Protein: DSX
Protein doublesex

Gene: DSX
Organism: Drosophila melanogaster
Interactions: 91
UniProt ID: P23023

Gene Ontology (top 5):
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

654012

DSX
Protein doublesex

3

3

Small-scale

0.845

High

197560

PAX6
Paired box protein Pax-6

2

7

High-throughput

0.594

High

638279

SINA
E3 ubiquitin-protein ligase sina

2

1

High-throughput

0.594

High

654053

Q95SJ2
GEO04222p1

3

1

High-throughput

0.590

High

478929

ABDB
Homeobox protein abdominal-B

2

3

Small-scale

0.586

High

654028

MED29
Mediator of RNA polymerase II transcription subunit 29

2

0

Small-scale

0.575

High

654059

ZN330
Zinc finger protein 330 homolog

2

0

High-throughput

0.569

High

654079

Q9VZF2
LD05244p

2

0

High-throughput

0.569

High

654082

Q9W219
GEO12575p1

2

0

High-throughput

0.569

High

654036

Q8IRY8
GEO12726p1

2

1

High-throughput

0.542

High

654055

Q9I7Z9
RH59219p

2

1

High-throughput

0.542

High

95202

E1JIH4
Uncharacterized protein, isoform D

1

1

High-throughput

0.541

High

654015

E78C
Ecdysone-induced protein 78C

1

6

High-throughput

0.541

High

654024

HR78
Nuclear hormone receptor HR78

1

11

High-throughput

0.541

High

654051

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

4

High-throughput

0.541

High

654054

FOXO
Forkhead box protein O

1

8

High-throughput

0.541

High

654074

Q9VTE8
GEO08928p1

1

1

High-throughput

0.541

High

654086

X2JDF3
Uncharacterized protein, isoform C

2

2

High-throughput

0.533

High

654060

Q9VDQ5
RE74560p

1

0

High-throughput

0.518

High

654081

Q9W1H0
HL01030p

1

0

High-throughput

0.518

High

117937

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

6

High-throughput

0.508

High

583356

DORS
Embryonic polarity protein dorsal

1

4

High-throughput

0.508

High

654025

Q4QQ70
IP09819p

1

1

High-throughput

0.508

High

654029

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.486

High

654032

Q8INT9
Uncharacterized protein, isoform A

1

0

High-throughput

0.486

High

654044

Q8T092
LD21421p

1

0

High-throughput

0.486

High

654077

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.486

High

654080

TAMO
Protein tamozhennic

1

0

High-throughput

0.486

High

235192

HTH
Homeobox protein homothorax

1

3

Small-scale

0.481

High

654013

EXD
Homeobox protein extradenticle

1

3

Small-scale

0.481

High

654030

Q7KUK4
Uncharacterized protein, isoform B

1

2

High-throughput

0.481

High

654058

Q9V9Q2
IP01335p

1

2

High-throughput

0.481

High

654067

Q9VM37
FI17813p1

1

1

High-throughput

0.481

High

654087

X2JDM5
Max-binding protein MNT

1

1

High-throughput

0.481

High

654014

CDC42
Cdc42 homolog

1

1

High-throughput

0.479

High

654017

TSG
Protein twisted gastrulation

1

1

High-throughput

0.464

High

654052

Q95RQ1
LD16414p

1

2

High-throughput

0.464

High

654071

Q9VSK1
GH09510p

1

1

High-throughput

0.464

High

654076

Q9VW92
LP20964p

1

2

High-throughput

0.464

High

654083

Q9W2C5
DUF753 domain-containing protein

1

1

High-throughput

0.464

High

654084

Q9W494
Crossveinless

1

1

High-throughput

0.464

High

654056

Q9N6D8
GH11591p

1

0

High-throughput

0.458

High

119491

M9NGP0
Max-binding protein MNT

1

1

High-throughput

0.457

High

654039

Q8MRU2
SD24632p

1

1

High-throughput

0.457

High

654042

Q8SXJ5
RE19601p

1

2

High-throughput

0.457

High

654045

Q8T0A1
LD17773p

1

3

High-throughput

0.457

High

654070

Q9VM83
CG17376 protein

1

2

High-throughput

0.451

High

654073

Q9VT88
Phospholipid scramblase

1

2

High-throughput

0.451

High

84902

B7Z0N0
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

119710

M9PBB4
Nimrod C1, isoform B

1

2

High-throughput

0.439

High

654033

Q8IQD8
Phospholipid scramblase

1

2

High-throughput

0.439

High

654038

Q8MR04
LP02978p

1

2

High-throughput

0.439

High

654075

Q9VU12
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

654027

Q7K2L7
GH27120p

1

1

High-throughput

0.437

High

654034

Q8IQI1
Uncharacterized protein, isoform A

1

1

High-throughput

0.417

High

654035

Q8IQV7
LP24295p

1

2

High-throughput

0.417

High

654049

Q8T479
AT12489p

1

1

High-throughput

0.417

High

654065

Q9VJU5
Nimrod C1, isoform A

1

2

High-throughput

0.417

High

654068

Q9VM81
Uncharacterized protein, isoform D

1

3

High-throughput

0.417

High

654021

MS84D
Male-specific sperm protein Mst84Dd

3

0

High-throughput

0.340

High

654047

Q8T3W6
AT27166p

3

0

High-throughput

0.340

High

654048

Q8T403
AT23551p

3

0

High-throughput

0.340

High

98515

F0JAR8
MIP29201p

2

0

High-throughput

0.310

High

467050

MS87F
Male-specific sperm protein Mst87F

2

0

High-throughput

0.310

High

654019

MS84B
Male-specific sperm protein Mst84Db

2

0

High-throughput

0.310

High

654023

Q058Z8
GEO11848p1

2

0

High-throughput

0.310

High

654026

Q6IG37
HDC07368

2

0

High-throughput

0.310

High

654040

Q8MZA7
AT17606p

2

0

High-throughput

0.310

High

654043

Q8SYC1
GEO08067p1

2

0

High-throughput

0.310

High

521146

UZIP
Protein unzipped

1

0

High-throughput

0.265

Low

535772

LAMB1
Laminin subunit beta-1

1

0

High-throughput

0.265

Low

654016

RS15A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.265

Low

654018

MS84A
Male-specific sperm protein Mst84Da

1

0

High-throughput

0.265

Low

654020

MS84C
Male-specific sperm protein Mst84Dc

1

0

High-throughput

0.265

Low

654022

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.265

Low

654031

PPN
Papilin

1

0

High-throughput

0.265

Low

654041

Q8SXG2
CG32711-PA long isoform

1

0

High-throughput

0.265

Low

654046

Q8T0I9
GH27479p

1

0

High-throughput

0.265

Low

654057

Q9V4B8
RE68558p

1

0

High-throughput

0.265

Low

654061

Q9VE75
V-type proton ATPase subunit a

1

0

High-throughput

0.265

Low

654062

SLEL
Slender lobes-like protein

1

0

High-throughput

0.265

Low

654063

Q9VJ24
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

654064

Q9VJM1
GEO13348p1

1

0

High-throughput

0.265

Low

654066

Q9VLL5
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.265

Low

654072

Q9VSQ3
GEO07612p1

1

0

High-throughput

0.265

Low

654078

Q9VZ44
Delta-like protein

1

0

High-throughput

0.265

Low

654085

XPO2
Exportin-2

1

0

High-throughput

0.265

Low

654037

Q8MLU9
DUF753 domain-containing protein

1

0

High-throughput

0.251

Low

654050

Q8WTI8
PFTAIRE-interacting factor 1A

1

0

High-throughput

0.238

Low

654069

Q9VM82
Uncharacterized protein, isoform A

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025