Protein: AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)]

Gene: AIMP1
Organism: Homo sapiens
Interactions: 157
UniProt ID: Q12904

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0001525 - angiogenesis
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0005125 - cytokine activity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1019393

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

7

1

Small-scale

0.750

High

867690

SYRC
Arginine--tRNA ligase, cytoplasmic

6

3

Small-scale

0.732

High

1019438

OPTN
Optineurin

4

1

High-throughput

0.698

High

529044

CFTR
Cystic fibrosis transmembrane conductance regulator

3

1

High-throughput

0.662

High

1019401

SYK
Lysine--tRNA ligase

3

7

Small-scale

0.662

High

132837

SDCB1
Syntenin-1

3

0

High-throughput

0.638

High

58229

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

2

4

High-throughput

0.628

High

201588

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

2

3

High-throughput

0.628

High

430938

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

10

High-throughput

0.628

High

541352

SYDC
Aspartate--tRNA ligase, cytoplasmic

2

6

High-throughput

0.628

High

783023

SYIC
Isoleucine--tRNA ligase, cytoplasmic

2

7

High-throughput

0.628

High

814429

SYQ
Glutamine--tRNA ligase

2

7

High-throughput

0.628

High

880096

SYMC
Methionine--tRNA ligase, cytoplasmic

2

11

High-throughput

0.628

High

1019454

SYLC
Leucine--tRNA ligase, cytoplasmic

2

8

High-throughput

0.628

High

1019422

HOME1
Homer protein homolog 1

2

2

High-throughput

0.606

High

1019421

CMTD1
Catechol O-methyltransferase domain-containing protein 1

2

0

High-throughput

0.585

High

1019434

CSN5
COP9 signalosome complex subunit 5

2

0

High-throughput

0.585

High

227303

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

475681

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

2

Small-scale

0.584

High

749433

BRCA1
Breast cancer type 1 susceptibility protein

2

1

High-throughput

0.584

High

374135

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

High-throughput

0.571

High

522944

SRC
Proto-oncogene tyrosine-protein kinase Src

2

1

High-throughput

0.571

High

800764

MK08
Mitogen-activated protein kinase 8

1

1

Small-scale

0.569

High

1019448

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

2

Small-scale

0.561

High

1019439

DDRGK
DDRGK domain-containing protein 1

2

0

Small-scale

0.559

High

1019442

TSNAX
Translin-associated protein X

1

0

High-throughput

0.549

High

205339

TGON2
Trans-Golgi network integral membrane protein 2

2

0

High-throughput

0.547

High

1019406

CP135
Centrosomal protein of 135 kDa

2

0

High-throughput

0.547

High

202880

EMC8
ER membrane protein complex subunit 8

1

1

High-throughput

0.536

High

296717

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.536

High

365188

FRIH
Ferritin heavy chain

1

1

High-throughput

0.536

High

452754

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

643744

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

4

High-throughput

0.536

High

1019461

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.536

High

328827

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.515

High

429882

CATL1
Procathepsin L

1

2

High-throughput

0.515

High

538214

ENPL
Endoplasmin

1

3

Small-scale

0.515

High

648742

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.515

High

255136

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

440489

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

830943

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.513

High

1019396

CUL1
Cullin-1

1

0

High-throughput

0.513

High

1019398

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

1019399

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

1019423

GCC2
GRIP and coiled-coil domain-containing protein 2

1

0

High-throughput

0.513

High

1019426

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.513

High

1019427

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.513

High

1019430

STYX
Serine/threonine/tyrosine-interacting protein

1

0

Small-scale

0.513

High

1019441

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

0

High-throughput

0.513

High

1019467

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

1019468

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

794536

ETV4
ETS translocation variant 4

1

1

High-throughput

0.500

High

944609

ELF3
ETS-related transcription factor Elf-3

1

1

High-throughput

0.500

High

1019466

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.489

High

394626

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

902557

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

125418

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

160537

AURKA
Aurora kinase A

1

2

High-throughput

0.479

High

282638

RNF8
E3 ubiquitin-protein ligase RNF8

1

2

High-throughput

0.479

High

346652

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

377285

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

379342

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

384739

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

397940

ISG15
Ubiquitin-like protein ISG15

1

2

High-throughput

0.479

High

525922

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.479

High

569660

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

572627

VGFR1
Vascular endothelial growth factor receptor 1

1

2

High-throughput

0.479

High

609268

FGFR3
Fibroblast growth factor receptor 3

1

4

High-throughput

0.479

High

674410

UFO
Tyrosine-protein kinase receptor UFO

1

2

High-throughput

0.479

High

684671

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

707614

H2B1B
Histone H2B type 1-B

1

1

High-throughput

0.479

High

738199

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

2

High-throughput

0.479

High

835706

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.479

High

903177

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.479

High

908455

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

912876

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

917185

H4
Histone H4

1

1

High-throughput

0.479

High

918327

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

959381

VIGLN
Vigilin

1

1

High-throughput

0.479

High

965652

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.479

High

969654

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

981866

RON
Macrophage-stimulating protein receptor

1

2

High-throughput

0.479

High

1019392

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

4

High-throughput

0.479

High

1019394

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

1019395

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1019397

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

2

High-throughput

0.479

High

1019400

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1019414

SND1
Staphylococcal nuclease domain-containing protein 1

1

1

High-throughput

0.479

High

1019417

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1019432

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

1019435

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

1019444

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1019450

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.479

High

1019452

ANLN
Anillin

1

1

High-throughput

0.479

High

1019455

TRM7
tRNA

1

1

High-throughput

0.479

High

1019456

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1019460

CLC4E
C-type lectin domain family 4 member E

1

3

High-throughput

0.479

High

156277

PSA7
Proteasome subunit alpha type-7

1

0

Small-scale

0.458

High

169446

BET1
BET1 homolog

1

0

High-throughput

0.458

High

182724

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

214238

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

255731

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

272547

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

294770

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

354430

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

503988

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

617528

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

718805

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

807701

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

813420

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

817988

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

825821

NASP
Nuclear autoantigenic sperm protein

1

0

High-throughput

0.458

High

870782

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

896425

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

998622

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1019402

FSCN1
Fascin

1

0

High-throughput

0.458

High

1019403

AMOT
Angiomotin

1

0

High-throughput

0.458

High

1019404

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.458

High

1019407

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1019409

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1019411

RFIP1
Rab11 family-interacting protein 1

1

0

Small-scale

0.458

High

1019413

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

1019416

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1019419

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

1019424

MILK2
MICAL-like protein 2

1

0

High-throughput

0.458

High

1019425

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1019429

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1019433

REQU
Zinc finger protein ubi-d4

1

0

High-throughput

0.458

High

1019437

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1019443

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1019446

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.458

High

1019449

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

1019451

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1019453

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1019457

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

0

High-throughput

0.458

High

1019462

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.458

High

401915

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

1019405

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

1019408

PKHA7
Pleckstrin homology domain-containing family A member 7

1

5

High-throughput

0.445

High

1019463

ST38L
Serine/threonine-protein kinase 38-like

1

1

High-throughput

0.445

High

823942

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

1019412

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1019418

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.437

High

1019431

CLC4D
C-type lectin domain family 4 member D

1

3

High-throughput

0.437

High

1019447

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1019459

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

1017105

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.426

High

1019445

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

1019415

COX15
Heme A synthase COX15

1

0

High-throughput

0.279

Low

1019458

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

1019410

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1019420

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1019428

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1019436

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.249

Low

1019464

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1019465

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.249

Low

1019440

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024