Protein: HELZ2
3'-5' exoribonuclease HELZ2 (EC 3.1.13.1) (ATP-dependent RNA helicase PRIC285) (EC 3.6.4.13) (Helicase with zinc finger 2, transcriptional coactivator) (Helicase with zinc finger domain 2) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein)

Gene: HELZ2
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9BYK8

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

995436

LG3BP
Galectin-3-binding protein

2

4

High-throughput

0.628

High

1149624

Z324B
Zinc finger protein 324B

2

0

High-throughput

0.602

High

1152528

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

2

11

High-throughput

0.584

High

1317071

CCG5
Voltage-dependent calcium channel gamma-5 subunit

2

1

High-throughput

0.574

High

370368

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

718166

BMI1
Polycomb complex protein BMI-1

2

8

High-throughput

0.571

High

489255

H14
Histone H1.4

1

7

High-throughput

0.536

High

616502

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.536

High

781444

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.536

High

807514

RS10
Small ribosomal subunit protein eS10

1

6

High-throughput

0.536

High

908132

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

945344

PRR3
Proline-rich protein 3

1

2

High-throughput

0.536

High

1052143

MAP7
Ensconsin

1

9

High-throughput

0.536

High

1073850

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

20

High-throughput

0.536

High

1076102

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.536

High

1288623

PABP5
Polyadenylate-binding protein 5

1

10

High-throughput

0.536

High

1308759

RBM4B
RNA-binding protein 4B

1

16

High-throughput

0.536

High

1317072

PURG
Purine-rich element-binding protein gamma

1

3

High-throughput

0.536

High

1317073

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

1061235

NUMA1
Nuclear mitotic apparatus protein 1

1

4

High-throughput

0.515

High

365051

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

1293109

ZN764
Zinc finger protein 764

1

0

High-throughput

0.513

High

1317074

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

0

High-throughput

0.513

High

992447

PPARA
Peroxisome proliferator-activated receptor alpha

1

12

Small-scale

0.501

High

225041

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.489

High

470542

H2A1
Histone H2A type 1

1

6

High-throughput

0.489

High

796171

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.489

High

347821

MYC
Myc proto-oncogene protein

1

11

Small-scale

0.479

High

374829

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

398084

ISG15
Ubiquitin-like protein ISG15

1

4

High-throughput

0.479

High

818435

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.479

High

1030469

G3BP1
Ras GTPase-activating protein-binding protein 1

1

11

High-throughput

0.479

High

1066637

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1080303

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.479

High

1085930

IF16
Gamma-interferon-inducible protein 16

1

10

High-throughput

0.479

High

1146811

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.479

High

1192203

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

Small-scale

0.479

High

1193173

SLN11
Schlafen family member 11

1

3

High-throughput

0.479

High

1237466

CGAS
Cyclic GMP-AMP synthase

1

2

High-throughput

0.479

High

1260898

DCAF4
DDB1- and CUL4-associated factor 4

1

3

High-throughput

0.479

High

1269540

ESR2
Estrogen receptor beta

1

11

High-throughput

0.479

High

1270422

HDAC2
Histone deacetylase 2

1

4

High-throughput

0.479

High

1317069

ANLN
Anillin

1

2

High-throughput

0.479

High

1317070

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

450941

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

1284384

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

56729

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

70196

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

11

High-throughput

0.445

High

1284315

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

11

High-throughput

0.445

High

967075

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.426

High

1082152

CRY1
Cryptochrome-1

1

0

Small-scale

0.426

High

179256

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024