Protein: FCN1
Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin)

Gene: FCN1
Organism: Homo sapiens
Interactions: 72
UniProt ID: O00602

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0001867 - complement activation, lectin pathway
GO:0002752 - cell surface pattern recognition receptor signaling pathway
GO:0003823 - antigen binding
GO:0005102 - signaling receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

134535

FCN2
Ficolin-2

3

15

High-throughput

0.861

High

60247

POTEF
POTE ankyrin domain family member F

3

2

High-throughput

0.667

High

134502

DJC13
DnaJ homolog subfamily C member 13

3

1

High-throughput

0.667

High

134518

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

3

4

High-throughput

0.667

High

134520

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

3

4

High-throughput

0.667

High

134542

SE6L2
Seizure 6-like protein 2

3

14

High-throughput

0.667

High

134557

K1549
UPF0606 protein KIAA1549

3

4

High-throughput

0.667

High

134506

PIGR
Polymeric immunoglobulin receptor

1

0

High-throughput

0.656

High

134423

PODXL
Podocalyxin

3

0

High-throughput

0.638

High

134546

K319L
Dyslexia-associated protein KIAA0319-like protein

3

0

High-throughput

0.638

High

134497

FCN1
Ficolin-1

1

15

Small-scale

0.590

High

134509

CRP

1

5

Small-scale

0.536

High

134511

TRFL
Lactotransferrin

1

2

High-throughput

0.536

High

134515

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.536

High

134525

LCN1
Lipocalin-1

1

1

High-throughput

0.536

High

134530

NGAL
Neutrophil gelatinase-associated lipocalin

1

1

High-throughput

0.536

High

134533

LG3BP
Galectin-3-binding protein

1

2

High-throughput

0.536

High

119677

MASP2
Mannan-binding lectin serine protease 2

1

11

Small-scale

0.515

High

134527

MASP1
Mannan-binding lectin serine protease 1

1

13

Small-scale

0.515

High

134505

IGJ
Immunoglobulin J chain

1

0

High-throughput

0.513

High

134548

BPIB1
BPI fold-containing family B member 1

1

0

High-throughput

0.513

High

134550

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.513

High

120110

TLR4
Toll-like receptor 4

1

4

Small-scale

0.501

High

134510

FINC
Fibronectin

1

9

Small-scale

0.501

High

134514

UROM
Uromodulin

1

11

Small-scale

0.501

High

134516

ELN
Elastin

1

2

Small-scale

0.501

High

129866

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

2

High-throughput

0.489

High

134540

KLH22
Kelch-like protein 22

1

1

High-throughput

0.489

High

134554

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

1

High-throughput

0.489

High

134519

FBLN1
Fibulin-1

1

7

High-throughput

0.479

High

134523

PTX3
Pentraxin-related protein PTX3

1

5

Small-scale

0.479

High

134498

MA2B1
Lysosomal alpha-mannosidase

1

2

Small-scale

0.457

High

134500

FFAR2
Free fatty acid receptor 2

1

4

Small-scale

0.457

High

134508

IGHA1
Immunoglobulin heavy constant alpha 1

1

5

Small-scale

0.457

High

134517

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

Small-scale

0.457

High

134524

GRAN
Grancalcin

1

2

Small-scale

0.457

High

134532

TNFC
Lymphotoxin-beta

1

1

Small-scale

0.457

High

134534

MBTP1
Membrane-bound transcription factor site-1 protease

1

3

Small-scale

0.457

High

134536

ZYX
Zyxin

1

3

Small-scale

0.457

High

134551

PDLI5
PDZ and LIM domain protein 5

1

2

Small-scale

0.457

High

134553

EMIL2
EMILIN-2

1

1

Small-scale

0.457

High

134558

WDR6
tRNA

1

1

Small-scale

0.457

High

134559

MMP25
Matrix metalloproteinase-25

1

2

Small-scale

0.457

High

134561

STK24
Serine/threonine-protein kinase 24

1

7

Small-scale

0.457

High

134504

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

3

Small-scale

0.445

High

134507

IGKC
Immunoglobulin kappa constant

1

2

High-throughput

0.445

High

134512

MT2
Metallothionein-2

1

0

Small-scale

0.438

High

134513

S10A9
Protein S100-A9

1

0

Small-scale

0.438

High

134521

COF1
Cofilin-1

1

0

Small-scale

0.438

High

134522

FSHR
Follicle-stimulating hormone receptor

1

0

Small-scale

0.438

High

134526

ARL4A
ADP-ribosylation factor-like protein 4A

1

0

Small-scale

0.438

High

134531

IN35
Interferon-induced 35 kDa protein

1

0

Small-scale

0.438

High

134537

ZXDC
Zinc finger protein ZXDC

1

0

Small-scale

0.438

High

134541

PVRIG
Transmembrane protein PVRIG

1

0

Small-scale

0.438

High

134544

ASXL1
Polycomb group protein ASXL1

1

0

Small-scale

0.438

High

134560

HCST
Hematopoietic cell signal transducer

1

0

Small-scale

0.438

High

134545

GT252
Procollagen galactosyltransferase 2

1

2

High-throughput

0.437

High

134499

CCS
Copper chaperone for superoxide dismutase

1

1

Small-scale

0.417

High

134549

SARAF
Store-operated calcium entry-associated regulatory factor

1

3

Small-scale

0.417

High

134501

SUSD5
Sushi domain-containing protein 5

3

0

High-throughput

0.347

High

134556

TRABD
TraB domain-containing protein

2

0

High-throughput

0.328

High

134503

ZMYM6
Zinc finger MYM-type protein 6

1

0

High-throughput

0.279

Low

134543

NUD18
8-oxo-dGDP phosphatase NUDT18

1

0

High-throughput

0.279

Low

134547

CH058
Uncharacterized protein C8orf58

1

0

High-throughput

0.269

Low

134538

TM52B
Transmembrane protein 52B

1

0

High-throughput

0.249

Low

61843

CC88B
Coiled-coil domain-containing protein 88B

1

0

Small-scale

0.238

Low

134528

GDIR2
Rho GDP-dissociation inhibitor 2

1

0

Small-scale

0.238

Low

134529

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

Small-scale

0.238

Low

134539

MIDN
Midnolin

1

0

Small-scale

0.238

Low

134552

SEN34
tRNA-splicing endonuclease subunit Sen34

1

0

Small-scale

0.238

Low

134555

I27L2
Interferon alpha-inducible protein 27-like protein 2

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024