Protein: SPAST
Spastin (EC 5.6.1.1)

Gene: SPAST
Organism: Mus musculus
Interactions: 81
UniProt ID: Q9QYY8

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000922 - spindle pole
GO:0001578 - microtubule bundle formation
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

872748

PRS6B
26S proteasome regulatory subunit 6B

1

11

High-throughput

0.618

High

924249

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

16

High-throughput

0.618

High

967700

TERA
Transitional endoplasmic reticulum ATPase

1

19

High-throughput

0.618

High

1193455

NAV3
Neuron navigator 3

1

8

High-throughput

0.618

High

1208058

ANK2
Ankyrin-2

1

1

High-throughput

0.618

High

1351632

SPAST
Spastin

1

17

High-throughput

0.618

High

56995

A2A9M5
Dedicator of cytokinesis 7

1

1

High-throughput

0.479

High

61660

KCNB2
Potassium voltage-gated channel subfamily B member 2

1

3

High-throughput

0.479

High

139047

BIN1
Myc box-dependent-interacting protein 1

1

4

High-throughput

0.479

High

192570

PURB
Transcriptional regulator protein Pur-beta

1

2

High-throughput

0.479

High

223087

STRN
Striatin

1

8

High-throughput

0.479

High

524516

RL7A
Large ribosomal subunit protein eL8

1

4

High-throughput

0.479

High

550507

H12
Histone H1.2

1

7

High-throughput

0.479

High

592777

MTAP2
Microtubule-associated protein 2

1

10

High-throughput

0.479

High

792288

TCPQ
T-complex protein 1 subunit theta

1

11

High-throughput

0.479

High

794638

H14
Histone H1.4

1

7

High-throughput

0.479

High

794667

H15
Histone H1.5

1

7

High-throughput

0.479

High

917021

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.479

High

956484

FHL1
Four and a half LIM domains protein 1

1

1

High-throughput

0.479

High

968758

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

3

High-throughput

0.479

High

1111725

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

1113403

Q3UZG4
Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

1

1

High-throughput

0.479

High

1122669

TR150
Thyroid hormone receptor-associated protein 3

1

4

High-throughput

0.479

High

1131960

NACAD
NAC-alpha domain-containing protein 1

1

3

High-throughput

0.479

High

1142937

KTN1
Kinectin

1

6

High-throughput

0.479

High

1143728

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

7

High-throughput

0.479

High

1143917

SH3G1
Endophilin-A2

1

5

High-throughput

0.479

High

1149134

CE170
Centrosomal protein of 170 kDa

1

5

High-throughput

0.479

High

1149162

LAR4B
La-related protein 4B

1

1

High-throughput

0.479

High

1161761

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

1

3

High-throughput

0.479

High

1193442

ASTRB
Protein Aster-B

1

1

High-throughput

0.479

High

1194336

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

4

High-throughput

0.479

High

1206522

ATLA1
Atlastin-1

1

4

High-throughput

0.479

High

1206537

Q8BH80
Vesicle-associated membrane protein, associated protein B and C

1

8

High-throughput

0.479

High

1207107

Q8BPK8
Agenet-like domain-containing protein

1

2

High-throughput

0.479

High

1207291

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

1208128

BCAS3
BCAS3 microtubule associated cell migration factor

1

3

High-throughput

0.479

High

1208430

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

4

High-throughput

0.479

High

1208634

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

6

High-throughput

0.479

High

1225167

HACD3
Very-long-chain

1

3

High-throughput

0.479

High

1246855

CDC16
Cell division cycle protein 16 homolog

1

7

High-throughput

0.479

High

1257485

VIGLN
Vigilin

1

4

High-throughput

0.479

High

1265091

SMAP1
Stromal membrane-associated protein 1

1

2

High-throughput

0.479

High

1265728

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

1265747

LRC59
Leucine-rich repeat-containing protein 59 [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]

1

4

High-throughput

0.479

High

1307930

RTN4
Reticulon-4

1

2

High-throughput

0.479

High

1307946

RRBP1
Ribosome-binding protein 1

1

6

High-throughput

0.479

High

1321859

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

5

High-throughput

0.479

High

1321951

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

1322110

HM13
Minor histocompatibility antigen H13

1

2

High-throughput

0.479

High

1337513

HIP1R
Huntingtin-interacting protein 1-related protein

1

5

High-throughput

0.479

High

1337537

AL9A1
4-trimethylaminobutyraldehyde dehydrogenase

1

2

High-throughput

0.479

High

1351625

MAGD1
Melanoma-associated antigen D1

1

3

High-throughput

0.479

High

1351629

MAP1A
Microtubule-associated protein 1A

1

5

High-throughput

0.479

High

1351631

PCLO
Protein piccolo

1

5

High-throughput

0.479

High

1351633

AFAD
Afadin

1

5

High-throughput

0.479

High

1351634

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

6

High-throughput

0.479

High

1351635

PDC6I
Programmed cell death 6-interacting protein

1

11

High-throughput

0.479

High

1351636

VAPA
Vesicle-associated membrane protein-associated protein A

1

8

High-throughput

0.479

High

139245

EMD
Emerin

1

0

High-throughput

0.458

High

1131170

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.458

High

1137344

GASP1
G-protein coupled receptor-associated sorting protein 1

1

0

High-throughput

0.458

High

1140109

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1161380

WASC2
WASH complex subunit 2

1

0

High-throughput

0.458

High

1194405

LYRIC
Protein LYRIC

1

0

High-throughput

0.458

High

1206938

Q8BNP7
Adenomatous polyposis coli N-terminal dimerisation domain-containing protein

1

0

High-throughput

0.458

High

1246953

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.458

High

69853

B1AWE1
Clathrin light chain

1

4

High-throughput

0.437

High

1102424

PSD3
PH and SEC7 domain-containing protein 3

1

2

High-throughput

0.437

High

1131322

ZDBF2
DBF4-type zinc finger-containing protein 2 homolog

1

2

High-throughput

0.437

High

1186722

AMPH
Amphiphysin

1

7

High-throughput

0.437

High

1194595

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

1

2

High-throughput

0.437

High

1206877

NYAP2
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

1

3

High-throughput

0.437

High

1206901

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

1

High-throughput

0.437

High

1321911

CISY
Citrate synthase, mitochondrial

1

2

High-throughput

0.437

High

1322232

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

3

High-throughput

0.437

High

1337474

SV2A
Synaptic vesicle glycoprotein 2A

1

3

High-throughput

0.437

High

881594

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.249

Low

1002010

KNDC1
Kinase non-catalytic C-lobe domain-containing protein 1

1

0

High-throughput

0.249

Low

1321919

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024