Protein: 1433E
14-3-3 protein epsilon (14-3-3E)

Gene: 1433E, Ywhae
Organism: Mus musculus
Interactions: 186
UniProt ID: P62259

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001764 - neuron migration
GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
GO:0005246 - calcium channel regulator activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

905329

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

2

17

High-throughput

0.757

High

99940

SYGP1
Ras/Rap GTPase-activating protein SynGAP

4

7

High-throughput

0.694

High

910331

1433B
14-3-3 protein beta/alpha

1

19

Small-scale

0.691

High

910342

NDEL1
Nuclear distribution protein nudE-like 1

3

4

Small-scale

0.660

High

910260

DLG4
Disks large homolog 4

3

3

High-throughput

0.650

High

910228

ARG28
Rho guanine nucleotide exchange factor 28

1

8

Small-scale

0.647

High

910299

HDAC7
Histone deacetylase 7

3

12

Small-scale

0.631

High

910281

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

2

3

Small-scale

0.619

High

655938

BRAF
Serine/threonine-protein kinase B-raf

1

15

High-throughput

0.618

High

910224

1433Z
14-3-3 protein zeta/delta

1

19

High-throughput

0.618

High

910226

1433F
14-3-3 protein eta

1

19

High-throughput

0.618

High

910254

KSR1
Kinase suppressor of Ras 1

1

10

High-throughput

0.618

High

910249

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

13

Small-scale

0.612

High

910247

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

4

High-throughput

0.611

High

910334

DLGP1
Disks large-associated protein 1

2

1

High-throughput

0.611

High

910353

HOME1
Homer protein homolog 1

2

5

High-throughput

0.611

High

677631

CTND1
Catenin delta-1

2

4

Small-scale

0.584

High

610571

CBL
E3 ubiquitin-protein ligase CBL

2

5

High-throughput

0.571

High

724581

IRS1
Insulin receptor substrate 1

2

9

Small-scale

0.571

High

910325

RIN1
Ras and Rab interactor 1

1

6

Small-scale

0.552

High

910265

TFDP2
Transcription factor Dp-2

1

1

Small-scale

0.539

High

910236

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

1

High-throughput

0.536

High

910263

CRK
Adapter molecule crk

1

4

High-throughput

0.536

High

910303

FTM
Protein fantom

1

5

High-throughput

0.536

High

910295

TBCD4
TBC1 domain family member 4

2

3

Small-scale

0.521

High

868860

ATX1
Ataxin-1

1

1

High-throughput

0.515

High

722728

RAB6A
Ras-related protein Rab-6A

1

1

High-throughput

0.481

High

910225

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.481

High

56841

TANC2
Protein TANC2

1

5

High-throughput

0.479

High

93264

E9PXB7
E3 ubiquitin-protein ligase

1

12

Small-scale

0.479

High

93299

E9PYF4
LIM domain only 7

1

5

High-throughput

0.479

High

139359

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

7

High-throughput

0.479

High

140059

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

11

High-throughput

0.479

High

250567

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.479

High

291666

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

2

High-throughput

0.479

High

292332

DCX
Neuronal migration protein doublecortin

1

4

High-throughput

0.479

High

292465

SYN1
Synapsin-1

1

7

High-throughput

0.479

High

292560

SPD2A
SH3 and PX domain-containing protein 2A

1

5

High-throughput

0.479

High

449418

NUCL
Nucleolin

1

4

High-throughput

0.479

High

486090

EF1A1
Elongation factor 1-alpha 1

1

5

High-throughput

0.479

High

497973

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.479

High

513666

HS90B
Heat shock protein HSP 90-beta

1

9

High-throughput

0.479

High

541445

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.479

High

541460

MAP1B
Microtubule-associated protein 1B

1

6

High-throughput

0.479

High

562127

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

8

High-throughput

0.479

High

702835

KIF5A
Kinesin heavy chain isoform 5A

1

7

High-throughput

0.479

High

804937

AINX
Alpha-internexin

1

4

High-throughput

0.479

High

808343

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

12

Small-scale

0.479

High

812918

CAZA1
F-actin-capping protein subunit alpha-1

1

2

High-throughput

0.479

High

812936

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.479

High

813897

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.479

High

822748

CBR1
Carbonyl reductase [NADPH] 1

1

2

High-throughput

0.479

High

823143

MPIP3
M-phase inducer phosphatase 3

1

9

Small-scale

0.479

High

851083

ADT2
ADP/ATP translocase 2

1

3

High-throughput

0.479

High

873099

DDX6
Probable ATP-dependent RNA helicase DDX6

1

9

High-throughput

0.479

High

880606

ATPB
ATP synthase subunit beta, mitochondrial

1

6

High-throughput

0.479

High

882680

FUS
RNA-binding protein FUS

1

3

High-throughput

0.479

High

906225

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

9

High-throughput

0.479

High

910219

EF1A2
Elongation factor 1-alpha 2

1

5

High-throughput

0.479

High

910220

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

910222

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.479

High

910223

CYH2
Cytohesin-2

1

4

High-throughput

0.479

High

910227

CASP3
Caspase-3

1

1

High-throughput

0.479

High

910229

MPRIP
Myosin phosphatase Rho-interacting protein

1

6

High-throughput

0.479

High

910231

MARK3
MAP/microtubule affinity-regulating kinase 3

1

20

High-throughput

0.479

High

910232

ATPA
ATP synthase subunit alpha, mitochondrial

1

8

High-throughput

0.479

High

910233

NF1
Neurofibromin

1

6

High-throughput

0.479

High

910234

MARK2
Serine/threonine-protein kinase MARK2

1

20

High-throughput

0.479

High

910235

DMWD
Dystrophia myotonica WD repeat-containing protein

1

6

High-throughput

0.479

High

910238

Q3U2G2
Heat shock 70 kDa protein 4

1

7

High-throughput

0.479

High

910242

SRBS2
Sorbin and SH3 domain-containing protein 2

1

9

High-throughput

0.479

High

910244

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

2

High-throughput

0.479

High

910245

PACS2
Phosphofurin acidic cluster sorting protein 2

1

1

High-throughput

0.479

High

910246

Q3ZB59
Growth factor receptor bound protein 2-associated protein 2

1

9

High-throughput

0.479

High

910248

BRSK1
Serine/threonine-protein kinase BRSK1

1

20

High-throughput

0.479

High

910250

GRDN
Girdin

1

7

High-throughput

0.479

High

910252

CAPR1
Caprin-1

1

4

High-throughput

0.479

High

910255

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

13

High-throughput

0.479

High

910257

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

910258

KINH
Kinesin-1 heavy chain

1

8

High-throughput

0.479

High

910259

CP131
Centrosomal protein of 131 kDa

1

5

High-throughput

0.479

High

910261

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.479

High

910262

DBNL
Drebrin-like protein

1

3

High-throughput

0.479

High

910264

TFE3
Transcription factor E3

1

7

High-throughput

0.479

High

910266

NUAK1
NUAK family SNF1-like kinase 1

1

20

High-throughput

0.479

High

910267

SYN2
Synapsin-2

1

5

High-throughput

0.479

High

910268

CRTC1
CREB-regulated transcription coactivator 1

1

8

High-throughput

0.479

High

910269

RAB3I
Rab-3A-interacting protein

1

1

High-throughput

0.479

High

910270

CLH1
Clathrin heavy chain 1

1

1

High-throughput

0.479

High

910271

GIT1
ARF GTPase-activating protein GIT1

1

8

High-throughput

0.479

High

910272

BRSK2
Serine/threonine-protein kinase BRSK2

1

20

High-throughput

0.479

High

910273

CE170
Centrosomal protein of 170 kDa

1

9

High-throughput

0.479

High

910274

DLGP3
Disks large-associated protein 3

1

1

High-throughput

0.479

High

910275

DCLK2
Serine/threonine-protein kinase DCLK2

1

11

High-throughput

0.479

High

910276

ERC2
ERC protein 2

1

6

High-throughput

0.479

High

910277

NEB2
Neurabin-2

1

7

High-throughput

0.479

High

910278

TAOK2
Serine/threonine-protein kinase TAO2

1

19

High-throughput

0.479

High

910279

R3HD2
R3H domain-containing protein 2

1

5

High-throughput

0.479

High

910280

RIMS3
Regulating synaptic membrane exocytosis protein 3

1

6

High-throughput

0.479

High

910282

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.479

High

910284

RHG33
Rho GTPase-activating protein 33

1

9

High-throughput

0.479

High

910285

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

10

High-throughput

0.479

High

910286

WDR48
WD repeat-containing protein 48

1

7

High-throughput

0.479

High

910287

FRM4A
FERM domain-containing protein 4A

1

9

High-throughput

0.479

High

910289

BAIP2
BAR/IMD domain-containing adapter protein 2

1

2

High-throughput

0.479

High

910290

SYLC
Leucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

910291

FLNA
Filamin-A

1

2

High-throughput

0.479

High

910292

APH1A
Gamma-secretase subunit APH-1A

1

1

Small-scale

0.479

High

910293

LRCH3
DISP complex protein LRCH3

1

11

High-throughput

0.479

High

910296

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.479

High

910297

DOCK8
Dedicator of cytokinesis protein 8

1

5

High-throughput

0.479

High

910300

APH1B
Gamma-secretase subunit APH-1B

1

1

Small-scale

0.479

High

910301

WDR37
WD repeat-containing protein 37

1

5

High-throughput

0.479

High

910304

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

5

High-throughput

0.479

High

910305

TRI32
E3 ubiquitin-protein ligase TRIM32

1

4

High-throughput

0.479

High

910306

NAV1
Neuron navigator 1

1

4

High-throughput

0.479

High

910307

FBX4
F-box only protein 4

1

1

Small-scale

0.479

High

910308

MARK4
MAP/microtubule affinity-regulating kinase 4

1

20

High-throughput

0.479

High

910309

SYN3
Synapsin-3

1

5

High-throughput

0.479

High

910311

PACS1
Phosphofurin acidic cluster sorting protein 1

1

1

High-throughput

0.479

High

910313

ATAT
Alpha-tubulin N-acetyltransferase 1

1

1

High-throughput

0.479

High

910314

CBR3
Carbonyl reductase [NADPH] 3

1

2

High-throughput

0.479

High

910315

AHI1
Jouberin

1

6

High-throughput

0.479

High

910318

MARK1
Serine/threonine-protein kinase MARK1

1

19

High-throughput

0.479

High

910319

SFPQ
Splicing factor, proline- and glutamine-rich

1

6

High-throughput

0.479

High

910320

ACLY
ATP-citrate synthase

1

3

High-throughput

0.479

High

910322

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

10

High-throughput

0.479

High

910323

FRM4B
FERM domain-containing protein 4B

1

10

High-throughput

0.479

High

910326

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

6

High-throughput

0.479

High

910327

HOME3
Homer protein homolog 3

1

6

High-throughput

0.479

High

910328

NONO
Non-POU domain-containing octamer-binding protein

1

5

High-throughput

0.479

High

910329

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

7

High-throughput

0.479

High

910330

GGYF1
GRB10-interacting GYF protein 1

1

2

High-throughput

0.479

High

910332

TBCD7
TBC1 domain family member 7

1

1

High-throughput

0.479

High

910335

EF1G
Elongation factor 1-gamma

1

5

High-throughput

0.479

High

910337

KLC4
Kinesin light chain 4

1

8

High-throughput

0.479

High

910338

TSC1
Hamartin

1

9

High-throughput

0.479

High

910339

WWTR1
WW domain-containing transcription regulator protein 1

1

14

Small-scale

0.479

High

910341

RIMS2
Regulating synaptic membrane exocytosis protein 2

1

10

High-throughput

0.479

High

910343

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

3

High-throughput

0.479

High

910344

LANC2
LanC-like protein 2

1

1

High-throughput

0.479

High

910345

DCLK1
Serine/threonine-protein kinase DCLK1

1

12

High-throughput

0.479

High

910346

GIT2
ARF GTPase-activating protein GIT2

1

9

High-throughput

0.479

High

910348

SRCN1
SRC kinase signaling inhibitor 1

1

1

High-throughput

0.479

High

910349

KI21B
Kinesin-like protein KIF21B

1

7

High-throughput

0.479

High

910350

DREB
Drebrin

1

5

High-throughput

0.479

High

910351

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

102922

G3X9H5
Huntingtin

1

0

High-throughput

0.458

High

192692

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.458

High

392764

PRIO
Major prion protein

1

0

Small-scale

0.458

High

788754

PURA
Transcriptional activator protein Pur-alpha

1

0

High-throughput

0.458

High

910221

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

910237

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

910294

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.458

High

910298

VP9D1
VPS9 domain-containing protein 1

1

0

High-throughput

0.458

High

910316

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.458

High

910317

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

1

0

High-throughput

0.458

High

910321

MSD4
Myb/SANT-like DNA-binding domain-containing protein 4

1

0

High-throughput

0.458

High

910347

ITA2B
Integrin alpha-IIb

1

1

High-throughput

0.457

High

910324

SH3B4
SH3 domain-binding protein 4

1

2

Small-scale

0.457

High

93548

DESP
Desmoplakin

1

5

High-throughput

0.445

High

139765

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.445

High

828445

CENPC
Centromere protein C

1

2

High-throughput

0.445

High

910251

LCP2
Lymphocyte cytosolic protein 2

1

5

High-throughput

0.445

High

910253

VDAC1
Voltage-dependent anion-selective channel protein 1

1

3

High-throughput

0.445

High

910288

COX15
Heme A synthase COX15

1

1

High-throughput

0.445

High

910302

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

12

Small-scale

0.445

High

910310

DNM1L
Dynamin-1-like protein

1

3

High-throughput

0.445

High

910333

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

5

High-throughput

0.445

High

910340

XPO7
Exportin-7

1

1

High-throughput

0.445

High

910352

HDAC5
Histone deacetylase 5

1

12

High-throughput

0.445

High

56981

A2A9M5
Dedicator of cytokinesis 7

1

5

High-throughput

0.437

High

103331

RFIP2
Rab11 family-interacting protein 2

1

9

High-throughput

0.437

High

897157

ACTZ
Alpha-centractin

1

5

High-throughput

0.437

High

910239

Q3UJF1
Histone deacetylase

1

12

High-throughput

0.437

High

910240

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

1

8

High-throughput

0.437

High

910243

K22O
Keratin, type II cytoskeletal 2 oral

1

2

High-throughput

0.437

High

910283

Q80VE5
TBC1 domain family, member 22B

1

5

High-throughput

0.437

High

910312

EDC3
Enhancer of mRNA-decapping protein 3

1

1

High-throughput

0.437

High

910336

BORC5
BLOC-1-related complex subunit 5

1

1

High-throughput

0.437

High

848597

CAV3
Caveolin-3

1

0

High-throughput

0.426

High

910230

THIOM
Thioredoxin, mitochondrial

1

0

High-throughput

0.426

High

57251

A2AKD7
Syntrophin, acidic 1

1

3

High-throughput

0.407

High

910256

SOAT1
Sterol O-acyltransferase 1

1

1

High-throughput

0.407

High

371705

CFAD
Complement factor D

1

0

High-throughput

0.249

Low

910241

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024