Protein: SPT5H
Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (dSpt5)

Gene: SPT5H, Spt5
Organism: Drosophila melanogaster
Interactions: 24
UniProt ID: Q9V460

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000993 - RNA polymerase II complex binding
GO:0003682 - chromatin binding
GO:0003729 - mRNA binding
GO:0005700 - polytene chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1457477

SPT4H
Transcription elongation factor SPT4

6

4

Small-scale

0.928

High

1342983

PHO
Polycomb protein PHO

2

4

Small-scale

0.620

High

756484

ECR
Ecdysone receptor

1

19

Small-scale

0.515

High

1440005

Q9I7J8
FI01424p

1

2

High-throughput

0.508

High

1458016

Q9U4G5
AXIN1 up-regulated 1, isoform A

1

0

High-throughput

0.486

High

633983

TRX
Histone-lysine N-methyltransferase trithorax

1

17

Small-scale

0.479

High

1465524

Q9VHM5
RT10616p

1

3

High-throughput

0.464

High

1465528

Q9VRV4
D19B

1

2

High-throughput

0.464

High

1465529

Q9VRV5
D19A

1

2

High-throughput

0.464

High

896143

MSL1
Protein male-specific lethal-1

1

0

Small-scale

0.458

High

1175065

NETB
Netrin-B

1

1

High-throughput

0.442

High

1343855

Q8SXN9
polynucleotide adenylyltransferase

1

1

High-throughput

0.439

High

1345580

Q8T3H9
AT04280p

1

1

High-throughput

0.439

High

120339

M9PD17
Gigas, isoform B

1

1

High-throughput

0.437

High

1047187

KELC
Ring canal kelch protein [Cleaved into: Kelch short protein]

1

1

Small-scale

0.437

High

1268920

RS19B
Small ribosomal subunit protein eS19B

1

1

High-throughput

0.437

High

1465527

Q9VR61
non-specific serine/threonine protein kinase

1

6

High-throughput

0.437

High

1465530

Q9W1M9
Exosome complex component RRP4

1

1

Small-scale

0.437

High

52773

A1Z743
polynucleotide adenylyltransferase

1

1

High-throughput

0.417

High

1465525

Q9VNC4
Uncharacterized protein, isoform B

1

5

High-throughput

0.417

High

756938

FAS2
Fasciclin-2

1

3

High-throughput

0.407

High

1465523

Q9VH81
protein-serine/threonine phosphatase

1

13

High-throughput

0.407

High

1465526

RAB26
Ras-related protein Rab-26

1

0

High-throughput

0.265

Low

119840

HAKAI
E3 ubiquitin-protein ligase Hakai

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025