Protein: 2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha)

Gene: 2ABA, PPP2R2A
Organism: Homo sapiens
Interactions: 219
UniProt ID: P63151

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006470 - protein dephosphorylation
GO:0019888 - protein phosphatase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672076

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

17

10

Small-scale

0.765

High

927793

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

12

20

Small-scale

0.762

High

915156

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

8

20

High-throughput

0.756

High

672400

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

6

10

Small-scale

0.737

High

927831

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

4

7

High-throughput

0.702

High

927871

CDCA4
Cell division cycle-associated protein 4

4

9

High-throughput

0.702

High

56526

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

4

7

High-throughput

0.699

High

927857

PBIR1
PPP2R1A-PPP2R2A-interacting phosphatase regulator 1

4

6

High-throughput

0.699

High

927868

IER2
Immediate early response gene 2 protein

3

8

High-throughput

0.667

High

528940

CFTR
Cystic fibrosis transmembrane conductance regulator

3

2

High-throughput

0.650

High

927883

SRTD4
SERTA domain-containing protein 4

4

3

High-throughput

0.638

High

927803

FOXC1
Forkhead box protein C1

2

15

High-throughput

0.628

High

927867

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

2

2

High-throughput

0.628

High

786924

MTREX
Exosome RNA helicase MTR4

2

5

High-throughput

0.621

High

927910

RBM7
RNA-binding protein 7

2

8

High-throughput

0.621

High

862020

DAPK1
Death-associated protein kinase 1

2

1

Small-scale

0.620

High

927809

CUL3
Cullin-3

2

4

High-throughput

0.611

High

927846

FXL16
F-box/LRR-repeat protein 16

2

3

Small-scale

0.611

High

927850

COP1
E3 ubiquitin-protein ligase COP1

2

3

High-throughput

0.611

High

927866

FOXC2
Forkhead box protein C2

2

15

Small-scale

0.611

High

927899

HDAC5
Histone deacetylase 5

2

6

High-throughput

0.611

High

927909

PPME1
Protein phosphatase methylesterase 1

2

2

Small-scale

0.611

High

227116

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

294675

RECQ4
ATP-dependent DNA helicase Q4

2

5

High-throughput

0.584

High

503858

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.584

High

616694

KS6B1
Ribosomal protein S6 kinase beta-1

2

5

Small-scale

0.584

High

927811

EIF3A
Eukaryotic translation initiation factor 3 subunit A

2

4

High-throughput

0.584

High

927874

SIK2
Serine/threonine-protein kinase SIK2

3

5

Small-scale

0.578

High

927804

FOXD4
Forkhead box protein D4

2

13

High-throughput

0.574

High

927839

TAFA3
Chemokine-like protein TAFA-3

2

1

High-throughput

0.574

High

374022

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

5

High-throughput

0.571

High

666060

SHC1
SHC-transforming protein 1

2

3

High-throughput

0.571

High

893882

CDC42
Cell division control protein 42 homolog

2

2

High-throughput

0.571

High

927805

GRB10
Growth factor receptor-bound protein 10

2

4

High-throughput

0.571

High

927826

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

Small-scale

0.563

High

542858

BRAF
Serine/threonine-protein kinase B-raf

1

5

Small-scale

0.561

High

927903

AMOL2
Angiomotin-like protein 2

1

3

Small-scale

0.561

High

244254

BRD4
Bromodomain-containing protein 4

2

0

High-throughput

0.559

High

862372

ACLY
ATP-citrate synthase

1

3

High-throughput

0.554

High

911332

RS11
Small ribosomal subunit protein uS17

1

2

High-throughput

0.554

High

927834

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

3

High-throughput

0.554

High

927844

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

High-throughput

0.554

High

850734

BMX
Cytoplasmic tyrosine-protein kinase BMX

2

0

High-throughput

0.547

High

927906

NOSIP
Nitric oxide synthase-interacting protein

1

0

Small-scale

0.537

High

213722

ENSA
Alpha-endosulfine

1

2

High-throughput

0.536

High

232835

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.536

High

364004

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.536

High

396715

S10A8
Protein S100-A8

1

7

High-throughput

0.536

High

416398

S10A9
Protein S100-A9

1

9

High-throughput

0.536

High

471573

TFPT
TCF3 fusion partner

1

1

High-throughput

0.536

High

678433

S10A7
Protein S100-A7

1

9

High-throughput

0.536

High

789251

CNDD3
Condensin-2 complex subunit D3

1

4

High-throughput

0.536

High

796540

KSYK
Tyrosine-protein kinase SYK

1

5

High-throughput

0.536

High

870636

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

890945

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

19

High-throughput

0.536

High

927797

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

7

High-throughput

0.536

High

927798

CDK16
Cyclin-dependent kinase 16

1

6

High-throughput

0.536

High

927810

SRTD2
SERTA domain-containing protein 2

1

7

High-throughput

0.536

High

927829

IER5
Immediate early response gene 5 protein

1

8

High-throughput

0.536

High

927873

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

1

High-throughput

0.536

High

927904

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

7

High-throughput

0.536

High

927907

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

2

High-throughput

0.536

High

804196

NOTC1
Neurogenic locus notch homolog protein 1

1

0

High-throughput

0.530

High

455307

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.515

High

927853

NDRG1
Protein NDRG1

1

3

Small-scale

0.515

High

394502

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

927816

NEDD8
NEDD8

1

1

High-throughput

0.515

High

134869

IMA3
Importin subunit alpha-3

1

0

High-throughput

0.513

High

208041

HAIR
Lysine-specific demethylase hairless

1

0

High-throughput

0.513

High

537621

NCF1
Neutrophil cytosol factor 1

1

0

High-throughput

0.513

High

911090

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

920748

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.513

High

927879

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

0

High-throughput

0.513

High

738524

TGFR1
TGF-beta receptor type-1

1

4

Small-scale

0.512

High

787452

MTOR
Serine/threonine-protein kinase mTOR

1

3

Small-scale

0.501

High

166551

DCLK1
Serine/threonine-protein kinase DCLK1

1

1

High-throughput

0.489

High

208907

FOXS1
Forkhead box protein S1

1

15

High-throughput

0.489

High

623614

IBP5
Insulin-like growth factor-binding protein 5

1

1

High-throughput

0.489

High

927799

CDK17
Cyclin-dependent kinase 17

1

6

High-throughput

0.489

High

927822

FX4L6
Forkhead box protein D4-like 6

1

15

High-throughput

0.489

High

927851

DUS19
Dual specificity protein phosphatase 19

1

2

High-throughput

0.489

High

927860

ZN414
Zinc finger protein 414

1

1

High-throughput

0.489

High

927870

RFIP5
Rab11 family-interacting protein 5

1

2

High-throughput

0.489

High

927894

SRTD1
SERTA domain-containing protein 1

1

1

High-throughput

0.489

High

927898

TRI35
E3 ubiquitin-protein ligase TRIM35

1

1

High-throughput

0.489

High

927901

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

6

High-throughput

0.489

High

927908

CCDC9
Coiled-coil domain-containing protein 9

1

1

High-throughput

0.489

High

927888

RRN3
RNA polymerase I-specific transcription initiation factor RRN3

1

0

Small-scale

0.480

High

316852

KLF8
Krueppel-like factor 8

1

0

High-throughput

0.479

High

125352

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

Small-scale

0.479

High

160495

AURKA
Aurora kinase A

1

3

High-throughput

0.479

High

162609

XPO1
Exportin-1

1

5

High-throughput

0.479

High

182128

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

3

High-throughput

0.479

High

205254

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

268010

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

322455

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

326573

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.479

High

345390

FOS
Protein c-Fos

1

6

High-throughput

0.479

High

369355

ESR1
Estrogen receptor

1

2

High-throughput

0.479

High

381917

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.479

High

485052

GLI2
Zinc finger protein GLI2

1

1

High-throughput

0.479

High

487314

ANDR
Androgen receptor

1

2

Small-scale

0.479

High

552462

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

573209

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.479

High

647870

MARK3
MAP/microtubule affinity-regulating kinase 3

1

5

Small-scale

0.479

High

673563

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.479

High

714509

GRK5
G protein-coupled receptor kinase 5

1

3

High-throughput

0.479

High

719332

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

2

High-throughput

0.479

High

770780

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.479

High

776289

MLH1
DNA mismatch repair protein Mlh1

1

2

High-throughput

0.479

High

779204

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

821159

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.479

High

826608

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.479

High

827906

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.479

High

832340

MCM2
DNA replication licensing factor MCM2

1

11

High-throughput

0.479

High

842819

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.479

High

843148

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.479

High

896020

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

897695

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

908325

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

927794

TBA4A
Tubulin alpha-4A chain

1

4

High-throughput

0.479

High

927795

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.479

High

927800

FABP5
Fatty acid-binding protein 5

1

1

High-throughput

0.479

High

927801

DSG1
Desmoglein-1

1

2

High-throughput

0.479

High

927802

ACK1
Activated CDC42 kinase 1

1

3

High-throughput

0.479

High

927812

RBM39
RNA-binding protein 39

1

5

High-throughput

0.479

High

927813

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

927814

TCAL1
Transcription elongation factor A protein-like 1

1

2

High-throughput

0.479

High

927815

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

1

Small-scale

0.479

High

927817

RBBP7
Histone-binding protein RBBP7

1

1

High-throughput

0.479

High

927818

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

927819

SMU1
WD40 repeat-containing protein SMU1

1

1

High-throughput

0.479

High

927823

CRY2
Cryptochrome-2

1

1

High-throughput

0.479

High

927825

DCA10
DDB1- and CUL4-associated factor 10

1

4

High-throughput

0.479

High

927832

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

927842

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

927843

AHI1
Jouberin

1

6

High-throughput

0.479

High

927845

FBXW8
F-box/WD repeat-containing protein 8

1

2

High-throughput

0.479

High

927847

ZBT38
Zinc finger and BTB domain-containing protein 38

1

1

Small-scale

0.479

High

927858

AURKB
Aurora kinase B

1

3

High-throughput

0.479

High

927859

FXL20
F-box/LRR-repeat protein 20

1

3

Small-scale

0.479

High

927862

RUFY1
RUN and FYVE domain-containing protein 1

1

2

High-throughput

0.479

High

927864

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.479

High

927875

KDM4C
Lysine-specific demethylase 4C

1

2

Small-scale

0.479

High

927880

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

1

High-throughput

0.479

High

927882

LATS2
Serine/threonine-protein kinase LATS2

1

3

High-throughput

0.479

High

927884

DCA13
DDB1- and CUL4-associated factor 13

1

2

High-throughput

0.479

High

927892

KS6B2
Ribosomal protein S6 kinase beta-2

1

5

High-throughput

0.479

High

927893

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

927895

DS13B
Dual specificity protein phosphatase 13B

1

4

High-throughput

0.479

High

927896

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.479

High

927900

FBW1A
F-box/WD repeat-containing protein 1A

1

1

High-throughput

0.479

High

927902

E41L3
Band 4.1-like protein 3

1

1

High-throughput

0.479

High

927913

DUS10
Dual specificity protein phosphatase 10

1

4

High-throughput

0.479

High

927889

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

1

High-throughput

0.470

High

927854

CBP
CREB-binding protein

1

0

Small-scale

0.460

High

150942

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

182683

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

255662

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

298398

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

386484

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

720198

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

828976

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

849987

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.458

High

921513

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

924451

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.458

High

927806

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

927807

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

0

Small-scale

0.458

High

927824

DCAF6
DDB1- and CUL4-associated factor 6

1

0

High-throughput

0.458

High

927833

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

927852

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

927855

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.458

High

927861

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

927863

NECD
Necdin

1

0

High-throughput

0.458

High

927865

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

927877

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

927881

ANLN
Anillin

1

0

High-throughput

0.458

High

927887

WSB2
WD repeat and SOCS box-containing protein 2

1

0

High-throughput

0.458

High

927897

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

111288

J3KPD3
RNA binding motif protein 7

1

8

High-throughput

0.445

High

170630

AXIN1
Axin-1

1

1

Small-scale

0.445

High

401807

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

496796

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

927827

CE170
Centrosomal protein of 170 kDa

1

1

High-throughput

0.445

High

927840

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

1

Small-scale

0.445

High

927841

KSR1
Kinase suppressor of Ras 1

1

7

Small-scale

0.445

High

927878

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.445

High

196295

PJA2
E3 ubiquitin-protein ligase Praja-2

1

1

Small-scale

0.437

High

338258

EGFR
Epidermal growth factor receptor

1

5

High-throughput

0.437

High

551661

DESP
Desmoplakin

1

5

High-throughput

0.437

High

600549

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.437

High

927808

PWP1
Periodic tryptophan protein 1 homolog

1

1

High-throughput

0.437

High

927821

ANR55
Ankyrin repeat domain-containing protein 55

1

2

High-throughput

0.437

High

927828

OTUD1
OTU domain-containing protein 1

1

1

High-throughput

0.437

High

927835

FBX42
F-box only protein 42

1

5

High-throughput

0.437

High

927836

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

927837

MOB3C
MOB kinase activator 3C

1

2

High-throughput

0.437

High

927876

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

927912

MAFB
Transcription factor MafB

1

3

High-throughput

0.437

High

275404

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

927886

SPHK1
Sphingosine kinase 1

1

0

Small-scale

0.426

High

927891

PI4KB
Phosphatidylinositol 4-kinase beta

1

0

Small-scale

0.426

High

927890

HACD3
Very-long-chain

2

0

High-throughput

0.305

High

927856

K1143
Uncharacterized protein KIAA1143

1

0

High-throughput

0.279

Low

329151

F107A
Actin-associated protein FAM107A

1

0

High-throughput

0.269

Low

927849

Q8NE08
COL25A1 protein

1

0

High-throughput

0.268

Low

242061

PAGE4
P antigen family member 4

1

0

High-throughput

0.249

Low

384624

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

927796

ZXDA
Zinc finger X-linked protein ZXDA

1

0

Small-scale

0.249

Low

927820

ZN750
Zinc finger protein 750

1

0

Small-scale

0.249

Low

927830

TENS2
Tensin-2

1

0

High-throughput

0.249

Low

927838

DET1
DET1 homolog

1

0

High-throughput

0.249

Low

927848

CA131
Uncharacterized protein C1orf131

1

0

High-throughput

0.249

Low

927869

DERL1
Derlin-1

1

0

Small-scale

0.249

Low

927885

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

927905

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

230607

KATIP
Katanin-interacting protein

1

0

High-throughput

0.232

Low

927872

TX101
Testis-expressed protein 101

1

0

High-throughput

0.232

Low

927911

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024