Protein: SMCA4
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)

Gene: SMCA4, Smarca4
Organism: Mus musculus
Interactions: 109
UniProt ID: Q3TKT4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000902 - cell morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1111926

REQU
Zinc finger protein ubi-d4

2

20

Small-scale

0.767

High

101533

F8VQD1
Polybromo 1

2

20

Small-scale

0.754

High

292068

BRD7
Bromodomain-containing protein 7

2

20

Small-scale

0.754

High

1111921

BRD9
Bromodomain-containing protein 9

2

20

Small-scale

0.754

High

1111968

PHF10
PHD finger protein 10

2

20

Small-scale

0.754

High

1111976

ACL6A
Actin-like protein 6A

2

20

Small-scale

0.737

High

956808

SMRC1
SWI/SNF complex subunit SMARCC1

7

20

Small-scale

0.735

High

57767

ARI1A
AT-rich interactive domain-containing protein 1A

6

20

Small-scale

0.721

High

222673

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

6

20

Small-scale

0.719

High

93508

ARI1B
AT-rich interactive domain-containing protein 1B

5

20

Small-scale

0.702

High

1111974

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

5

11

Small-scale

0.702

High

1111947

NSD2
Histone-lysine N-methyltransferase NSD2

1

20

Small-scale

0.691

High

590316

PO5F1
POU domain, class 5, transcription factor 1

3

15

High-throughput

0.667

High

1111935

TIF1B
Transcription intermediary factor 1-beta

1

18

Small-scale

0.646

High

1111945

PB1
Protein polybromo-1

1

18

Small-scale

0.646

High

1111940

SMRC2
SWI/SNF complex subunit SMARCC2

3

20

Small-scale

0.633

High

1111975

MECP2
Methyl-CpG-binding protein 2

3

20

Small-scale

0.633

High

929785

ACTG
Actin, cytoplasmic 2

1

17

Small-scale

0.618

High

1111917

SMCA4
Transcription activator BRG1

1

17

Small-scale

0.618

High

1111932

DDX5
Probable ATP-dependent RNA helicase DDX5

1

12

Small-scale

0.618

High

1111937

SMCA2
Probable global transcription activator SNF2L2

1

18

Small-scale

0.618

High

1111956

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

14

Small-scale

0.618

High

1111963

ACL6B
Actin-like protein 6B

1

20

Small-scale

0.618

High

1111939

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

2

20

Small-scale

0.611

High

1111927

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

20

Small-scale

0.594

High

1111934

SSXT
Protein SSXT

2

18

Small-scale

0.584

High

57185

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

17

High-throughput

0.575

High

470232

H2AZ
Histone H2A.Z

1

20

Small-scale

0.575

High

1111953

ANM5
Protein arginine N-methyltransferase 5

2

4

Small-scale

0.571

High

542772

ETS2
Protein C-ets-2

1

20

Small-scale

0.561

High

1111952

Q8C5P6
C2H2-type domain-containing protein

1

12

Small-scale

0.561

High

527151

RB
Retinoblastoma-associated protein

1

5

Small-scale

0.552

High

1111920

TF2L1
Transcription factor CP2-like protein 1

1

3

High-throughput

0.536

High

1111929

ERR2
Steroid hormone receptor ERR2

1

20

High-throughput

0.536

High

1111930

FXR1
RNA-binding protein FXR1

1

14

High-throughput

0.536

High

1111950

SALL4
Sal-like protein 4

1

10

High-throughput

0.536

High

250763

TERT
Telomerase reverse transcriptase

1

2

Small-scale

0.515

High

818702

SOX2
Transcription factor SOX-2

1

20

Small-scale

0.501

High

1111973

SRBP1
Sterol regulatory element-binding protein 1

1

18

Small-scale

0.501

High

503189

PARP1
Poly [ADP-ribose] polymerase 1

1

20

Small-scale

0.500

High

678827

SUH
Recombining binding protein suppressor of hairless

1

11

Small-scale

0.500

High

936385

HDAC2
Histone deacetylase 2

1

20

Small-scale

0.500

High

964603

TOP2A
DNA topoisomerase 2-alpha

1

11

Small-scale

0.500

High

966322

NOTC1
Neurogenic locus notch homolog protein 1

1

6

Small-scale

0.500

High

1111964

HDAC9
Histone deacetylase 9

1

3

Small-scale

0.500

High

101492

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

12

Small-scale

0.479

High

140261

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

251035

KDM6A
Lysine-specific demethylase 6A

1

10

Small-scale

0.479

High

292413

HDAC3
Histone deacetylase 3

1

20

Small-scale

0.479

High

348422

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

356850

P53
Cellular tumor antigen p53

1

9

Small-scale

0.479

High

444961

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

9

Small-scale

0.479

High

524521

MYOG
Myogenin

1

14

Small-scale

0.479

High

550203

TFE2
Transcription factor E2-alpha

1

4

High-throughput

0.479

High

570292

GATA1
Erythroid transcription factor

1

20

Small-scale

0.479

High

788271

NKX25
Homeobox protein Nkx-2.5

1

20

Small-scale

0.479

High

793808

CDX2
Homeobox protein CDX-2

1

9

Small-scale

0.479

High

837776

NKX21
Homeobox protein Nkx-2.1

1

20

Small-scale

0.479

High

862925

CEBPG
CCAAT/enhancer-binding protein gamma

1

20

Small-scale

0.479

High

868941

ATX1
Ataxin-1

1

4

High-throughput

0.479

High

886481

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

4

Small-scale

0.479

High

936507

TBX5
T-box transcription factor TBX5

1

14

Small-scale

0.479

High

945405

C2TA
MHC class II transactivator

1

3

Small-scale

0.479

High

956882

EYA1
Eyes absent homolog 1

1

9

Small-scale

0.479

High

970127

CTNB1
Catenin beta-1

1

20

Small-scale

0.479

High

980213

NF1
Neurofibromin

1

6

Small-scale

0.479

High

994722

GATA4
Transcription factor GATA-4

1

20

Small-scale

0.479

High

1111918

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.479

High

1111919

Q3UM65
Runt-related transcription factor

1

1

Small-scale

0.479

High

1111922

KDM6B
Lysine-specific demethylase 6B

1

9

Small-scale

0.479

High

1111923

NR1H4
Bile acid receptor

1

20

Small-scale

0.479

High

1111924

KLF4
Krueppel-like factor 4

1

20

High-throughput

0.479

High

1111928

E2F1
Transcription factor E2F1

1

8

Small-scale

0.479

High

1111931

GLI3
Transcriptional activator GLI3

1

5

Small-scale

0.479

High

1111933

SIX1
Homeobox protein SIX1

1

9

Small-scale

0.479

High

1111936

MYSM1
Deubiquitinase MYSM1

1

20

Small-scale

0.479

High

1111938

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

7

Small-scale

0.479

High

1111941

MBB1A
Myb-binding protein 1A

1

4

Small-scale

0.479

High

1111942

FACD2
Fanconi anemia group D2 protein homolog

1

5

High-throughput

0.479

High

1111943

NANOG
Homeobox protein NANOG

1

20

Small-scale

0.479

High

1111944

Q8BPK8
Agenet-like domain-containing protein

1

14

High-throughput

0.479

High

1111946

SRRM2
Serine/arginine repetitive matrix protein 2

1

18

Small-scale

0.479

High

1111948

CREST
Calcium-responsive transactivator

1

20

Small-scale

0.479

High

1111949

KDM4A
Lysine-specific demethylase 4A

1

13

Small-scale

0.479

High

1111951

KS6A5
Ribosomal protein S6 kinase alpha-5

1

4

Small-scale

0.479

High

1111955

KDM4C
Lysine-specific demethylase 4C

1

14

Small-scale

0.479

High

1111957

SFPQ
Splicing factor, proline- and glutamine-rich

1

16

Small-scale

0.479

High

1111958

KDM4B
Lysine-specific demethylase 4B

1

14

Small-scale

0.479

High

1111959

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

1111960

FOXP3
Forkhead box protein P3

1

20

High-throughput

0.479

High

1111961

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

17

Small-scale

0.479

High

1111962

NONO
Non-POU domain-containing octamer-binding protein

1

20

Small-scale

0.479

High

1111965

RN138
E3 ubiquitin-protein ligase RNF138

1

9

Small-scale

0.479

High

1111966

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

7

Small-scale

0.479

High

1111967

SSBP3
Single-stranded DNA-binding protein 3

1

7

Small-scale

0.479

High

1111969

Q9D982
AT rich interactive domain 2

1

20

Small-scale

0.479

High

1111970

OLIG2
Oligodendrocyte transcription factor 2

1

13

Small-scale

0.479

High

1111971

TBX21
T-box transcription factor TBX21

1

14

Small-scale

0.479

High

1111972

CAF1A
Chromatin assembly factor 1 subunit A

1

17

High-throughput

0.479

High

485945

MYOD1
Myoblast determination protein 1

1

4

Small-scale

0.445

High

661500

TBP
TATA-box-binding protein

1

3

Small-scale

0.445

High

725295

FOXA2
Hepatocyte nuclear factor 3-beta

1

20

Small-scale

0.445

High

729461

FMR1
Fragile X messenger ribonucleoprotein 1

1

14

High-throughput

0.445

High

971987

PAX5
Paired box protein Pax-5

1

14

Small-scale

0.445

High

371849

CFAD
Complement factor D

1

5

High-throughput

0.437

High

558858

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.437

High

1111925

TRAF3
TNF receptor-associated factor 3

1

3

Small-scale

0.437

High

1111954

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.437

High


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Last updated: 15 Jul 2024