Protein: CD80
T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)

Gene: CD80
Organism: Homo sapiens
Interactions: 77
UniProt ID: P33681

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0002710 - negative regulation of T cell mediated immunity
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0007166 - cell surface receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

706934

PD1L1
Programmed cell death 1 ligand 1

5

17

Small-scale

0.928

High

499345

CD28
T-cell-specific surface glycoprotein CD28

5

7

Small-scale

0.927

High

560040

CTLA4
Cytotoxic T-lymphocyte protein 4

4

7

Small-scale

0.906

High

436611

TNR16
Tumor necrosis factor receptor superfamily member 16

1

5

Small-scale

0.747

High

295796

ST17B
Serine/threonine-protein kinase 17B

1

7

High-throughput

0.691

High

397282

ADT2
ADP/ATP translocase 2

1

5

High-throughput

0.691

High

706897

PDCD1
Programmed cell death protein 1

1

3

Small-scale

0.647

High

60302

POTEF
POTE ankyrin domain family member F

1

5

High-throughput

0.618

High

163572

BTAF1
TATA-binding protein-associated factor 172

1

2

High-throughput

0.618

High

214751

PM34
Peroxisomal membrane protein PMP34

1

7

High-throughput

0.618

High

234100

FADS1
Acyl-CoA

1

2

High-throughput

0.618

High

706902

KMCP1
Kidney mitochondrial carrier protein 1

1

6

High-throughput

0.618

High

706905

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

6

High-throughput

0.618

High

706906

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

1

6

High-throughput

0.618

High

706912

SAMC
Mitochondrial S-adenosylmethionine carrier protein

1

7

High-throughput

0.618

High

706933

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

0

High-throughput

0.578

High

706884

CD80
T-lymphocyte activation antigen CD80

1

17

Small-scale

0.575

High

273553

UTP20
Small subunit processome component 20 homolog

1

1

High-throughput

0.536

High

598434

NF1
Neurofibromin

1

5

High-throughput

0.536

High

622767

COT2
COUP transcription factor 2

1

5

High-throughput

0.536

High

706885

MTOR
Serine/threonine-protein kinase mTOR

1

14

High-throughput

0.536

High

706887

KNTC1
Kinetochore-associated protein 1

1

1

High-throughput

0.536

High

706899

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

3

High-throughput

0.536

High

706919

EXOC6
Exocyst complex component 6

1

1

High-throughput

0.536

High

706936

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.536

High

706903

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

0

High-throughput

0.513

High

706917

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

1

0

High-throughput

0.513

High

706935

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.513

High

155541

TNPO2
Transportin-2

1

18

High-throughput

0.489

High

217233

ORC5
Origin recognition complex subunit 5

1

2

High-throughput

0.489

High

706888

TBA4A
Tubulin alpha-4A chain

1

5

High-throughput

0.489

High

706889

PRKDC
DNA-dependent protein kinase catalytic subunit

1

12

High-throughput

0.489

High

706890

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

706891

VAC14
Protein VAC14 homolog

1

14

High-throughput

0.489

High

706892

ATM
Serine-protein kinase ATM

1

13

High-throughput

0.489

High

706894

TBB3
Tubulin beta-3 chain

1

7

High-throughput

0.489

High

706895

ATR
Serine/threonine-protein kinase ATR

1

13

High-throughput

0.489

High

706896

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

4

High-throughput

0.489

High

706898

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.489

High

706900

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

4

High-throughput

0.489

High

706909

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

1

High-throughput

0.489

High

706910

BRAT1
BRCA1-associated ATM activator 1

1

1

High-throughput

0.489

High

706911

THADA
tRNA

1

3

High-throughput

0.489

High

706913

5MP2
eIF5-mimic protein 2

1

5

High-throughput

0.489

High

706916

INT1
Integrator complex subunit 1

1

1

High-throughput

0.489

High

706918

NAV1
Neuron navigator 1

1

3

High-throughput

0.489

High

706920

SFXN5
Sideroflexin-5

1

2

High-throughput

0.489

High

706921

FAKD4
FAST kinase domain-containing protein 4

1

4

High-throughput

0.489

High

706922

OTUL
Ubiquitin thioesterase otulin

1

4

High-throughput

0.489

High

706924

SFXN3
Sideroflexin-3

1

2

High-throughput

0.489

High

706925

INT2
Integrator complex subunit 2

1

2

High-throughput

0.489

High

706926

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

3

High-throughput

0.489

High

706932

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

6

High-throughput

0.489

High

706937

XPO7
Exportin-7

1

18

High-throughput

0.489

High

706938

BCS1
Mitochondrial chaperone BCS1

1

5

High-throughput

0.489

High

706940

TNPO3
Transportin-3

1

20

High-throughput

0.489

High

64420

RTL8C
Retrotransposon Gag-like protein 8C

1

0

High-throughput

0.279

Low

199281

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.279

Low

200373

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.279

Low

207020

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.279

Low

298204

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.279

Low

706886

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.279

Low

706893

MTX1
Metaxin-1

1

0

High-throughput

0.279

Low

706901

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.279

Low

706904

ATLA3
Atlastin-3

1

0

High-throughput

0.279

Low

706907

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.279

Low

706908

TTI2
TELO2-interacting protein 2

1

0

High-throughput

0.279

Low

706914

DPH6
Diphthine--ammonia ligase

1

0

High-throughput

0.279

Low

706915

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.279

Low

706923

F118B
Protein FAM118B

1

0

High-throughput

0.279

Low

706927

GLP3L
Golgi phosphoprotein 3-like

1

0

High-throughput

0.279

Low

706928

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

706929

NOL11
Nucleolar protein 11

1

0

High-throughput

0.279

Low

706930

NJMU
Protein Njmu-R1

1

0

High-throughput

0.279

Low

706931

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.279

Low

706939

AP3M1
AP-3 complex subunit mu-1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024