

2

7

High-throughput

0.571

High

1440479

Q9VYW3
GEO08380p1

2

1

High-throughput

0.571

High

355764

O96378
RE17884p

2

4

High-throughput

0.521

High

1055201

AL
Homeobox protein aristaless

2

6

High-throughput

0.521

High

1440480

Q9W140
Regulatory protein zeste

2

1

High-throughput

0.521

High

1174411

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

836512

DEI
Helix-loop-helix protein delilah

1

2

High-throughput

0.464

High

1306586

Q8IRL9
DNA replication ATP-dependent helicase/nuclease

1

1

High-throughput

0.445

High

1440475

Q9VSZ2
RE59279p

1

1

High-throughput

0.445

High

451815

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

3

High-throughput

0.439

High

612460

TLL
Protein tailless

1

12

High-throughput

0.437

High

614875

EMS
Homeotic protein empty spiracles

1

6

High-throughput

0.437

High

838613

TTKA
Protein tramtrack, alpha isoform

1

7

High-throughput

0.437

High

942054

OTP
Homeobox protein orthopedia

1

6

High-throughput

0.437

High

1285754

Q86BR8
Mitochondrial transcription factor A, isoform B

1

8

High-throughput

0.437

High

1344926

Q8SZT1
GH27708p

1

8

High-throughput

0.437

High

1440472

Q9VJC1
GH17679p

1

2

High-throughput

0.437

High

1440476

Q9VWS7
MIP23504p

1

1

High-throughput

0.437

High

1440481

Q9W2P8
Homeobrain

1

6

High-throughput

0.437

High

1275070

Q7YSQ1
Notch

1

4

High-throughput

0.417

High

118101

M9MSJ7
Uncharacterized protein, isoform C

1

1

High-throughput

0.407

High

608045

TTKB
Protein tramtrack, beta isoform

1

11

High-throughput

0.407

High

627224

DLL
Homeotic protein distal-less

1

8

High-throughput

0.407

High

1175030

NETB
Netrin-B

1

1

High-throughput

0.407

High

1261166

Q7JNE1
Regulatory protein zeste

1

1

High-throughput

0.407

High

1268754

LOLAL
Longitudinals lacking protein-like

1

6

High-throughput

0.407

High

1440470

Q9VDL2
LD40493p

1

8

High-throughput

0.407

High

1440474

Q9VQJ7
LD40940p

1

1

High-throughput

0.407

High

431633

ADF1
Transcription factor Adf-1

1

0

High-throughput

0.249

Low

1377325

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025