Protein: PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein)

Gene: PHLP1, Phlpp1
Organism: Mus musculus
Interactions: 31
UniProt ID: Q8CHE4

Gene Ontology (top 5):
GO:0002667 - regulation of T cell anergy
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1296547

WDR48
WD repeat-containing protein 48

1

5

High-throughput

0.618

High

1298613

CSTF1
Cleavage stimulation factor subunit 1

1

1

High-throughput

0.553

High

1298617

ARHG7
Rho guanine nucleotide exchange factor 7

1

2

High-throughput

0.553

High

1298614

BRAP
BRCA1-associated protein

1

2

Small-scale

0.515

High

59754

SKT
Sickle tail protein

1

1

High-throughput

0.479

High

936156

AQP4
Aquaporin-4

1

2

High-throughput

0.479

High

1189947

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1222592

SOAT1
Sterol O-acyltransferase 1

1

1

High-throughput

0.479

High

1242763

NEST
Nestin

1

7

High-throughput

0.479

High

1296805

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

8

High-throughput

0.479

High

1298616

TSC1
Hamartin

1

3

High-throughput

0.479

High

148195

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

1022131

DAB2
Disabled homolog 2

1

0

High-throughput

0.458

High

1189537

Q3TQ10
TSC complex subunit 2

1

0

High-throughput

0.458

High

1190582

MCU
Calcium uniporter protein, mitochondrial

1

0

High-throughput

0.458

High

1221563

CNOT7
CCR4-NOT transcription complex subunit 7

1

0

High-throughput

0.458

High

1295965

U2AF4
Splicing factor U2AF 26 kDa subunit

1

0

High-throughput

0.458

High

1298611

CAHM5
Calcium homeostasis modulator protein 5

1

0

High-throughput

0.458

High

1298612

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.458

High

1298615

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

60020

ARI1A
AT-rich interactive domain-containing protein 1A

1

1

High-throughput

0.437

High

98331

E9QLJ0
Cardiomyopathy-associated protein 5

1

8

High-throughput

0.437

High

1190397

Q3UKG2
Proline rich basic protein 1

1

3

High-throughput

0.437

High

1298610

SMTL2
Smoothelin-like protein 2

1

8

High-throughput

0.437

High

98181

E9Q6E5
Serine and arginine-rich splicing factor 11

1

0

High-throughput

0.249

Low

313030

RPP30
Ribonuclease P protein subunit p30

1

0

High-throughput

0.249

Low

715013

FETUA
Alpha-2-HS-glycoprotein

1

0

High-throughput

0.249

Low

1054093

ATP5I
ATP synthase F(0) complex subunit e, mitochondrial

1

0

High-throughput

0.249

Low

1190789

FCHO2
F-BAR domain only protein 2

1

0

High-throughput

0.249

Low

1298618

Q9JL91
Nebulin

1

0

High-throughput

0.249

Low

1298619

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025