Protein: DLDH
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase)

Gene: DLDH, Dld
Organism: Mus musculus
Interactions: 69
UniProt ID: O08749

Gene Ontology (top 5):
GO:0004148 - dihydrolipoyl dehydrogenase (NADH) activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005929 - cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

148151

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

3

16

High-throughput

0.827

High

148193

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

2

16

High-throughput

0.754

High

148194

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

16

High-throughput

0.618

High

148184

HDAC4
Histone deacetylase 4

1

1

High-throughput

0.536

High

108337

G3X9H5
Huntingtin

2

1

High-throughput

0.533

High

148171

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

0

High-throughput

0.513

High

147671

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

High-throughput

0.479

High

148153

CFAD
Complement factor D

1

1

High-throughput

0.479

High

148154

MDHM
Malate dehydrogenase, mitochondrial

1

6

High-throughput

0.479

High

148157

ODPAT
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

1

7

High-throughput

0.479

High

148160

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

1

High-throughput

0.479

High

148161

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

3

High-throughput

0.479

High

148165

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

High-throughput

0.479

High

148172

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.479

High

148174

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

1

High-throughput

0.479

High

148178

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

9

High-throughput

0.479

High

148190

WDR48
WD repeat-containing protein 48

1

3

High-throughput

0.479

High

148192

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

1

High-throughput

0.479

High

148206

GAL3A
Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial

1

1

High-throughput

0.479

High

148207

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

15

High-throughput

0.479

High

148209

ETFB
Electron transfer flavoprotein subunit beta

1

3

High-throughput

0.479

High

148212

FOXO3
Forkhead box protein O3

1

1

High-throughput

0.479

High

148156

SSR3
Somatostatin receptor type 3

1

0

High-throughput

0.458

High

148162

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

148170

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.458

High

148173

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.458

High

148188

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.458

High

148195

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

148202

HSPB2
Heat shock protein beta-2

1

0

High-throughput

0.458

High

148203

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.458

High

148210

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.458

High

148152

IKBE
NF-kappa-B inhibitor epsilon

1

1

High-throughput

0.457

High

148158

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.445

High

148159

CAV3
Caveolin-3

1

2

High-throughput

0.445

High

148163

ACTN4
Alpha-actinin-4

1

3

High-throughput

0.445

High

148164

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

11

High-throughput

0.445

High

148166

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.445

High

148167

1433Z
14-3-3 protein zeta/delta

1

11

High-throughput

0.445

High

148168

1433T
14-3-3 protein theta

1

11

High-throughput

0.445

High

148176

TR150
Thyroid hormone receptor-associated protein 3

1

3

High-throughput

0.445

High

148179

PRDX2
Peroxiredoxin-2

1

10

High-throughput

0.445

High

148181

HS105
Heat shock protein 105 kDa

1

8

High-throughput

0.445

High

148196

BCLF1
Bcl-2-associated transcription factor 1

1

3

High-throughput

0.445

High

148199

PRP19
Pre-mRNA-processing factor 19

1

2

High-throughput

0.445

High

148200

PARK7
Parkinson disease protein 7 homolog

1

1

High-throughput

0.445

High

148204

1433B
14-3-3 protein beta/alpha

1

11

High-throughput

0.445

High

148205

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

4

High-throughput

0.445

High

148211

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

1

High-throughput

0.445

High

148213

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.445

High

148186

NEB2
Neurabin-2

1

1

High-throughput

0.437

High

148189

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

1

High-throughput

0.437

High

148197

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.437

High

148198

PODO
Podocin

1

3

Small-scale

0.437

High

148183

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.426

High

148191

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

0

High-throughput

0.426

High

148201

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.426

High

59431

A2AKD7
Alpha-1-syntrophin

1

1

High-throughput

0.407

High

97933

RYR2
Ryanodine receptor 2

1

2

High-throughput

0.407

High

98038

DESP
Desmoplakin

1

1

High-throughput

0.407

High

148155

ENOB
Beta-enolase

1

4

High-throughput

0.407

High

148180

HSP74
Heat shock 70 kDa protein 4

1

7

High-throughput

0.407

High

148185

ABCF1
ATP-binding cassette sub-family F member 1

1

1

High-throughput

0.407

High

148187

ACTN1
Alpha-actinin-1

1

3

High-throughput

0.407

High

148208

AP3S1
AP-3 complex subunit sigma-1

1

3

High-throughput

0.407

High

148177

CLU
Clustered mitochondria protein homolog

1

0

High-throughput

0.249

Low

148169

KCNQ1
Potassium voltage-gated channel subfamily KQT member 1

1

0

High-throughput

0.232

Low

148175

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.232

Low

148182

DLG4
Disks large homolog 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025