Protein: MAPK3
MAP kinase-activated protein kinase 3 (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAP-K3) (MAPKAPK-3) (MK-3) (EC 2.7.11.1) (Chromosome 3p kinase) (3pK)

Gene: MAPK3, MAPKAPK3
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q16644

Gene Ontology (top 5):
GO:0002224 - toll-like receptor signaling pathway
GO:0004674 - protein serine/threonine kinase activity
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1082559

MK14
Mitogen-activated protein kinase 14

16

20

Small-scale

0.988

High

1078190

MK11
Mitogen-activated protein kinase 11

7

20

High-throughput

0.969

High

824642

MAPK2
MAP kinase-activated protein kinase 2

2

17

High-throughput

0.811

High

1085117

PHC2
Polyhomeotic-like protein 2

1

4

Small-scale

0.713

High

217892

PRKY
Putative serine/threonine-protein kinase PRKY

2

12

High-throughput

0.712

High

1085120

SCYL1
N-terminal kinase-like protein

1

5

High-throughput

0.691

High

895099

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.656

High

942689

SRPK2
SRSF protein kinase 2

1

14

High-throughput

0.647

High

56534

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

4

High-throughput

0.618

High

1085114

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.618

High

388473

HSPB1
Heat shock protein beta-1

2

10

Small-scale

0.602

High

160595

AURKA
Aurora kinase A

1

14

High-throughput

0.590

High

211021

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

18

High-throughput

0.590

High

338488

EGFR
Epidermal growth factor receptor

1

7

High-throughput

0.590

High

348689

RASN
GTPase NRas

1

4

High-throughput

0.590

High

523007

SRC
Proto-oncogene tyrosine-protein kinase Src

1

7

High-throughput

0.590

High

542887

BRAF
Serine/threonine-protein kinase B-raf

1

8

High-throughput

0.590

High

793641

DCC
Netrin receptor DCC

1

1

High-throughput

0.590

High

1079078

STK11
Serine/threonine-protein kinase STK11

1

11

High-throughput

0.590

High

203135

P52K
52 kDa repressor of the inhibitor of the protein kinase

1

1

Small-scale

0.552

High

551534

TFE2
Transcription factor E2-alpha

1

1

Small-scale

0.549

High

319855

HERC2
E3 ubiquitin-protein ligase HERC2

1

6

High-throughput

0.536

High

968783

MEF2A
Myocyte-specific enhancer factor 2A

1

1

High-throughput

0.536

High

1085112

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.513

High

879115

SUMO3
Small ubiquitin-related modifier 3

1

4

High-throughput

0.508

High

1079991

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.508

High

394795

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

579142

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

9

Small-scale

0.501

High

808145

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

6

High-throughput

0.501

High

1054140

BECN1
Beclin-1

1

1

Small-scale

0.501

High

1085113

CPZIP
CapZ-interacting protein

1

1

Small-scale

0.501

High

1085121

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

5

High-throughput

0.501

High

856181

SPSY
Spermine synthase

1

0

High-throughput

0.486

High

1085115

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.486

High

651329

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

717871

BMI1
Polycomb complex protein BMI-1

1

3

Small-scale

0.479

High

719343

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

5

High-throughput

0.479

High

873130

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

7

High-throughput

0.479

High

1069848

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

7

High-throughput

0.479

High

1085116

TAXB1
Tax1-binding protein 1

1

2

High-throughput

0.479

High

1085123

RING2
E3 ubiquitin-protein ligase RING2

1

3

Small-scale

0.479

High

1085119

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.457

High

1085122

RHG07
Rho GTPase-activating protein 7

1

5

High-throughput

0.457

High

414303

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.438

High

1085118

ARF
Tumor suppressor ARF

1

0

High-throughput

0.438

High

353940

IGHM
Immunoglobulin heavy constant mu

1

2

High-throughput

0.417

High

521966

CADH1
Cadherin-1

1

1

High-throughput

0.417

High

1069587

PGFRL
Platelet-derived growth factor receptor-like protein

1

2

High-throughput

0.417

High


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Last updated: 15 Jul 2024