Protein: RB6I2
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)

Gene: RB6I2, ERC1
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q8IUD2

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0006355 - regulation of DNA-templated transcription
GO:0007252 - I-kappaB phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

904817

1433G
14-3-3 protein gamma

6

20

High-throughput

0.732

High

683520

1433B
14-3-3 protein beta/alpha

4

20

High-throughput

0.691

High

592678

RAB6A
Ras-related protein Rab-6A

1

13

Small-scale

0.680

High

647078

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

982241

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

1216163

RAB6B
Ras-related protein Rab-6B

1

16

Small-scale

0.647

High

678566

MK04
Mitogen-activated protein kinase 4

2

14

High-throughput

0.628

High

1077014

MARE1
Microtubule-associated protein RP/EB family member 1

2

3

High-throughput

0.628

High

1216119

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

18

High-throughput

0.618

High

1216132

KBTB7
Kelch repeat and BTB domain-containing protein 7

3

4

High-throughput

0.616

High

1043928

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

20

High-throughput

0.614

High

151074

DVL2
Segment polarity protein dishevelled homolog DVL-2

2

16

High-throughput

0.611

High

158505

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

2

20

Small-scale

0.611

High

1145820

CP135
Centrosomal protein of 135 kDa

2

17

High-throughput

0.611

High

1216175

NEMO
NF-kappa-B essential modulator

2

18

Small-scale

0.611

High

351671

TSHB
Thyrotropin subunit beta

2

0

High-throughput

0.602

High

272629

OFD1
Centriole and centriolar satellite protein OFD1

2

19

High-throughput

0.584

High

1068787

PCM1
Pericentriolar material 1 protein

2

2

High-throughput

0.584

High

1216122

NIN
Ninein

2

17

High-throughput

0.584

High

1216159

ANLN
Anillin

2

9

High-throughput

0.584

High

1216149

CDK19
Cyclin-dependent kinase 19

2

19

High-throughput

0.574

High

659300

DUS1
Dual specificity protein phosphatase 1

2

8

High-throughput

0.571

High

153144

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

20

High-throughput

0.536

High

167579

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

20

Small-scale

0.536

High

262286

ULK1
Serine/threonine-protein kinase ULK1

1

13

High-throughput

0.536

High

272883

KS6A4
Ribosomal protein S6 kinase alpha-4

1

12

High-throughput

0.536

High

318663

EYA4
Eyes absent homolog 4

1

5

High-throughput

0.536

High

347243

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.536

High

497266

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.536

High

740200

NUP62
Nuclear pore glycoprotein p62

1

10

High-throughput

0.536

High

813594

CAPZB
F-actin-capping protein subunit beta

1

7

High-throughput

0.536

High

841259

CDK7
Cyclin-dependent kinase 7

1

17

High-throughput

0.536

High

909777

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.536

High

969830

KIF23
Kinesin-like protein KIF23

1

15

High-throughput

0.536

High

972462

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

5

High-throughput

0.536

High

1023078

STK4
Serine/threonine-protein kinase 4

1

20

High-throughput

0.536

High

1041971

CUL3
Cullin-3

1

12

High-throughput

0.536

High

1146586

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.536

High

1216120

CDK20
Cyclin-dependent kinase 20

1

17

High-throughput

0.536

High

1216123

CE112
Centrosomal protein of 112 kDa

1

19

High-throughput

0.536

High

1216129

MK15
Mitogen-activated protein kinase 15

1

13

High-throughput

0.536

High

232296

KDM1A
Lysine-specific histone demethylase 1A

2

7

High-throughput

0.533

High

1152307

TWF2
Twinfilin-2

1

11

High-throughput

0.515

High

364957

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

1185573

CHSTF
Carbohydrate sulfotransferase 15

1

0

High-throughput

0.513

High

395104

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

942773

SRPK2
SRSF protein kinase 2

1

18

High-throughput

0.501

High

178907

MOT7
Monocarboxylate transporter 7

1

4

High-throughput

0.489

High

280893

KRT37
Keratin, type I cuticular Ha7

1

20

High-throughput

0.489

High

281012

KRT38
Keratin, type I cuticular Ha8

1

20

High-throughput

0.489

High

569100

DESM
Desmin

1

20

High-throughput

0.489

High

850751

BMX
Cytoplasmic tyrosine-protein kinase BMX

1

11

High-throughput

0.489

High

951873

SERF2
Small EDRK-rich factor 2

1

1

High-throughput

0.489

High

1105465

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

7

High-throughput

0.489

High

1216139

SGK3
Serine/threonine-protein kinase Sgk3

1

14

High-throughput

0.489

High

1216140

ULK4
Serine/threonine-protein kinase ULK4

1

14

High-throughput

0.489

High

1216152

RGAP1
Rac GTPase-activating protein 1

1

8

High-throughput

0.489

High

1216170

ING1
Inhibitor of growth protein 1

1

10

High-throughput

0.489

High

1216165

ITSN2
Intersectin-2

1

10

High-throughput

0.481

High

149018

CTRO
Citron Rho-interacting kinase

1

19

High-throughput

0.479

High

155026

NDC80
Kinetochore protein NDC80 homolog

1

16

High-throughput

0.479

High

201362

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

Small-scale

0.479

High

227963

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

302556

CE152
Centrosomal protein of 152 kDa

1

17

High-throughput

0.479

High

322842

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

408855

K1C18
Keratin, type I cytoskeletal 18

1

10

High-throughput

0.479

High

409148

K2C8
Keratin, type II cytoskeletal 8

1

4

High-throughput

0.479

High

422416

NFM
Neurofilament medium polypeptide

1

20

High-throughput

0.479

High

430251

PROF1
Profilin-1

1

2

High-throughput

0.479

High

438329

HS90B
Heat shock protein HSP 90-beta

1

10

High-throughput

0.479

High

518701

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

5

High-throughput

0.479

High

522044

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

639772

IKBA
NF-kappa-B inhibitor alpha

1

6

Small-scale

0.479

High

718972

PHB1
Prohibitin 1

1

10

High-throughput

0.479

High

736567

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.479

High

749653

BRCA1
Breast cancer type 1 susceptibility protein

1

12

High-throughput

0.479

High

802454

ATRX
Transcriptional regulator ATRX

1

12

Small-scale

0.479

High

808748

YAP1
Transcriptional coactivator YAP1

1

18

High-throughput

0.479

High

835437

GSK3A
Glycogen synthase kinase-3 alpha

1

18

High-throughput

0.479

High

835865

GSK3B
Glycogen synthase kinase-3 beta

1

20

High-throughput

0.479

High

872184

RD23A
UV excision repair protein RAD23 homolog A

1

4

Small-scale

0.479

High

896775

ARP3
Actin-related protein 3

1

20

High-throughput

0.479

High

927265

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

951634

RL19
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

957730

XIAP
E3 ubiquitin-protein ligase XIAP

1

6

Small-scale

0.479

High

961186

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

967264

EWS
RNA-binding protein EWS

1

6

High-throughput

0.479

High

1033289

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

10

High-throughput

0.479

High

1038508

HDAC1
Histone deacetylase 1

1

18

High-throughput

0.479

High

1039248

DCTN2
Dynactin subunit 2

1

2

High-throughput

0.479

High

1066351

KIF14
Kinesin-like protein KIF14

1

12

High-throughput

0.479

High

1078581

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.479

High

1118981

AMOT
Angiomotin

1

19

High-throughput

0.479

High

1135939

CE162
Centrosomal protein of 162 kDa

1

18

High-throughput

0.479

High

1164947

SAS6
Spindle assembly abnormal protein 6 homolog

1

17

High-throughput

0.479

High

1168567

SYNE3
Nesprin-3

1

17

High-throughput

0.479

High

1170677

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

1172664

CE128
Centrosomal protein of 128 kDa

1

19

High-throughput

0.479

High

1192476

CNTRL
Centriolin

1

17

High-throughput

0.479

High

1216128

LNX1
E3 ubiquitin-protein ligase LNX

1

17

Small-scale

0.479

High

1216130

BICD2
Protein bicaudal D homolog 2

1

18

High-throughput

0.479

High

1216131

FBF1
Fas-binding factor 1

1

16

High-throughput

0.479

High

1216133

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1216134

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

13

High-throughput

0.479

High

1216135

GOGA1
Golgin subfamily A member 1

1

15

High-throughput

0.479

High

1216137

SH3K1
SH3 domain-containing kinase-binding protein 1

1

12

High-throughput

0.479

High

1216141

BICD1
Protein bicaudal D homolog 1

1

15

High-throughput

0.479

High

1216143

SCLT1
Sodium channel and clathrin linker 1

1

20

High-throughput

0.479

High

1216144

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1216145

CEP89
Centrosomal protein of 89 kDa

1

18

High-throughput

0.479

High

1216148

PCGF1
Polycomb group RING finger protein 1

1

10

High-throughput

0.479

High

1216151

WWTR1
WW domain-containing transcription regulator protein 1

1

16

High-throughput

0.479

High

1216154

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1216155

NANOG
Homeobox protein NANOG

1

4

High-throughput

0.479

High

1216156

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

5

High-throughput

0.479

High

1216158

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

7

Small-scale

0.479

High

1216167

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1216172

MYO6
Unconventional myosin-VI

1

18

High-throughput

0.479

High

1216174

NINL
Ninein-like protein

1

18

High-throughput

0.479

High

682193

AKT2
RAC-beta serine/threonine-protein kinase

1

14

High-throughput

0.470

High

230977

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.458

High

514702

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

967912

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1216126

FLCN
Folliculin

1

0

Small-scale

0.458

High

476015

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.457

High

1216153

DNJC5
DnaJ homolog subfamily C member 5

1

4

High-throughput

0.457

High

1216168

PARP2
Poly [ADP-ribose] polymerase 2

1

3

Small-scale

0.457

High

1216161

DISC1
Disrupted in schizophrenia 1 protein

1

4

High-throughput

0.457

High

56660

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

4

High-throughput

0.445

High

968179

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

3

High-throughput

0.445

High

1124548

ODFP2
Outer dense fiber protein 2

1

18

High-throughput

0.445

High

1197871

SDCG8
Serologically defined colon cancer antigen 8

1

19

Small-scale

0.445

High

1199973

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

18

High-throughput

0.445

High

1216121

RYBP
RING1 and YY1-binding protein

1

4

High-throughput

0.445

High

116595

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

3

High-throughput

0.437

High

262025

PEX14
Peroxisomal membrane protein PEX14

1

2

High-throughput

0.437

High

329824

AGR2
Anterior gradient protein 2 homolog

1

6

High-throughput

0.437

High

444414

K1C19
Keratin, type I cytoskeletal 19

1

8

High-throughput

0.437

High

608034

FGFR4
Fibroblast growth factor receptor 4

1

7

High-throughput

0.437

High

611464

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

High-throughput

0.437

High

657518

TMOD1
Tropomodulin-1

1

7

High-throughput

0.437

High

823436

PAXI
Paxillin

1

15

High-throughput

0.437

High

1023500

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

2

High-throughput

0.437

High

1064461

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

7

High-throughput

0.437

High

1067444

EEA1
Early endosome antigen 1

1

17

High-throughput

0.437

High

1081091

CCDC6
Coiled-coil domain-containing protein 6

1

19

High-throughput

0.437

High

1119443

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

12

High-throughput

0.437

High

1159386

FBX42
F-box only protein 42

1

14

High-throughput

0.437

High

1165732

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1200471

NAA40
N-alpha-acetyltransferase 40

1

5

High-throughput

0.437

High

1216136

VP33A
Vacuolar protein sorting-associated protein 33A

1

4

High-throughput

0.437

High

1216138

PF21A
PHD finger protein 21A

1

17

High-throughput

0.437

High

1216146

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

1216147

MACD1
ADP-ribose glycohydrolase MACROD1

1

4

Small-scale

0.437

High

1216157

MED4
Mediator of RNA polymerase II transcription subunit 4

1

2

High-throughput

0.437

High

1216162

LATS2
Serine/threonine-protein kinase LATS2

1

20

High-throughput

0.437

High

1216166

SEP10
Septin-10

1

3

High-throughput

0.437

High

1216169

ANC2
Anaphase-promoting complex subunit 2

1

13

High-throughput

0.437

High

1216171

RCOR1
REST corepressor 1

1

6

High-throughput

0.437

High

1216173

TRI33
E3 ubiquitin-protein ligase TRIM33

1

15

High-throughput

0.437

High

264350

GGYF1
GRB10-interacting GYF protein 1

1

10

High-throughput

0.407

High

1186070

MICA3
[F-actin]-monooxygenase MICAL3

1

20

Small-scale

0.407

High

1216150

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

7

High-throughput

0.407

High

1216160

TLR9
Toll-like receptor 9

1

0

High-throughput

0.365

High

1216164

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

3

0

High-throughput

0.347

High

1216124

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.328

High

875865

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.279

Low

1102595

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1168307

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.279

Low

1216127

RASF8
Ras association domain-containing protein 8

1

0

High-throughput

0.269

Low

1202672

T200A
Transmembrane protein 200A

1

0

High-throughput

0.249

Low

1216125

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

1216142

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024