Protein: PCGF6
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)

Gene: PCGF6
Organism: Homo sapiens
Interactions: 169
UniProt ID: Q9BYE7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1304081

RING2
E3 ubiquitin-protein ligase RING2

11

20

Small-scale

0.981

High

988016

RING1
E3 ubiquitin-protein ligase RING1

8

19

Small-scale

0.973

High

1233190

RYBP
RING1 and YY1-binding protein

7

20

High-throughput

0.968

High

327861

CBX7
Chromobox protein homolog 7

6

20

Small-scale

0.956

High

1316705

CBX8
Chromobox protein homolog 8

5

20

High-throughput

0.939

High

1222219

YAF2
YY1-associated factor 2

5

20

High-throughput

0.927

High

123317

CBX4
E3 SUMO-protein ligase CBX4

4

20

High-throughput

0.909

High

1125901

BCORL
BCL-6 corepressor-like protein 1

3

20

High-throughput

0.861

High

718164

BMI1
Polycomb complex protein BMI-1

2

19

Small-scale

0.757

High

935201

H31
Histone H3.1

2

18

High-throughput

0.754

High

265707

E2F6
Transcription factor E2F6

7

20

Small-scale

0.746

High

898188

MAX
Protein max

7

16

Small-scale

0.746

High

1282142

LMBL2
Lethal(3)malignant brain tumor-like protein 2

6

20

Small-scale

0.740

High

903492

WDR5
WD repeat-containing protein 5

6

16

High-throughput

0.736

High

1027241

CBX3
Chromobox protein homolog 3

6

20

Small-scale

0.736

High

1218718

MGAP
MAX gene-associated protein

6

14

High-throughput

0.733

High

949876

CBX1
Chromobox protein homolog 1

5

20

High-throughput

0.722

High

1050537

TFDP1
Transcription factor Dp-1

5

5

High-throughput

0.722

High

1264229

AUTS2
Autism susceptibility gene 2 protein

4

20

Small-scale

0.704

High

586959

CSK22
Casein kinase II subunit alpha'

4

20

High-throughput

0.699

High

1038684

HDAC1
Histone deacetylase 1

4

10

High-throughput

0.699

High

1050567

TFDP2
Transcription factor Dp-2

4

5

High-throughput

0.699

High

347818

MYC
Myc proto-oncogene protein

4

20

Small-scale

0.692

High

934449

CSK21
Casein kinase II subunit alpha

3

20

High-throughput

0.675

High

1270421

HDAC2
Histone deacetylase 2

3

10

High-throughput

0.675

High

899023

PSME3
Proteasome activator complex subunit 3

3

2

High-throughput

0.667

High

1231968

MIER2
Mesoderm induction early response protein 2

3

6

High-throughput

0.667

High

1316707

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.663

High

316144

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.647

High

895898

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

1316695

PCGF6
Polycomb group RING finger protein 6

1

19

Small-scale

0.647

High

1316704

FBRS
Probable fibrosin-1

4

20

High-throughput

0.638

High

1152488

WBP2L
Postacrosomal sheath WW domain-binding protein

3

0

High-throughput

0.638

High

1257026

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

2

20

High-throughput

0.628

High

1273848

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

14

High-throughput

0.628

High

1316700

ZN644
Zinc finger protein 644

2

3

High-throughput

0.628

High

1138915

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.625

High

718424

PCGF2
Polycomb group RING finger protein 2

1

19

High-throughput

0.618

High

909077

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.618

High

952606

H33
Histone H3.3

1

18

High-throughput

0.618

High

1059190

CBX2
Chromobox protein homolog 2

1

20

High-throughput

0.618

High

1108538

PCGF3
Polycomb group RING finger protein 3

1

19

High-throughput

0.618

High

1167302

BCOR
BCL-6 corepressor

1

20

High-throughput

0.618

High

1197588

PCGF5
Polycomb group RING finger protein 5

1

19

High-throughput

0.618

High

1311534

PCGF1
Polycomb group RING finger protein 1

1

19

High-throughput

0.618

High

1316716

CARD8
Caspase recruitment domain-containing protein 8

2

0

High-throughput

0.602

High

1163303

CORO6
Coronin-6

2

14

High-throughput

0.574

High

795664

MAGA1
Melanoma-associated antigen 1

1

8

Small-scale

0.552

High

257520

CREST
Calcium-responsive transactivator

1

5

High-throughput

0.541

High

262565

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

396282

ARGI1
Arginase-1

1

3

High-throughput

0.536

High

617655

CRCM
Colorectal mutant cancer protein

1

2

High-throughput

0.536

High

800514

CBX5
Chromobox protein homolog 5

1

20

High-throughput

0.536

High

843030

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.536

High

843369

TCPD
T-complex protein 1 subunit delta

1

18

High-throughput

0.536

High

862633

FOSB
Protein FosB

1

14

High-throughput

0.536

High

903017

DCAF7
DDB1- and CUL4-associated factor 7

1

20

High-throughput

0.536

High

931839

CSK2B
Casein kinase II subunit beta

1

9

High-throughput

0.536

High

1029836

TIF1B
Transcription intermediary factor 1-beta

1

20

High-throughput

0.536

High

1080894

HSPB2
Heat shock protein beta-2

1

4

High-throughput

0.536

High

1283579

TRI52
E3 ubiquitin-protein ligase TRIM52

1

17

High-throughput

0.536

High

1086305

H31T
Histone H3.1t

1

18

High-throughput

0.527

High

1152383

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1184889

GDPD3
Lysophospholipase D GDPD3

1

0

High-throughput

0.513

High

1257186

ZN526
Zinc finger protein 526

1

0

High-throughput

0.513

High

175173

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

8

High-throughput

0.501

High

238614

PEX10
Peroxisome biogenesis factor 10

1

9

High-throughput

0.494

High

224652

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

2

High-throughput

0.489

High

365050

FRIL
Ferritin light chain

1

1

High-throughput

0.489

High

573462

TCPA
T-complex protein 1 subunit alpha

1

19

High-throughput

0.489

High

771026

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.489

High

821399

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.489

High

826868

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.489

High

943460

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.489

High

1231049

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

4

High-throughput

0.489

High

1306663

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.489

High

1308586

DHB14
17-beta-hydroxysteroid dehydrogenase 14

1

3

High-throughput

0.489

High

1316706

FBSL
Fibrosin-1-like protein

1

20

High-throughput

0.489

High

1316720

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

2

High-throughput

0.489

High

271183

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

20

High-throughput

0.481

High

1049140

TRI14
Tripartite motif-containing protein 14

1

17

High-throughput

0.481

High

1254607

MAGE2
Melanoma-associated antigen E2

1

8

Small-scale

0.481

High

1282030

TRI63
E3 ubiquitin-protein ligase TRIM63

1

19

High-throughput

0.481

High

1316696

TRI55
Tripartite motif-containing protein 55

1

19

High-throughput

0.481

High

1316712

MAGC2
Melanoma-associated antigen C2

1

8

Small-scale

0.481

High

1316715

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

15

High-throughput

0.481

High

121013

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

High-throughput

0.479

High

135283

E2F3
Transcription factor E2F3

1

15

High-throughput

0.479

High

197820

CRX
Cone-rod homeobox protein

1

18

High-throughput

0.479

High

268265

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

316982

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

325882

LATS1
Serine/threonine-protein kinase LATS1

1

7

High-throughput

0.479

High

414369

RB
Retinoblastoma-associated protein

1

2

High-throughput

0.479

High

432231

HS90A
Heat shock protein HSP 90-alpha

1

12

High-throughput

0.479

High

438494

HS90B
Heat shock protein HSP 90-beta

1

13

High-throughput

0.479

High

486828

MYB
Transcriptional activator Myb

1

4

High-throughput

0.479

High

505286

EGR2
E3 SUMO-protein ligase EGR2

1

6

High-throughput

0.479

High

563732

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

1

3

High-throughput

0.479

High

632884

TYY1
Transcriptional repressor protein YY1

1

15

High-throughput

0.479

High

636410

DNJB1
DnaJ homolog subfamily B member 1

1

3

High-throughput

0.479

High

641552

PAX6
Paired box protein Pax-6

1

16

High-throughput

0.479

High

692180

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

785403

ELK3
ETS domain-containing protein Elk-3

1

19

High-throughput

0.479

High

841315

CDK7
Cyclin-dependent kinase 7

1

7

High-throughput

0.479

High

884234

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

917875

H4
Histone H4

1

5

High-throughput

0.479

High

929051

SKP1
S-phase kinase-associated protein 1

1

11

High-throughput

0.479

High

943088

PHC1
Polyhomeotic-like protein 1

1

20

High-throughput

0.479

High

963679

E2F1
Transcription factor E2F1

1

15

High-throughput

0.479

High

971812

HEN1
Helix-loop-helix protein 1

1

2

High-throughput

0.479

High

983443

MAD1
Max dimerization protein 1

1

17

Small-scale

0.479

High

1024512

CAF1A
Chromatin assembly factor 1 subunit A

1

8

High-throughput

0.479

High

1024588

CAF1B
Chromatin assembly factor 1 subunit B

1

11

High-throughput

0.479

High

1051778

E2F2
Transcription factor E2F2

1

15

High-throughput

0.479

High

1059848

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

9

High-throughput

0.479

High

1071528

E2F5
Transcription factor E2F5

1

15

High-throughput

0.479

High

1081395

E2F4
Transcription factor E2F4

1

15

High-throughput

0.479

High

1085928

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1133114

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.479

High

1188819

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1189288

POGZ
Pogo transposable element with ZNF domain

1

3

High-throughput

0.479

High

1198058

KAISO
Transcriptional regulator Kaiso

1

4

High-throughput

0.479

High

1220886

PHC2
Polyhomeotic-like protein 2

1

20

High-throughput

0.479

High

1237581

DDX51
ATP-dependent RNA helicase DDX51

1

11

High-throughput

0.479

High

1242734

PHC3
Polyhomeotic-like protein 3

1

20

High-throughput

0.479

High

1245594

KDM2B
Lysine-specific demethylase 2B

1

20

High-throughput

0.479

High

1270908

KAT6A
Histone acetyltransferase KAT6A

1

18

High-throughput

0.479

High

1291111

CDCA5
Sororin

1

2

High-throughput

0.479

High

1295397

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

14

High-throughput

0.479

High

1300927

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1304889

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1315340

KLF16
Krueppel-like factor 16

1

16

High-throughput

0.479

High

1316123

KDM5D
Lysine-specific demethylase 5D

1

14

Small-scale

0.479

High

1316698

ADNP
Activity-dependent neuroprotector homeobox protein

1

2

High-throughput

0.479

High

1316701

WDR76
WD repeat-containing protein 76

1

20

High-throughput

0.479

High

1316703

ELP3
Elongator complex protein 3

1

1

High-throughput

0.479

High

1316708

DJC17
DnaJ homolog subfamily C member 17

1

6

High-throughput

0.479

High

1316709

CDK12
Cyclin-dependent kinase 12

1

12

High-throughput

0.479

High

1316711

RERE
Arginine-glutamic acid dipeptide repeats protein

1

7

High-throughput

0.479

High

1316713

LHX3
LIM/homeobox protein Lhx3

1

8

High-throughput

0.479

High

1316714

ZMYM2
Zinc finger MYM-type protein 2

1

2

High-throughput

0.479

High

1316719

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

1242291

PNMA1
Paraneoplastic antigen Ma1

1

3

High-throughput

0.464

High

942070

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.458

High

1158394

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.458

High

1188188

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.458

High

1267859

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

1294754

NSL1
Kinetochore-associated protein NSL1 homolog

1

0

High-throughput

0.458

High

1316697

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.458

High

1316699

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.458

High

1316702

KANL2
KAT8 regulatory NSL complex subunit 2

1

0

High-throughput

0.458

High

1316710

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.458

High

1316717

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

323091

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

15

High-throughput

0.437

High

953118

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.437

High

1128078

CEP78
Centrosomal protein of 78 kDa

1

7

High-throughput

0.437

High

1163839

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.437

High

1173999

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

18

Small-scale

0.437

High

1188002

EFL1
Elongation factor-like GTPase 1

1

6

High-throughput

0.437

High

1206042

MIB1
E3 ubiquitin-protein ligase MIB1

1

1

High-throughput

0.437

High

1316718

C170B
Centrosomal protein of 170 kDa protein B

1

16

High-throughput

0.437

High

894389

CDC42
Cell division control protein 42 homolog

1

1

Small-scale

0.417

High

217943

PRKY
Putative serine/threonine-protein kinase PRKY

1

6

High-throughput

0.407

High

952979

PR20E
Proline-rich protein 20E

1

1

High-throughput

0.407

High

1297318

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.279

Low

834450

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.251

Low

1158702

MSD2
Myb/SANT-like DNA-binding domain-containing protein 2

1

0

High-throughput

0.249

Low

56728

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024