Protein: SPICE
Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52) (Spindle and centriole-associated protein)

Gene: SPICE, SPICE1
Organism: Homo sapiens
Interactions: 187
UniProt ID: Q8N0Z3

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005814 - centriole
GO:0005819 - spindle
GO:0046599 - regulation of centriole replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1068805

PCM1
Pericentriolar material 1 protein

5

0

High-throughput

0.684

High

1229810

CE120
Centrosomal protein of 120 kDa

3

2

High-throughput

0.667

High

1229851

CE295
Centrosomal protein of 295 kDa

3

0

High-throughput

0.638

High

397046

PAI2
Plasminogen activator inhibitor 2

2

1

High-throughput

0.628

High

995036

GOGA2
Golgin subfamily A member 2

2

2

High-throughput

0.628

High

1135943

CE162
Centrosomal protein of 162 kDa

2

1

High-throughput

0.612

High

272634

OFD1
Centriole and centriolar satellite protein OFD1

2

2

High-throughput

0.611

High

1145828

CP135
Centrosomal protein of 135 kDa

2

1

High-throughput

0.611

High

901806

STXB1
Syntaxin-binding protein 1

2

1

High-throughput

0.606

High

207177

TGM5
Protein-glutamine gamma-glutamyltransferase 5

2

0

High-throughput

0.602

High

1229866

MS18A
Protein Mis18-alpha

2

0

High-throughput

0.602

High

835449

GSK3A
Glycogen synthase kinase-3 alpha

2

1

Small-scale

0.601

High

127319

IPO5
Importin-5

2

1

High-throughput

0.588

High

1229870

WRP73
WD repeat-containing protein WRAP73

2

0

Small-scale

0.585

High

300928

HAUS5
HAUS augmin-like complex subunit 5

2

0

High-throughput

0.585

High

1147723

HAUS3
HAUS augmin-like complex subunit 3

2

0

High-throughput

0.585

High

1229843

HAUS7
HAUS augmin-like complex subunit 7

2

0

High-throughput

0.585

High

1229847

HAUS8
HAUS augmin-like complex subunit 8

2

0

High-throughput

0.585

High

155036

NDC80
Kinetochore protein NDC80 homolog

2

1

High-throughput

0.584

High

1118985

AMOT
Angiomotin

2

2

High-throughput

0.584

High

1229853

VP33B
Vacuolar protein sorting-associated protein 33B

2

1

High-throughput

0.584

High

1229833

CEP63
Centrosomal protein of 63 kDa

2

2

High-throughput

0.571

High

301924

TRI37
E3 ubiquitin-protein ligase TRIM37

2

0

High-throughput

0.559

High

1229861

TRI36
E3 ubiquitin-protein ligase TRIM36

2

0

High-throughput

0.559

High

1229879

PA2G4
Proliferation-associated protein 2G4

2

0

High-throughput

0.547

High

416657

S10A6
Protein S100-A6

1

1

High-throughput

0.536

High

839496

SPB8
Serpin B8

1

1

High-throughput

0.536

High

1139398

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.536

High

1229823

TRI52
E3 ubiquitin-protein ligase TRIM52

1

1

High-throughput

0.536

High

835877

GSK3B
Glycogen synthase kinase-3 beta

1

1

Small-scale

0.515

High

183331

MEFV
Pyrin

1

0

High-throughput

0.513

High

319005

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

396261

ARGI1
Arginase-1

1

0

High-throughput

0.513

High

528382

MYH6
Myosin-6

1

0

High-throughput

0.513

High

830419

KC1E
Casein kinase I isoform epsilon

1

0

High-throughput

0.513

High

931271

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.513

High

1045976

PKP1
Plakophilin-1

1

0

High-throughput

0.513

High

1229840

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.513

High

1229856

ARP5
Actin-related protein 5

1

0

High-throughput

0.513

High

1229871

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.513

High

1229880

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.513

High

661347

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

1044498

RAB32
Ras-related protein Rab-32

1

1

High-throughput

0.489

High

116867

KIF2A
Kinesin-like protein KIF2A

1

1

High-throughput

0.479

High

259602

HMMR
Hyaluronan mediated motility receptor

1

1

High-throughput

0.479

High

317297

PCNT
Pericentrin

1

2

High-throughput

0.479

High

325803

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.479

High

408867

K1C18
Keratin, type I cytoskeletal 18

1

1

High-throughput

0.479

High

509055

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.479

High

876843

NP1L1
Nucleosome assembly protein 1-like 1

1

1

High-throughput

0.479

High

1051359

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.479

High

1066381

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1080721

ZYX
Zyxin

1

1

High-throughput

0.479

High

1108853

MA7D1
MAP7 domain-containing protein 1

1

3

High-throughput

0.479

High

1133790

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

1

High-throughput

0.479

High

1137824

CE350
Centrosome-associated protein 350

1

4

High-throughput

0.479

High

1147619

FTM
Protein fantom

1

1

High-throughput

0.479

High

1159053

CEP85
Centrosomal protein of 85 kDa

1

2

High-throughput

0.479

High

1168574

SYNE3
Nesprin-3

1

1

High-throughput

0.479

High

1172672

CE128
Centrosomal protein of 128 kDa

1

1

High-throughput

0.479

High

1200972

LUZP1
Leucine zipper protein 1

1

1

High-throughput

0.479

High

1218551

MA7D3
MAP7 domain-containing protein 3

1

3

High-throughput

0.479

High

1222725

CKP2L
Cytoskeleton-associated protein 2-like

1

1

High-throughput

0.479

High

1229816

IPO4
Importin-4

1

2

High-throughput

0.479

High

1229819

CKAP2
Cytoskeleton-associated protein 2

1

1

High-throughput

0.479

High

1229836

SPAG5
Sperm-associated antigen 5

1

1

High-throughput

0.479

High

1229842

NP1L4
Nucleosome assembly protein 1-like 4

1

1

High-throughput

0.479

High

1229848

TCHP
Trichoplein keratin filament-binding protein

1

1

High-throughput

0.479

High

1229850

CP250
Centrosome-associated protein CEP250

1

1

High-throughput

0.479

High

1229859

CENPJ
Centromere protein J

1

1

High-throughput

0.479

High

1229862

LATS2
Serine/threonine-protein kinase LATS2

1

1

High-throughput

0.479

High

1229868

CEP72
Centrosomal protein of 72 kDa

1

1

High-throughput

0.479

High

1229875

MTUS1
Microtubule-associated tumor suppressor 1

1

4

High-throughput

0.479

High

1229877

CP131
Centrosomal protein of 131 kDa

1

1

High-throughput

0.479

High

58509

CCD66
Coiled-coil domain-containing protein 66

1

0

High-throughput

0.458

High

129025

PLK4
Serine/threonine-protein kinase PLK4

1

0

High-throughput

0.458

High

162976

XPO1
Exportin-1

1

0

High-throughput

0.458

High

268493

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.458

High

387083

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

396960

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

409158

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

497286

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.458

High

538578

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.458

High

591014

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

782931

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.458

High

885804

MTPN
Myotrophin

1

0

High-throughput

0.458

High

904842

1433G
14-3-3 protein gamma

1

0

High-throughput

0.458

High

1017057

TROAP
Tastin

1

0

High-throughput

0.458

High

1093021

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

High-throughput

0.458

High

1100883

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1101508

KIF7
Kinesin-like protein KIF7

1

0

High-throughput

0.458

High

1107898

F161A
Protein FAM161A

1

0

High-throughput

0.458

High

1115636

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

1115840

MAP9
Microtubule-associated protein 9

1

0

High-throughput

0.458

High

1115888

C2CD3
C2 domain-containing protein 3

1

0

High-throughput

0.458

High

1120251

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.458

High

1146228

MAP1S
Microtubule-associated protein 1S

1

0

High-throughput

0.458

High

1158623

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

0

High-throughput

0.458

High

1172555

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.458

High

1190170

CLAP1
CLIP-associating protein 1

1

0

High-throughput

0.458

High

1190370

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.458

High

1216978

LRC49
Leucine-rich repeat-containing protein 49

1

0

High-throughput

0.458

High

1220359

SKA3
Spindle and kinetochore-associated protein 3

1

0

High-throughput

0.458

High

1229809

TEX9
Testis-expressed protein 9

1

0

High-throughput

0.458

High

1229812

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.458

High

1229814

NEDD1
Protein NEDD1

1

0

High-throughput

0.458

High

1229817

SKA2
Spindle and kinetochore-associated protein 2

1

0

High-throughput

0.458

High

1229821

PIBF1
Progesterone-induced-blocking factor 1

1

0

High-throughput

0.458

High

1229822

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1229825

SKA1
Spindle and kinetochore-associated protein 1

1

0

High-throughput

0.458

High

1229826

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.458

High

1229827

TBC31
TBC1 domain family member 31

1

0

High-throughput

0.458

High

1229830

CEP95
Centrosomal protein of 95 kDa

1

0

High-throughput

0.458

High

1229841

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.458

High

1229845

CCD77
Coiled-coil domain-containing protein 77

1

0

High-throughput

0.458

High

1229852

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1229854

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.458

High

1229858

EMAL4
Echinoderm microtubule-associated protein-like 4

1

0

High-throughput

0.458

High

1229863

DIAP3
Protein diaphanous homolog 3

1

0

High-throughput

0.458

High

1229865

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.458

High

1229874

MCTS1
Malignant T-cell-amplified sequence 1

1

0

High-throughput

0.458

High

1229876

CC14A
Dual specificity protein phosphatase CDC14A

1

0

High-throughput

0.458

High

1229878

MARE3
Microtubule-associated protein RP/EB family member 3

1

0

High-throughput

0.458

High

1229883

SKAP
Small kinetochore-associated protein

1

0

High-throughput

0.458

High

178214

IPO8
Importin-8

1

1

High-throughput

0.437

High

312323

IPO7
Importin-7

1

2

High-throughput

0.437

High

973362

TOP2B
DNA topoisomerase 2-beta

1

1

High-throughput

0.437

High

997189

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

1

High-throughput

0.437

High

1052099

MAP7
Ensconsin

1

5

High-throughput

0.437

High

1229811

F184A
Protein FAM184A

1

2

High-throughput

0.437

High

1229837

MA7D2
MAP7 domain-containing protein 2

1

3

High-throughput

0.437

High

1229864

TXLNG
Gamma-taxilin

1

1

High-throughput

0.437

High

232316

KDM1A
Lysine-specific histone demethylase 1A

4

0

High-throughput

0.360

High

1159680

PLBL1
Phospholipase B-like 1

2

0

High-throughput

0.328

High

1229860

MED4
Mediator of RNA polymerase II transcription subunit 4

2

0

High-throughput

0.305

High

1229828

PTCD3
Small ribosomal subunit protein mS39

2

0

High-throughput

0.298

High

438806

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.279

Low

786621

STA5A
Signal transducer and activator of transcription 5A

1

0

High-throughput

0.279

Low

1229818

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

1229824

RGMA
Repulsive guidance molecule A

1

0

High-throughput

0.279

Low

1229835

PHF12
PHD finger protein 12

1

0

High-throughput

0.279

Low

1229844

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

1229873

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

118885

GTPB1
GTP-binding protein 1

1

0

High-throughput

0.249

Low

166584

DCLK1
Serine/threonine-protein kinase DCLK1

1

0

High-throughput

0.249

Low

182824

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

262031

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.249

Low

266569

GPC4
Glypican-4

1

0

High-throughput

0.249

Low

283563

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.249

Low

315389

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.249

Low

417741

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

444422

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.249

Low

519227

KCRB
Creatine kinase B-type

1

0

High-throughput

0.249

Low

553159

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

651661

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

745224

RBMX
RNA-binding motif protein, X chromosome

1

0

High-throughput

0.249

Low

777892

RFC5
Replication factor C subunit 5

1

0

High-throughput

0.249

Low

823443

PAXI
Paxillin

1

0

High-throughput

0.249

Low

878340

NH2L1
NHP2-like protein 1

1

0

High-throughput

0.249

Low

895167

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.249

Low

925072

TRA2B
Transformer-2 protein homolog beta

1

0

High-throughput

0.249

Low

996763

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.249

Low

1022540

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.249

Low

1070291

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.249

Low

1125514

PDZ11
PDZ domain-containing protein 11

1

0

High-throughput

0.249

Low

1133684

RHG21
Rho GTPase-activating protein 21

1

0

High-throughput

0.249

Low

1146605

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.249

Low

1229813

ARI1B
AT-rich interactive domain-containing protein 1B

1

0

High-throughput

0.249

Low

1229815

DDX54
ATP-dependent RNA helicase DDX54

1

0

High-throughput

0.249

Low

1229820

PHIP
PH-interacting protein

1

0

High-throughput

0.249

Low

1229829

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.249

Low

1229831

ZC21A
Zinc finger C2HC domain-containing protein 1A

1

0

High-throughput

0.249

Low

1229832

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1229834

ZDH15
Palmitoyltransferase ZDHHC15

1

0

Small-scale

0.249

Low

1229838

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

0

High-throughput

0.249

Low

1229839

RBM15
RNA-binding protein 15

1

0

High-throughput

0.249

Low

1229846

NOL10
Nucleolar protein 10

1

0

High-throughput

0.249

Low

1229849

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.249

Low

1229855

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.249

Low

1229857

PKHA5
Pleckstrin homology domain-containing family A member 5

1

0

High-throughput

0.249

Low

1229867

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.249

Low

1229869

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.249

Low

1229872

RALY
RNA-binding protein Raly

1

0

High-throughput

0.249

Low

1229881

NOP58
Nucleolar protein 58

1

0

High-throughput

0.249

Low

1229882

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

High-throughput

0.249

Low

1229884

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

1132638

CHCH9
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024